This term is obsolete.

GO:0008761 JSON

UDP-N-acetylglucosamine 2-epimerase activity

Molecular Function

Definition (GO:0008761 GONUTS page)

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.

42,341 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
uridine diphosphate-N-acetylglucosamine-2'-epimerase activity related
UDP-GlcNAc-2-epimerase activity related
uridine diphospho-N-acetylglucosamine 2'-epimerase activity related
uridine diphosphoacetylglucosamine 2'-epimerase activity related
UDP-N-acetylglucosamine 2'-epimerase activity related
UDP-N-acetyl-D-glucosamine 2-epimerase activity related

Ancestor Chart

Ancestor chart for GO:0008761
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 5.1.3.14
InterPro IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like
InterPro IPR032892 UDP-N-acetylglucosamine 2-epimerase WecB
MetaCyc UDPGLCNACEPIM-RXN
RHEA 17213
Reactome R-HSA-4085021
Reactome R-HSA-4088338

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57705 UDP-N-acetyl-alpha-D-glucosamine(2-)
has_participant CHEBI CHEBI:68623 UDP-N-acetyl-alpha-D-mannosamine(2-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008761 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term PR S% #Together #Compared
UDP-N-acetylglucosamine 2-epimerase activity
4,606.74 100.00 42,316 42,316
N-acylmannosamine kinase activity
1,963.44 7.16 3,353 7,867
UDP-N-acetylglucosamine metabolic process
408.82 5.96 6,489 73,120
enterobacterial common antigen biosynthetic process
160.74 1.62 1,237 35,451
carbohydrate phosphorylation
53.70 1.03 3,353 287,637
isomerase activity
47.15 1.02 32,579 3,183,067
catalytic activity
42.94 0.93 41,928 4,498,570
hydrolase activity, hydrolyzing O-glycosyl compounds
25.75 0.54 6,489 1,160,741
UDP-N,N'-diacetylbacillosamine 2-epimerase activity
4,583.71 0.47 199 200
GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity
4,583.71 0.47 199 200
Totals 144090 230313479
No co-occurrence statistics for GO:0008761 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term PR S% #Together #Compared
UDP-N-acetylglucosamine 2-epimerase activity
47,844.41 100.00 27 27
N-acylmannosamine kinase activity
33,772.52 64.86 24 34
N-acetylneuraminate biosynthetic process
5,467.93 6.90 4 35
CMP-N-acetylneuraminate biosynthetic process
6,379.25 5.00 2 15
UDP-glucuronate 4-epimerase activity
23,922.20 3.57 1 2
N-acetylneuraminate metabolic process
3,987.03 2.63 1 12
enterobacterial common antigen biosynthetic process
1,649.81 1.82 1 29
O antigen biosynthetic process
1,139.15 1.47 1 42
catalytic activity
260.02 0.48 1 184
polysaccharide biosynthetic process
183.31 0.35 1 261
Totals 77 196421

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM uridine diphospho-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Deleted SYNONYM uridine diphosphate-N-acetylglucosamine-2'-epimerase activity
2020-10-08 Deleted SYNONYM uridine diphosphoacetylglucosamine 2'-epimerase activity
2020-10-08 Added SYNONYM UDP-N-acetyl-D-glucosamine 2-epimerase activity
2020-10-08 Added SYNONYM UDP-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Added SYNONYM uridine diphosphate-N-acetylglucosamine-2'-epimerase activity
2020-10-08 Added SYNONYM UDP-GlcNAc-2-epimerase activity
2020-10-08 Added SYNONYM uridine diphosphoacetylglucosamine 2'-epimerase activity
2020-10-08 Added SYNONYM uridine diphospho-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Deleted SYNONYM UDP-N-acetyl-D-glucosamine 2-epimerase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM UDP-N-acetylglucosamine 2-epimerase activity
2002-02-06 Updated TERM UDP-N-acetylglucosamine 2-epimerase
2001-04-03 Updated TERM UDP-N-acetylglucosamine 2-epimerase
2001-03-30 Added TERM UDP-N-acetylglucosamine 2-epimerase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM uridine diphospho-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Deleted SYNONYM uridine diphosphate-N-acetylglucosamine-2'-epimerase activity
2020-10-08 Deleted SYNONYM uridine diphosphoacetylglucosamine 2'-epimerase activity
2020-10-08 Added SYNONYM UDP-N-acetyl-D-glucosamine 2-epimerase activity
2020-10-08 Added SYNONYM UDP-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Added SYNONYM uridine diphosphate-N-acetylglucosamine-2'-epimerase activity
2020-10-08 Added SYNONYM UDP-GlcNAc-2-epimerase activity
2020-10-08 Added SYNONYM uridine diphosphoacetylglucosamine 2'-epimerase activity
2020-10-08 Added SYNONYM uridine diphospho-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Deleted SYNONYM UDP-N-acetyl-D-glucosamine 2-epimerase activity
2020-10-08 Deleted SYNONYM UDP-N-acetylglucosamine 2'-epimerase activity
2020-10-08 Deleted SYNONYM UDP-GlcNAc-2-epimerase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
2007-11-08 Added SYNONYM UDP-N-acetylglucosamine 2'-epimerase activity
2007-11-08 Added SYNONYM UDP-N-acetyl-D-glucosamine 2-epimerase activity
2007-09-06 Added SYNONYM uridine diphosphate-N-acetylglucosamine-2'-epimerase activity
2007-09-06 Added SYNONYM uridine diphospho-N-acetylglucosamine 2'-epimerase activity
2007-09-06 Added SYNONYM uridine diphosphoacetylglucosamine 2'-epimerase activity
2007-09-06 Added SYNONYM UDP-GlcNAc-2-epimerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016857 (racemase and epimerase activity, acting on carbohydrates and derivatives)
Timestamp Action Category Detail
2019-05-04 Added XREF Reactome:R-HSA-4088338
2019-04-30 Deleted XREF Reactome:R-HSA-4088338
2019-04-29 Added XREF Reactome:R-HSA-4088338
2019-04-28 Deleted XREF Reactome:R-HSA-4088338
2019-04-27 Added XREF Reactome:R-HSA-4088338
2019-04-23 Deleted XREF Reactome:R-HSA-4088338
2019-04-01 Added XREF Reactome:R-HSA-4085021
2019-04-01 Added XREF Reactome:R-HSA-4088338
2019-04-01 Deleted XREF reactome:R-HSA-4085021
2018-12-11 Added XREF reactome:R-HSA-4085021
2018-07-13 Added XREF RHEA:17213
2018-07-13 Deleted XREF RHEA:17216
2011-09-16 Added XREF RHEA:17216
2003-10-27 Added XREF MetaCyc:UDPGLCNACEPIM-RXN
2001-03-30 Added XREF EC:5.1.3.14
Timestamp Action Category Detail
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