This term is obsolete.

GO:0008713 JSON

ADP-heptose-lipopolysaccharide heptosyltransferase activity

Molecular Function

Definition (GO:0008713 GONUTS page)

Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.

66,784 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ADP-heptose:LPS heptosyltransferase activity exact

Ancestor Chart

Ancestor chart for GO:0008713
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Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016757 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A6KJI3 10116 A6KJI3_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D6WQD5 7070 D6WQD5_TRICA GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q6AYL7 10116 Q6AYL7_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7JRM5 7227 Q7JRM5_DROME GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 2.4.99.24
MetaCyc RXN-22477
RHEA 74071

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:61506 ADP-L-glycero-beta-D-manno-heptose(2-)
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:456216 ADP(3-)
has_participant CHEBI CHEBI:193069 an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A(6-)
has_participant CHEBI CHEBI:193068 an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A(6-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008713 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0008713
ADP-heptose-lipopolysaccharide heptosyltransferase activity
2,967.41 100.00 66,777 66,777
GO:0009244
lipopolysaccharide core region biosynthetic process
1,376.79 46.23 66,249 142,787
GO:0008920
lipopolysaccharide heptosyltransferase activity
2,965.71 10.46 6,984 6,988
GO:0009103
lipopolysaccharide biosynthetic process
140.00 4.27 20,628 437,238
GO:0016757
glycosyltransferase activity
60.82 2.05 65,093 3,176,052
GO:0005829
cytosol
14.16 0.48 66,746 13,989,509
GO:0009247
glycolipid biosynthetic process
5.94 0.12 209 104,459
GO:0005886
plasma membrane
0.93 0.03 7,193 22,848,296
GO:0016791
phosphatase activity
0.74 0.02 180 717,322
GO:0016740
transferase activity
0.33 0.01 780 7,114,403
Totals 303142 251273573
No co-occurrence statistics for GO:0008713 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0008713
ADP-heptose-lipopolysaccharide heptosyltransferase activity
22,055.20 100.00 64 64
GO:0009244
lipopolysaccharide core region biosynthetic process
10,693.43 48.48 64 132
GO:0071968
lipid A-core heptosyltransferase activity
22,055.20 3.13 2 2
GO:0008920
lipopolysaccharide heptosyltransferase activity
22,055.20 3.13 2 2
GO:0071967
lipopolysaccharide core heptosyltransferase activity
22,055.20 1.56 1 1
GO:0009103
lipopolysaccharide biosynthetic process
115.47 0.39 1 191
GO:0005829
cytosol
15.76 0.07 64 89,580
GO:0005515
protein binding
0.53 0.00 1 41,833
Totals 199 131805

Change Log

Timestamp Action Category Detail
2024-09-05 Added XREF RHEA:74071
2024-09-05 Added XREF EC:2.4.99.24
2024-09-05 Added XREF MetaCyc:RXN-22477
2024-09-05 Deleted XREF RHEA:28538
2024-09-05 Deleted XREF MetaCyc:RXN0-5061
2020-06-22 Added XREF RHEA:28538
2010-10-17 Added SYNONYM ADP-heptose:LPS heptosyltransferase activity
2010-10-17 Added DEFINITION Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.
2010-10-17 Added XREF MetaCyc:RXN0-5061
2008-04-01 Updated RELATION is a GO:0008920 (lipopolysaccharide heptosyltransferase activity)
Timestamp Action Category Detail
2003-03-19 Updated TERM ADP-heptose-lipopolysaccharide heptosyltransferase activity
2002-02-06 Updated TERM ADP-heptose-lipopolysaccharide heptosyltransferase
2001-11-07 Updated TERM ADP-heptose-lipopolysaccharide heptosyltransferase
2001-04-03 Updated TERM ADP-heptose--lipopolysaccharide heptosyltransferase
2001-03-30 Added TERM ADP-heptose--lipopolysaccharide heptosyltransferase
Timestamp Action Category Detail
2010-10-17 Added SYNONYM ADP-heptose:LPS heptosyltransferase activity
2010-10-17 Added DEFINITION Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008920 (lipopolysaccharide heptosyltransferase activity)
Timestamp Action Category Detail
2024-09-05 Added XREF RHEA:74071
2024-09-05 Added XREF EC:2.4.99.24
2024-09-05 Added XREF MetaCyc:RXN-22477
2024-09-05 Deleted XREF RHEA:28538
2024-09-05 Deleted XREF MetaCyc:RXN0-5061
2020-06-22 Added XREF RHEA:28538
2010-10-17 Added XREF MetaCyc:RXN0-5061
Timestamp Action Category Detail
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