GO:0008865
JSON
fructokinase activity
Molecular Function
Definition (GO:0008865 GONUTS page)
Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
D-fructokinase activity | related |
ATP:D-fructose 6-phosphotransferase activity | related |
fructokinase (phosphorylating) | related |
D-fructose(D-mannose)kinase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A1L8END5 | 8355 | A0A1L8END5_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8EV37 | 8355 | A0A1L8EV37_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I3Q0M1 | 9615 | A0A8I3Q0M1_CANLF | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I6AKN3 | 10116 | A0A8I6AKN3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ALM9 | 10116 | A0A8I6ALM9_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GLX5 | 10116 | A0A8I6GLX5_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J0TR01 | 8355 | A0A8J0TR01_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8J0TZJ2 | 8355 | A0A8J0TZJ2_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8M2B232 | 7955 | A0A8M2B232_DANRE | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.1.4 | |
MetaCyc | FRUCTOKINASE-RXN | |
RHEA | 16125 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:456216 | ADP(3-) |
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:61527 | D-fructofuranose 6-phosphate(2-) |
has_participant | CHEBI | CHEBI:37721 | D-fructofuranose |
has_participant | CHEBI | CHEBI:15378 | hydron |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008865 based on ALL annotations
The top 100 of 364 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
fructokinase activity
|
6,374.30 | 100.00 | 30,582 | 30,582 |
intracellular glucose homeostasis
|
5,412.00 | 57.49 | 19,583 | 23,065 |
hexokinase activity
|
4,908.48 | 56.24 | 20,671 | 26,844 |
D-glucose binding
|
3,230.29 | 39.45 | 19,582 | 38,641 |
glucokinase activity
|
2,643.19 | 33.60 | 19,541 | 47,125 |
mannokinase activity
|
6,365.18 | 25.10 | 7,679 | 7,690 |
hexose metabolic process
|
1,778.15 | 17.06 | 9,328 | 33,439 |
glucose 6-phosphate metabolic process
|
1,197.82 | 16.99 | 19,537 | 103,968 |
carbohydrate kinase activity
|
4,654.94 | 11.72 | 3,747 | 5,131 |
carbohydrate phosphorylation
|
677.73 | 10.63 | 30,582 | 287,637 |
Totals | 347078 | 55894806 |
No co-occurrence statistics for GO:0008865 based on MANUAL annotations
The top 100 of 158 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
fructokinase activity
|
2,246.61 | 100.00 | 575 | 575 |
glucokinase activity
|
2,104.78 | 61.83 | 371 | 396 |
intracellular glucose homeostasis
|
1,662.77 | 50.86 | 356 | 481 |
glucose 6-phosphate metabolic process
|
1,234.44 | 41.45 | 361 | 657 |
fructose metabolic process
|
763.63 | 21.19 | 207 | 609 |
glucose metabolic process
|
508.40 | 19.90 | 358 | 1,582 |
mannokinase activity
|
2,246.61 | 12.00 | 69 | 69 |
glycolytic process
|
264.57 | 10.98 | 356 | 3,023 |
mannose metabolic process
|
447.19 | 5.65 | 42 | 211 |
hexokinase activity
|
1,785.76 | 5.32 | 31 | 39 |
Totals | 3861 | 159477 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | fructokinase (phosphorylating) |
2020-10-08 | Deleted | SYNONYM | D-fructose(D-mannose)kinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:D-fructose 6-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | ATP:D-fructose 6-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | D-fructokinase activity |
2020-10-08 | Added | SYNONYM | fructokinase (phosphorylating) |
2020-10-08 | Deleted | SYNONYM | D-fructokinase activity |
2020-10-08 | Added | SYNONYM | D-fructose(D-mannose)kinase activity |
2018-07-13 | Added | XREF | RHEA:16125 |
2018-07-13 | Deleted | XREF | RHEA:16128 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | fructokinase activity |
2002-02-06 | Updated | TERM | fructokinase |
2001-04-03 | Updated | TERM | fructokinase |
2001-03-30 | Added | TERM | fructokinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | fructokinase (phosphorylating) |
2020-10-08 | Deleted | SYNONYM | D-fructose(D-mannose)kinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:D-fructose 6-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | ATP:D-fructose 6-phosphotransferase activity |
2020-10-08 | Added | SYNONYM | D-fructokinase activity |
2020-10-08 | Added | SYNONYM | fructokinase (phosphorylating) |
2020-10-08 | Deleted | SYNONYM | D-fructokinase activity |
2020-10-08 | Added | SYNONYM | D-fructose(D-mannose)kinase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. |
2007-11-08 | Added | SYNONYM | fructokinase (phosphorylating) |
2007-11-08 | Added | SYNONYM | D-fructose(D-mannose)kinase activity |
2007-11-08 | Added | SYNONYM | ATP:D-fructose 6-phosphotransferase activity |
2007-09-06 | Added | SYNONYM | D-fructokinase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-05-01 | Added | RELATION | has part GO:0061616 (glycolytic process from fructose through fructose-6-phosphate) |
2015-07-26 | Added | RELATION | has part GO:0019574 (sucrose catabolic process via 3'-ketosucrose) |
2015-07-26 | Added | RELATION | has part GO:0036008 (sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate) |
2015-06-13 | Added | RELATION | has part GO:0061705 (sucrose catabolic process to fructose-6-phosphate through glucose and fructose) |
2014-05-07 | Deleted | RELATION | has part GO:0061616 (glycolytic process from fructose through fructose-6-phosphate) |
2014-04-10 | Added | RELATION | has part GO:0061616 (glycolytic process from fructose through fructose-6-phosphate) |
2008-04-01 | Updated | RELATION | is a GO:0004396 (hexokinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:16125 |
2018-07-13 | Deleted | XREF | RHEA:16128 |
2011-09-16 | Added | XREF | RHEA:16128 |
2003-10-27 | Added | XREF | MetaCyc:FRUCTOKINASE-RXN |
2001-03-30 | Added | XREF | EC:2.7.1.4 |
Timestamp | Action | Category | Detail |
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