GO:0008761
JSON
UDP-N-acetylglucosamine 2-epimerase activity
Molecular Function
Definition (GO:0008761 GONUTS page)
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
uridine diphosphate-N-acetylglucosamine-2'-epimerase activity | related |
UDP-GlcNAc-2-epimerase activity | related |
uridine diphospho-N-acetylglucosamine 2'-epimerase activity | related |
uridine diphosphoacetylglucosamine 2'-epimerase activity | related |
UDP-N-acetylglucosamine 2'-epimerase activity | related |
UDP-N-acetyl-D-glucosamine 2-epimerase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.1.3.14 | |
InterPro | IPR029767 | UDP-N-acetylglucosamine 2-epimerase WecB-like |
InterPro | IPR032892 | UDP-N-acetylglucosamine 2-epimerase WecB |
MetaCyc | UDPGLCNACEPIM-RXN | |
RHEA | 17213 | |
Reactome | R-HSA-4085021 | |
Reactome | R-HSA-4088338 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57705 | UDP-N-acetyl-alpha-D-glucosamine(2-) |
has_participant | CHEBI | CHEBI:68623 | UDP-N-acetyl-alpha-D-mannosamine(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008761 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
UDP-N-acetylglucosamine 2-epimerase activity
|
4,606.74 | 100.00 | 42,316 | 42,316 |
N-acylmannosamine kinase activity
|
1,963.44 | 7.16 | 3,353 | 7,867 |
UDP-N-acetylglucosamine metabolic process
|
408.82 | 5.96 | 6,489 | 73,120 |
enterobacterial common antigen biosynthetic process
|
160.74 | 1.62 | 1,237 | 35,451 |
carbohydrate phosphorylation
|
53.70 | 1.03 | 3,353 | 287,637 |
isomerase activity
|
47.15 | 1.02 | 32,579 | 3,183,067 |
catalytic activity
|
42.94 | 0.93 | 41,928 | 4,498,570 |
hydrolase activity, hydrolyzing O-glycosyl compounds
|
25.75 | 0.54 | 6,489 | 1,160,741 |
UDP-N,N'-diacetylbacillosamine 2-epimerase activity
|
4,583.71 | 0.47 | 199 | 200 |
GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity
|
4,583.71 | 0.47 | 199 | 200 |
Totals | 144090 | 230313479 |
No co-occurrence statistics for GO:0008761 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
UDP-N-acetylglucosamine 2-epimerase activity
|
47,844.41 | 100.00 | 27 | 27 |
N-acylmannosamine kinase activity
|
33,772.52 | 64.86 | 24 | 34 |
N-acetylneuraminate biosynthetic process
|
5,467.93 | 6.90 | 4 | 35 |
CMP-N-acetylneuraminate biosynthetic process
|
6,379.25 | 5.00 | 2 | 15 |
UDP-glucuronate 4-epimerase activity
|
23,922.20 | 3.57 | 1 | 2 |
N-acetylneuraminate metabolic process
|
3,987.03 | 2.63 | 1 | 12 |
enterobacterial common antigen biosynthetic process
|
1,649.81 | 1.82 | 1 | 29 |
O antigen biosynthetic process
|
1,139.15 | 1.47 | 1 | 42 |
catalytic activity
|
260.02 | 0.48 | 1 | 184 |
polysaccharide biosynthetic process
|
183.31 | 0.35 | 1 | 261 |
Totals | 77 | 196421 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | uridine diphospho-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | uridine diphosphate-N-acetylglucosamine-2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | uridine diphosphoacetylglucosamine 2'-epimerase activity |
2020-10-08 | Added | SYNONYM | UDP-N-acetyl-D-glucosamine 2-epimerase activity |
2020-10-08 | Added | SYNONYM | UDP-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Added | SYNONYM | uridine diphosphate-N-acetylglucosamine-2'-epimerase activity |
2020-10-08 | Added | SYNONYM | UDP-GlcNAc-2-epimerase activity |
2020-10-08 | Added | SYNONYM | uridine diphosphoacetylglucosamine 2'-epimerase activity |
2020-10-08 | Added | SYNONYM | uridine diphospho-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | UDP-N-acetyl-D-glucosamine 2-epimerase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | UDP-N-acetylglucosamine 2-epimerase activity |
2002-02-06 | Updated | TERM | UDP-N-acetylglucosamine 2-epimerase |
2001-04-03 | Updated | TERM | UDP-N-acetylglucosamine 2-epimerase |
2001-03-30 | Added | TERM | UDP-N-acetylglucosamine 2-epimerase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | uridine diphospho-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | uridine diphosphate-N-acetylglucosamine-2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | uridine diphosphoacetylglucosamine 2'-epimerase activity |
2020-10-08 | Added | SYNONYM | UDP-N-acetyl-D-glucosamine 2-epimerase activity |
2020-10-08 | Added | SYNONYM | UDP-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Added | SYNONYM | uridine diphosphate-N-acetylglucosamine-2'-epimerase activity |
2020-10-08 | Added | SYNONYM | UDP-GlcNAc-2-epimerase activity |
2020-10-08 | Added | SYNONYM | uridine diphosphoacetylglucosamine 2'-epimerase activity |
2020-10-08 | Added | SYNONYM | uridine diphospho-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | UDP-N-acetyl-D-glucosamine 2-epimerase activity |
2020-10-08 | Deleted | SYNONYM | UDP-N-acetylglucosamine 2'-epimerase activity |
2020-10-08 | Deleted | SYNONYM | UDP-GlcNAc-2-epimerase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine. |
2007-11-08 | Added | SYNONYM | UDP-N-acetylglucosamine 2'-epimerase activity |
2007-11-08 | Added | SYNONYM | UDP-N-acetyl-D-glucosamine 2-epimerase activity |
2007-09-06 | Added | SYNONYM | uridine diphosphate-N-acetylglucosamine-2'-epimerase activity |
2007-09-06 | Added | SYNONYM | uridine diphospho-N-acetylglucosamine 2'-epimerase activity |
2007-09-06 | Added | SYNONYM | uridine diphosphoacetylglucosamine 2'-epimerase activity |
2007-09-06 | Added | SYNONYM | UDP-GlcNAc-2-epimerase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016857 (racemase and epimerase activity, acting on carbohydrates and derivatives) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-05-04 | Added | XREF | Reactome:R-HSA-4088338 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-4088338 |
2019-04-29 | Added | XREF | Reactome:R-HSA-4088338 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-4088338 |
2019-04-27 | Added | XREF | Reactome:R-HSA-4088338 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-4088338 |
2019-04-01 | Added | XREF | Reactome:R-HSA-4085021 |
2019-04-01 | Added | XREF | Reactome:R-HSA-4088338 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-4085021 |
2018-12-11 | Added | XREF | reactome:R-HSA-4085021 |
2018-07-13 | Added | XREF | RHEA:17213 |
2018-07-13 | Deleted | XREF | RHEA:17216 |
2011-09-16 | Added | XREF | RHEA:17216 |
2003-10-27 | Added | XREF | MetaCyc:UDPGLCNACEPIM-RXN |
2001-03-30 | Added | XREF | EC:5.1.3.14 |
Timestamp | Action | Category | Detail |
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