This term is obsolete.

GO:0008837 JSON

diaminopimelate epimerase activity

Molecular Function

Definition (GO:0008837 GONUTS page)

Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.

40,686 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
LL-2,6-diaminoheptanedioate 2-epimerase activity related

Ancestor Chart

Ancestor chart for GO:0008837
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 5.1.1.7
InterPro IPR001653 Diaminopimelate epimerase, DapF
InterPro IPR018510 Diaminopimelate epimerase, active site
KEGG_REACTION R02735
MetaCyc DIAMINOPIMEPIM-RXN
RHEA 15393

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57609 (2S,6S)-2,6-diaminopimelic acid dizwitterion
has_participant CHEBI CHEBI:57791 meso-2,6-diaminopimelic acid dizwitterion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008837 based on ALL annotations
The top 100 of 188 co-occurring terms
Co-occurring Term PR S% #Together #Compared
diaminopimelate epimerase activity
4,802.75 100.00 40,589 40,589
lysine biosynthetic process
552.53 11.40 37,722 327,889
lysine biosynthetic process via diaminopimelate
519.10 10.81 40,496 374,673
isomerase activity
61.10 1.27 40,492 3,183,067
cytosol
14.02 0.29 40,063 13,724,995
carbamoyl-phosphate synthase (ammonia) activity
20.96 0.17 114 26,123
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
10.69 0.17 284 127,639
cytoplasm
7.18 0.15 37,793 25,285,876
'de novo' UMP biosynthetic process
4.08 0.07 250 294,019
L-arginine biosynthetic process
3.17 0.06 267 404,701
Totals 240106 107110729
No co-occurrence statistics for GO:0008837 based on MANUAL annotations
The top 7 of 7 co-occurring terms
Co-occurring Term PR S% #Together #Compared
diaminopimelate epimerase activity
14,041.29 100.00 92 92
lysine biosynthetic process via diaminopimelate
4,663.53 33.21 92 277
enzyme activator activity
34.76 0.20 1 404
cytosol
15.34 0.11 92 84,217
protein homodimerization activity
2.64 0.02 1 5,319
protein binding
0.34 0.00 1 41,817
plasma membrane
0.11 0.00 1 131,928
Totals 280 264054

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM LL-2,6-diaminoheptanedioate 2-epimerase activity
2020-10-08 Deleted SYNONYM LL-2,6-diaminoheptanedioate 2-epimerase activity
2019-06-20 Deleted XREF KEGG:R02735
2019-06-20 Added XREF KEGG_REACTION:R02735
2018-07-13 Deleted XREF RHEA:15396
2018-07-13 Added XREF RHEA:15393
2012-05-31 Added RELATION has part GO:0033362 (lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway)
2010-10-11 Deleted DEFINITION Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate.
2010-10-11 Added DEFINITION Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.
2010-10-11 Added XREF RHEA:15396
Timestamp Action Category Detail
2003-03-19 Updated TERM diaminopimelate epimerase activity
2002-02-06 Updated TERM diaminopimelate epimerase
2001-04-03 Updated TERM diaminopimelate epimerase
2001-03-30 Added TERM diaminopimelate epimerase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM LL-2,6-diaminoheptanedioate 2-epimerase activity
2020-10-08 Deleted SYNONYM LL-2,6-diaminoheptanedioate 2-epimerase activity
2010-10-11 Deleted DEFINITION Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate.
2010-10-11 Added DEFINITION Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.
2008-05-13 Added DEFINITION Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate.
2007-11-08 Added SYNONYM LL-2,6-diaminoheptanedioate 2-epimerase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate.
Timestamp Action Category Detail
2012-05-31 Added RELATION has part GO:0033362 (lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway)
2009-03-30 Deleted RELATION is a GO:0016855 (racemase and epimerase activity, acting on amino acids and derivatives)
2009-03-30 Added RELATION is a GO:0047661 (amino-acid racemase activity)
2008-04-01 Updated RELATION is a GO:0016855 (racemase and epimerase activity, acting on amino acids and derivatives)
Timestamp Action Category Detail
2019-06-20 Deleted XREF KEGG:R02735
2019-06-20 Added XREF KEGG_REACTION:R02735
2018-07-13 Deleted XREF RHEA:15396
2018-07-13 Added XREF RHEA:15393
2010-10-11 Added XREF RHEA:15396
2010-10-11 Added XREF KEGG:R02735
2003-10-27 Added XREF MetaCyc:DIAMINOPIMEPIM-RXN
2001-03-30 Added XREF EC:5.1.1.7
Timestamp Action Category Detail
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