GO:0008817
JSON
corrinoid adenosyltransferase activity
Molecular Function
Definition (GO:0008817 GONUTS page)
Catalysis of the reaction: 2 ATP + 2 corrinoid + reduced [electron-transfer flavoprotein] = 2 adenosylcorrinoid + 3 H+ + oxidized [electron-transfer flavoprotein] + 2 triphosphate. The corrinoid can be cob(II)yrinate a,c diamide, cob(II)inamide or cob(II)alamin. PMID:19933577 PMID:5946606
Secondary IDs
GO:0043784
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
cob(I)yrinic acid a,c-diamide adenosyltransferase activity | narrow |
cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity | narrow |
aquacob(I)alamin adenosyltransferase activity | narrow |
ATP:cob(I)alamin Co-beta-adenosyltransferase activity | narrow |
ATP:corrinoid adenosyltransferase activity | related |
cob(I)alamin adenosyltransferase activity | narrow |
ATP:cob(I)alamin cobeta-adenosyltransferase activity | related |
aquocob(I)alamin vitamin B12s adenosyltransferase activity | narrow |
ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity | narrow |
cob(II)yrinic acid a,c-diamide reductase activity | narrow |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.5.1.17 | |
InterPro | IPR003724 | ATP:cob(I)alamin adenosyltransferase CobA/CobO/BtuR |
InterPro | IPR009194 | Corrinoid adenosyltransferase EutT |
KEGG_REACTION | R05218 | |
MetaCyc | BTUR2-RXN | |
MetaCyc | RXN-19335 | |
MetaCyc | RXN-19339 | |
RHEA | 11528 | |
RHEA | 14725 | |
RHEA | 28671 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008817 based on ALL annotations
The top 100 of 125 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
corrinoid adenosyltransferase activity
|
3,473.98 | 100.00 | 56,114 | 56,114 |
cobalamin biosynthetic process
|
491.01 | 13.94 | 51,103 | 361,559 |
porphyrin-containing compound biosynthetic process
|
82.55 | 2.11 | 8,817 | 371,042 |
ethanolamine metabolic process
|
636.46 | 2.02 | 1,246 | 6,801 |
transferase activity
|
25.51 | 0.73 | 53,131 | 7,234,614 |
ATP binding
|
10.32 | 0.30 | 56,010 | 18,856,705 |
cobalamin metabolic process
|
78.08 | 0.15 | 93 | 4,138 |
cytoplasm
|
1.21 | 0.03 | 8,818 | 25,285,876 |
cobalamin binding
|
1.21 | 0.03 | 95 | 272,906 |
transferase activity, transferring alkyl or aryl (other than methyl) groups
|
0.98 | 0.02 | 94 | 332,859 |
Totals | 235948 | 181145306 |
No co-occurrence statistics for GO:0008817 based on MANUAL annotations
The top 11 of 11 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
corrinoid adenosyltransferase activity
|
20,835.47 | 100.00 | 62 | 62 |
cobalamin metabolic process
|
2,016.34 | 5.08 | 6 | 62 |
transferase activity, transferring alkyl or aryl (other than methyl) groups
|
1,562.66 | 4.41 | 6 | 80 |
cobalamin binding
|
984.35 | 3.28 | 6 | 127 |
aerobic cobalamin biosynthetic process
|
20,835.47 | 1.61 | 1 | 1 |
propanediol degradation polyhedral organelle
|
1,157.53 | 1.27 | 1 | 18 |
cobalamin biosynthetic process
|
548.30 | 1.01 | 1 | 38 |
mitochondrial matrix
|
5.31 | 0.03 | 1 | 3,923 |
biological_process
|
0.94 | 0.00 | 3 | 66,439 |
mitochondrion
|
0.91 | 0.00 | 2 | 45,791 |
Totals | 90 | 158358 |
Change Log
- All changes
- All changes
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-06 | Added | XREF | Reactome:R-HSA-3159253 |
2024-11-05 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-11-03 | Added | XREF | Reactome:R-HSA-3159253 |
2024-11-02 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-11-01 | Added | XREF | Reactome:R-HSA-3159253 |
2024-10-26 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-10-09 | Added | XREF | Reactome:R-HSA-3159253 |
2024-10-08 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-09-21 | Added | XREF | Reactome:R-HSA-3159253 |
2024-09-20 | Deleted | XREF | Reactome:R-HSA-3159253 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-10-02 | Updated | TERM | corrinoid adenosyltransferase activity |
2004-07-08 | Updated | TERM | cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
2004-07-04 | Updated | TERM | cob(I)alamin adenosyltransferase activity |
2004-06-27 | Updated | TERM | cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
2003-03-19 | Updated | TERM | cob(I)alamin adenosyltransferase activity |
2002-02-06 | Updated | TERM | cob(I)alamin adenosyltransferase |
2001-04-03 | Updated | TERM | cob(I)alamin adenosyltransferase |
2001-03-30 | Added | TERM | cob(I)alamin adenosyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-10-02 | Added | DEFINITION | Catalysis of the reaction: 2 ATP + 2 corrinoid + reduced [electron-transfer flavoprotein] = 2 adenosylcorrinoid + 3 H+ + oxidized [electron-transfer flavoprotein] + 2 triphosphate. The corrinoid can be cob(II)yrinate a,c diamide, cob(II)inamide or cob(II)alamin. |
2022-10-02 | Added | SYNONYM | aquocob(I)alamin vitamin B12s adenosyltransferase activity |
2022-10-02 | Added | SYNONYM | ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity |
2022-10-02 | Added | SYNONYM | cob(I)alamin adenosyltransferase activity |
2022-10-02 | Added | SYNONYM | cob(II)yrinic acid a,c-diamide reductase activity |
2022-10-02 | Added | SYNONYM | cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
2022-10-02 | Added | SYNONYM | cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity |
2022-10-02 | Added | SYNONYM | aquacob(I)alamin adenosyltransferase activity |
2022-10-02 | Added | SYNONYM | ATP:cob(I)alamin Co-beta-adenosyltransferase activity |
2022-10-02 | Deleted | SYNONYM | ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity |
2022-10-02 | Deleted | SYNONYM | aquacob(I)alamin adenosyltransferase activity |
2022-10-02 | Deleted | SYNONYM | ATP:cob(I)alamin Co-beta-adenosyltransferase activity |
2022-10-02 | Deleted | SYNONYM | aquocob(I)alamin vitamin B12s adenosyltransferase activity |
2022-10-02 | Deleted | SYNONYM | CobA |
2022-10-02 | Deleted | SYNONYM | cob(I)alamin adenosyltransferase activity |
2022-10-02 | Deleted | DEFINITION | Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin. |
2020-10-08 | Deleted | SYNONYM | ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:cob(I)alamin cobeta-adenosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:cob(I)alamin Co-beta-adenosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:corrinoid adenosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | vitamin B12s adenosyltransferase activity |
2020-10-08 | Deleted | SYNONYM | aquacob(I)alamin adenosyltransferase activity |
2020-10-08 | Added | SYNONYM | ATP:corrinoid adenosyltransferase activity |
2020-10-08 | Added | SYNONYM | vitamin B12s adenosyltransferase activity |
2020-10-08 | Added | SYNONYM | ATP:cob(I)alamin cobeta-adenosyltransferase activity |
2020-10-08 | Added | SYNONYM | aquacob(I)alamin adenosyltransferase activity |
2020-10-08 | Added | SYNONYM | ATP:cob(I)alamin Co-beta-adenosyltransferase activity |
2020-10-08 | Added | SYNONYM | ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin. |
2007-11-08 | Added | SYNONYM | ATP:cob(I)alamin cobeta-adenosyltransferase activity |
2007-11-08 | Added | SYNONYM | ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity |
2007-11-08 | Added | SYNONYM | CobA |
2007-11-08 | Added | SYNONYM | vitamin B12s adenosyltransferase activity |
2007-09-06 | Added | SYNONYM | aquocob(I)alamin vitamin B12s adenosyltransferase activity |
2007-09-06 | Added | SYNONYM | aquacob(I)alamin adenosyltransferase activity |
2007-09-06 | Added | SYNONYM | ATP:cob(I)alamin Co-beta-adenosyltransferase activity |
2007-09-06 | Added | SYNONYM | ATP:corrinoid adenosyltransferase activity |
2007-08-09 | Deleted | SYNONYM | cob(I)alamin adenosyltransferase activity |
2007-08-09 | Added | SYNONYM | cob(I)alamin adenosyltransferase activity |
2004-07-08 | Added | SYNONYM | cob(I)alamin adenosyltransferase activity |
2004-07-04 | Deleted | SYNONYM | cob(I)alamin adenosyltransferase activity |
2004-06-27 | Added | SYNONYM | cob(I)alamin adenosyltransferase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-06 | Added | XREF | Reactome:R-HSA-3159253 |
2024-11-05 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-11-03 | Added | XREF | Reactome:R-HSA-3159253 |
2024-11-02 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-11-01 | Added | XREF | Reactome:R-HSA-3159253 |
2024-10-26 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-10-09 | Added | XREF | Reactome:R-HSA-3159253 |
2024-10-08 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-09-21 | Added | XREF | Reactome:R-HSA-3159253 |
2024-09-20 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-09-19 | Added | XREF | Reactome:R-HSA-3159253 |
2024-09-13 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-09-10 | Added | XREF | Reactome:R-HSA-3159253 |
2024-09-08 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-09-07 | Added | XREF | Reactome:R-HSA-3159253 |
2024-09-06 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-09-05 | Added | XREF | Reactome:R-HSA-3159253 |
2024-09-02 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-08-20 | Added | XREF | Reactome:R-HSA-3159253 |
2024-08-16 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-08-15 | Added | XREF | Reactome:R-HSA-3159253 |
2024-08-08 | Added | XREF | Reactome:R-HSA-3159253 |
2024-08-08 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-08-06 | Deleted | XREF | MetaCyc:R343-RXN |
2024-08-06 | Added | XREF | MetaCyc:RXN-19339 |
2024-08-06 | Added | XREF | MetaCyc:RXN-19335 |
2024-08-06 | Added | XREF | MetaCyc:BTUR2-RXN |
2024-08-06 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-08-06 | Deleted | XREF | MetaCyc:COBALADENOSYLTRANS-RXN |
2024-08-05 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-28 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-27 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-26 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-25 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-20 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-19 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-18 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-14 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-11 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-10 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-09 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-06 | Added | XREF | Reactome:R-HSA-3159253 |
2024-07-04 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-07-03 | Added | XREF | Reactome:R-HSA-3159253 |
2024-06-30 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-06-29 | Added | XREF | Reactome:R-HSA-3159253 |
2024-06-28 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-06-27 | Added | XREF | Reactome:R-HSA-3159253 |
2024-06-26 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-06-23 | Added | XREF | Reactome:R-HSA-3159253 |
2024-06-20 | Deleted | XREF | Reactome:R-HSA-3159253 |
2024-06-19 | Added | XREF | Reactome:R-HSA-3159253 |
2023-04-02 | Deleted | XREF | Reactome:R-HSA-3159253 |
2022-10-02 | Added | XREF | RHEA:28671 |
2022-10-02 | Added | XREF | RHEA:11528 |
2022-10-02 | Added | XREF | KEGG_REACTION:R05218 |
2022-10-02 | Added | XREF | MetaCyc:R343-RXN |
2019-05-04 | Added | XREF | Reactome:R-HSA-3322125 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-3322125 |
2019-04-29 | Added | XREF | Reactome:R-HSA-3322125 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-3322125 |
2019-04-27 | Added | XREF | Reactome:R-HSA-3322125 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-3322125 |
2019-04-01 | Added | XREF | Reactome:R-HSA-3159253 |
2019-04-01 | Added | XREF | Reactome:R-HSA-3322125 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-3159253 |
2018-12-11 | Added | XREF | reactome:R-HSA-3159253 |
2018-07-13 | Added | XREF | RHEA:14725 |
2018-07-13 | Deleted | XREF | RHEA:14728 |
2012-09-14 | Added | XREF | RHEA:14728 |
2003-10-27 | Added | XREF | MetaCyc:COBALADENOSYLTRANS-RXN |
2001-03-30 | Added | XREF | EC:2.5.1.17 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-10-02 | Added | SECONDARY | GO:0043784 (cob(II)yrinic acid a,c-diamide reductase activity) |
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