This term is obsolete.

GO:0008865 JSON

fructokinase activity

Molecular Function

Definition (GO:0008865 GONUTS page)

Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.

32,154 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
D-fructose(D-mannose)kinase activity related
ATP:D-fructose 6-phosphotransferase activity related
fructokinase (phosphorylating) related
D-fructokinase activity related

Ancestor Chart

Ancestor chart for GO:0008865
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A1L8END5 8355 A0A1L8END5_XENLA GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1L8EV37 8355 A0A1L8EV37_XENLA GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8I3Q0M1 9615 A0A8I3Q0M1_CANLF GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8J0TR01 8355 A0A8J0TR01_XENLA GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8J0TZJ2 8355 A0A8J0TZJ2_XENLA GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8M2B232 7955 A0A8M2B232_DANRE GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
EC 2.7.1.4
MetaCyc FRUCTOKINASE-RXN
RHEA 16125

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:61527 D-fructofuranose 6-phosphate(2-)
has_participant CHEBI CHEBI:456216 ADP(3-)
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:37721 D-fructofuranose

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008865 based on ALL annotations
The top 100 of 374 co-occurring terms
Co-occurring Term PR S% #Together #Compared
fructokinase activity
6,230.70 100.00 31,803 31,803
intracellular glucose homeostasis
5,296.98 56.79 20,071 23,609
hexokinase activity
4,792.65 55.45 21,153 27,500
D-glucose binding
3,178.46 39.29 20,070 39,343
glucokinase activity
2,588.25 33.38 20,017 48,187
mannokinase activity
6,223.41 24.16 7,686 7,695
glucose 6-phosphate metabolic process
1,177.06 17.00 20,013 105,938
hexose metabolic process
1,699.87 16.39 9,256 33,927
carbohydrate kinase activity
4,533.23 11.61 3,859 5,304
fructose metabolic process
960.49 10.89 8,608 55,840
Totals 360609 52632673
No co-occurrence statistics for GO:0008865 based on MANUAL annotations
The top 100 of 154 co-occurring terms
Co-occurring Term PR S% #Together #Compared
fructokinase activity
2,145.19 100.00 658 658
glucokinase activity
2,028.71 61.29 418 442
intracellular glucose homeostasis
1,625.02 51.21 403 532
glucose 6-phosphate metabolic process
1,197.31 41.59 408 731
fructose metabolic process
776.87 22.38 243 671
glucose metabolic process
505.41 20.54 405 1,719
mannokinase activity
2,145.19 14.29 94 94
glycolytic process
251.24 10.90 403 3,441
mannose metabolic process
398.66 4.99 42 226
hexokinase activity
1,705.15 4.65 31 39
Totals 4378 169343

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM D-fructose(D-mannose)kinase activity
2020-10-08 Added SYNONYM fructokinase (phosphorylating)
2020-10-08 Deleted SYNONYM D-fructokinase activity
2020-10-08 Added SYNONYM ATP:D-fructose 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM ATP:D-fructose 6-phosphotransferase activity
2020-10-08 Added SYNONYM D-fructokinase activity
2020-10-08 Deleted SYNONYM D-fructose(D-mannose)kinase activity
2020-10-08 Deleted SYNONYM fructokinase (phosphorylating)
2018-07-13 Added XREF RHEA:16125
2018-07-13 Deleted XREF RHEA:16128
Timestamp Action Category Detail
2003-03-19 Updated TERM fructokinase activity
2002-02-06 Updated TERM fructokinase
2001-04-03 Updated TERM fructokinase
2001-03-30 Added TERM fructokinase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM D-fructose(D-mannose)kinase activity
2020-10-08 Added SYNONYM fructokinase (phosphorylating)
2020-10-08 Deleted SYNONYM D-fructokinase activity
2020-10-08 Added SYNONYM ATP:D-fructose 6-phosphotransferase activity
2020-10-08 Deleted SYNONYM ATP:D-fructose 6-phosphotransferase activity
2020-10-08 Added SYNONYM D-fructokinase activity
2020-10-08 Deleted SYNONYM D-fructose(D-mannose)kinase activity
2020-10-08 Deleted SYNONYM fructokinase (phosphorylating)
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.
2007-11-08 Added SYNONYM fructokinase (phosphorylating)
2007-11-08 Added SYNONYM D-fructose(D-mannose)kinase activity
2007-11-08 Added SYNONYM ATP:D-fructose 6-phosphotransferase activity
2007-09-06 Added SYNONYM D-fructokinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.
Timestamp Action Category Detail
2017-05-01 Added RELATION has part GO:0061616 (glycolytic process from fructose through fructose-6-phosphate)
2015-07-26 Added RELATION has part GO:0019574 (sucrose catabolic process via 3'-ketosucrose)
2015-07-26 Added RELATION has part GO:0036008 (sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate)
2015-06-13 Added RELATION has part GO:0061705 (sucrose catabolic process to fructose-6-phosphate through glucose and fructose)
2014-05-07 Deleted RELATION has part GO:0061616 (glycolytic process from fructose through fructose-6-phosphate)
2014-04-10 Added RELATION has part GO:0061616 (glycolytic process from fructose through fructose-6-phosphate)
2008-04-01 Updated RELATION is a GO:0004396 (hexokinase activity)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:16125
2018-07-13 Deleted XREF RHEA:16128
2011-09-16 Added XREF RHEA:16128
2003-10-27 Added XREF MetaCyc:FRUCTOKINASE-RXN
2001-03-30 Added XREF EC:2.7.1.4
Timestamp Action Category Detail
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