GO:0008837
JSON
diaminopimelate epimerase activity
Molecular Function
Definition (GO:0008837 GONUTS page)
Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
LL-2,6-diaminoheptanedioate 2-epimerase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.1.1.7 | |
InterPro | IPR001653 | Diaminopimelate epimerase, DapF |
InterPro | IPR018510 | Diaminopimelate epimerase, active site |
KEGG_REACTION | R02735 | |
MetaCyc | DIAMINOPIMEPIM-RXN | |
RHEA | 15393 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57609 | (2S,6S)-2,6-diaminopimelic acid dizwitterion |
has_participant | CHEBI | CHEBI:57791 | meso-2,6-diaminopimelic acid dizwitterion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008837 based on ALL annotations
The top 100 of 188 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
diaminopimelate epimerase activity
|
4,802.75 | 100.00 | 40,589 | 40,589 |
lysine biosynthetic process
|
552.53 | 11.40 | 37,722 | 327,889 |
lysine biosynthetic process via diaminopimelate
|
519.10 | 10.81 | 40,496 | 374,673 |
isomerase activity
|
61.10 | 1.27 | 40,492 | 3,183,067 |
cytosol
|
14.02 | 0.29 | 40,063 | 13,724,995 |
carbamoyl-phosphate synthase (ammonia) activity
|
20.96 | 0.17 | 114 | 26,123 |
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
|
10.69 | 0.17 | 284 | 127,639 |
cytoplasm
|
7.18 | 0.15 | 37,793 | 25,285,876 |
'de novo' UMP biosynthetic process
|
4.08 | 0.07 | 250 | 294,019 |
L-arginine biosynthetic process
|
3.17 | 0.06 | 267 | 404,701 |
Totals | 240106 | 107110729 |
No co-occurrence statistics for GO:0008837 based on MANUAL annotations
The top 7 of 7 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
diaminopimelate epimerase activity
|
14,041.29 | 100.00 | 92 | 92 |
lysine biosynthetic process via diaminopimelate
|
4,663.53 | 33.21 | 92 | 277 |
enzyme activator activity
|
34.76 | 0.20 | 1 | 404 |
cytosol
|
15.34 | 0.11 | 92 | 84,217 |
protein homodimerization activity
|
2.64 | 0.02 | 1 | 5,319 |
protein binding
|
0.34 | 0.00 | 1 | 41,817 |
plasma membrane
|
0.11 | 0.00 | 1 | 131,928 |
Totals | 280 | 264054 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | LL-2,6-diaminoheptanedioate 2-epimerase activity |
2020-10-08 | Deleted | SYNONYM | LL-2,6-diaminoheptanedioate 2-epimerase activity |
2019-06-20 | Deleted | XREF | KEGG:R02735 |
2019-06-20 | Added | XREF | KEGG_REACTION:R02735 |
2018-07-13 | Deleted | XREF | RHEA:15396 |
2018-07-13 | Added | XREF | RHEA:15393 |
2012-05-31 | Added | RELATION | has part GO:0033362 (lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway) |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate. |
2010-10-11 | Added | XREF | RHEA:15396 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | diaminopimelate epimerase activity |
2002-02-06 | Updated | TERM | diaminopimelate epimerase |
2001-04-03 | Updated | TERM | diaminopimelate epimerase |
2001-03-30 | Added | TERM | diaminopimelate epimerase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | LL-2,6-diaminoheptanedioate 2-epimerase activity |
2020-10-08 | Deleted | SYNONYM | LL-2,6-diaminoheptanedioate 2-epimerase activity |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. |
2007-11-08 | Added | SYNONYM | LL-2,6-diaminoheptanedioate 2-epimerase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-05-31 | Added | RELATION | has part GO:0033362 (lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway) |
2009-03-30 | Deleted | RELATION | is a GO:0016855 (racemase and epimerase activity, acting on amino acids and derivatives) |
2009-03-30 | Added | RELATION | is a GO:0047661 (amino-acid racemase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016855 (racemase and epimerase activity, acting on amino acids and derivatives) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R02735 |
2019-06-20 | Added | XREF | KEGG_REACTION:R02735 |
2018-07-13 | Deleted | XREF | RHEA:15396 |
2018-07-13 | Added | XREF | RHEA:15393 |
2010-10-11 | Added | XREF | RHEA:15396 |
2010-10-11 | Added | XREF | KEGG:R02735 |
2003-10-27 | Added | XREF | MetaCyc:DIAMINOPIMEPIM-RXN |
2001-03-30 | Added | XREF | EC:5.1.1.7 |
Timestamp | Action | Category | Detail |
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