This term is obsolete.

GO:0008810 JSON

cellulase activity

Molecular Function

Definition (GO:0008810 GONUTS page)

Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

45,861 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
endo-1,4-beta-glucanase activity broad
endoglucanase D related
celludextrinase activity related
cellulosin AP related
beta-1,4-glucanase activity broad
carboxymethyl cellulase activity narrow
cellulase A 3 related
1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity related
9.5 cellulase activity related
celluase A related

Ancestor Chart

Ancestor chart for GO:0008810
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A3DHD2 203119 CBDP_ACET2 GO:0008810 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25286843
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q91YD4 10090 TRPM2_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-references

Database ID Description
EC 3.2.1.4
InterPro IPR000334 Glycoside hydrolase, family 45
InterPro IPR000556 Glycoside hydrolase, 48F
InterPro IPR002594 Glycoside hydrolase family 12
InterPro IPR004197 Cellulase, Ig-like domain
InterPro IPR005086 Carbohydrate binding module family 17/28
InterPro IPR005087 Carbohydrate binding module family 11
MetaCyc RXN-2043

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008810 based on ALL annotations
The top 100 of 734 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cellulase activity
4,253.43 100.00 45,831 45,831
cellulose catabolic process
1,353.62 28.00 32,081 100,807
cellulose binding
1,285.63 12.95 8,462 27,996
polysaccharide binding
339.95 4.84 5,000 62,559
polysaccharide catabolic process
210.42 4.53 16,088 325,199
hydrolase activity, acting on glycosyl bonds
80.24 1.87 34,625 1,835,510
glucan catabolic process
110.58 1.76 2,354 90,543
hydrolase activity, hydrolyzing O-glycosyl compounds
76.23 1.75 20,804 1,160,741
carbohydrate metabolic process
35.26 0.82 26,010 3,137,227
mannan endo-1,4-beta-mannosidase activity
103.22 0.81 555 22,869
Totals 219867 92020062
No co-occurrence statistics for GO:0008810 based on MANUAL annotations
The top 49 of 49 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cellulase activity
39,145.42 100.00 33 33
cellulose catabolic process
16,310.60 21.28 10 24
cellulose binding
4,744.90 6.45 4 33
xylan binding
39,145.43 3.03 1 1
galacturonan binding
39,145.43 3.03 1 1
cell wall modification involved in multidimensional cell growth
13,048.48 2.86 1 3
cellulosome
13,048.48 2.86 1 3
glucomannan catabolic process
13,048.48 2.86 1 3
acetylxylan esterase activity
4,893.18 2.50 1 8
cellular bud scar
2,174.75 2.00 1 18
Totals 110 396159

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM 9.5 cellulase activity
2020-10-08 Added SYNONYM 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity
2020-10-08 Deleted SYNONYM 9.5 cellulase activity
2020-10-08 Deleted SYNONYM 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity
2020-10-08 Deleted SYNONYM celludextrinase activity
2020-10-08 Added SYNONYM celludextrinase activity
2011-12-08 Added SYNONYM endoglucanase activity
2011-12-08 Deleted SYNONYM endoglucanase activity
2011-12-08 Deleted SYNONYM beta-1,4-endoglucan hydrolase activity
2011-12-08 Deleted SYNONYM endo-1,4-beta-glucanase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM cellulase activity
2002-02-06 Updated TERM cellulase
2001-04-03 Updated TERM cellulase
2001-03-30 Added TERM cellulase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM 9.5 cellulase activity
2020-10-08 Added SYNONYM 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity
2020-10-08 Deleted SYNONYM 9.5 cellulase activity
2020-10-08 Deleted SYNONYM 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity
2020-10-08 Deleted SYNONYM celludextrinase activity
2020-10-08 Added SYNONYM celludextrinase activity
2011-12-08 Added SYNONYM endoglucanase activity
2011-12-08 Deleted SYNONYM endoglucanase activity
2011-12-08 Deleted SYNONYM beta-1,4-endoglucan hydrolase activity
2011-12-08 Deleted SYNONYM endo-1,4-beta-glucanase activity
2011-12-08 Deleted SYNONYM endo-1,4-beta-D-glucanohydrolase activity
2011-12-08 Deleted SYNONYM endo-1,4-beta-D-glucanase activity
2011-12-08 Added SYNONYM endo-1,4-beta-D-glucanase activity
2011-12-08 Added SYNONYM endo-1,4-beta-glucanase activity
2011-12-08 Added SYNONYM beta-1,4-endoglucan hydrolase activity
2011-12-08 Added SYNONYM endo-1,4-beta-D-glucanohydrolase activity
2011-10-28 Deleted DEFINITION Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
2011-10-28 Added DEFINITION Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
2011-09-25 Deleted SYNONYM alkali cellulase activity
2011-09-25 Added SYNONYM alkali cellulase activity
2011-09-25 Added SYNONYM avicelase activity
2011-09-25 Deleted SYNONYM avicelase activity
2008-05-13 Added DEFINITION Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
2008-05-12 Deleted DEFINITION Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
2007-11-08 Added SYNONYM celluase A
2007-11-08 Added SYNONYM cellulase A 3
2007-11-08 Added SYNONYM 9.5 cellulase activity
2007-11-08 Added SYNONYM 1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity
2007-11-08 Added SYNONYM cellulosin AP
2007-11-08 Added SYNONYM endoglucanase D
2007-11-08 Added SYNONYM pancellase SS
2007-11-08 Added SYNONYM alkali cellulase activity
2007-09-06 Deleted SYNONYM endo-1,4-beta glucanase
2007-09-06 Deleted SYNONYM endoglucanase
2007-09-06 Added SYNONYM avicelase activity
2007-09-06 Added SYNONYM beta-1,4-endoglucan hydrolase activity
2007-09-06 Added SYNONYM beta-1,4-glucanase activity
2007-09-06 Added SYNONYM carboxymethyl cellulase activity
2007-09-06 Added SYNONYM celludextrinase activity
2007-09-06 Added SYNONYM endo-1,4-beta-D-glucanase activity
2007-09-06 Added SYNONYM endo-1,4-beta-D-glucanohydrolase activity
2007-09-06 Added SYNONYM endo-1,4-beta-glucanase activity
2007-09-06 Added SYNONYM endoglucanase activity
2007-08-09 Deleted SYNONYM endo-1,4-beta glucanase
2007-08-09 Deleted SYNONYM endoglucanase
2007-08-09 Added SYNONYM endoglucanase
2007-08-09 Added SYNONYM endo-1,4-beta glucanase
2004-04-19 Added SYNONYM endoglucanase
2004-04-19 Added SYNONYM endo-1,4-beta glucanase
2004-04-16 Deleted SYNONYM endo-1,4-beta glucanase
2004-04-16 Deleted SYNONYM endoglucanase
2003-10-27 Added SYNONYM endo-1,4-beta glucanase
2003-10-27 Added SYNONYM endoglucanase
2003-08-18 Deleted SYNONYM endo-1,4-beta glucanase
2003-08-18 Deleted SYNONYM endoglucanase
2002-11-27 Added DEFINITION Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
2001-03-30 Added SYNONYM endo-1,4-beta glucanase
2001-03-30 Added SYNONYM endoglucanase
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:RXN-2043
2009-05-21 Deleted XREF MetaCyc:3.2.1.4-RXN
2003-10-27 Added XREF MetaCyc:3.2.1.4-RXN
2001-03-30 Added XREF EC:3.2.1.4
Timestamp Action Category Detail
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