This term is obsolete.

GO:0008901 JSON

ferredoxin hydrogenase activity

Molecular Function

Definition (GO:0008901 GONUTS page)

Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.

Secondary IDs

GO:0016948, GO:0016949, GO:0016950, GO:0016951

39,263 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
hydrogen:ferredoxin oxidoreductase activity exact
Ni-Fe hydrogenase activity narrow
hydrogenase II related
Ni-Fe-Se hydrogenase activity narrow
nickel-iron hydrogenase activity narrow
nickel-iron-selenium hydrogenase activity narrow
H(2) oxidizing hydrogenase activity broad
H(2) producing hydrogenase activity broad
bidirectional hydrogenase activity broad
hydrogen-lyase activity broad

Ancestor Chart

Ancestor chart for GO:0008901
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008901

Child Term Relationship to
GO:0008901
ferredoxin hydrogenase complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
EC 1.12.7.2
InterPro IPR001821 [NiFe]-hydrogenase, small subunit
InterPro IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase
InterPro IPR008953 Iron hydrogenase, small subunit HydB-type
InterPro IPR013352 Iron hydrogenase, subset
InterPro IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site
InterPro IPR036080 F420-dependent methylenetetrahydromethanopterin dehydrogenase superfamily
MetaCyc HYDROG-RXN
RHEA 17445

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:33738 di-mu-sulfido-diiron(1+)
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:33737 di-mu-sulfido-diiron(2+)
has_participant CHEBI CHEBI:18276 dihydrogen

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008901 based on ALL annotations
The top 100 of 144 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ferredoxin hydrogenase activity
4,965.33 100.00 39,260 39,260
ferredoxin hydrogenase complex
4,965.33 27.82 10,923 10,923
[Ni-Fe] hydrogenase complex
4,960.79 27.81 10,922 10,932
hydrogenase (acceptor) activity
4,488.11 11.06 4,392 4,859
nickel cation binding
482.51 8.78 18,706 192,498
3 iron, 4 sulfur cluster binding
444.78 7.14 10,200 113,869
anaerobic respiration
371.40 6.26 10,921 146,007
cell envelope
113.03 2.20 15,778 693,121
methylenetetrahydromethanopterin dehydrogenase activity
4,829.56 1.90 747 768
iron-sulfur cluster binding
59.59 1.19 19,704 1,641,943
Totals 286754 158991161
No co-occurrence statistics for GO:0008901 based on MANUAL annotations
The top 11 of 11 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ferredoxin hydrogenase activity
215,299.84 100.00 6 6
ferredoxin hydrogenase complex
215,299.84 50.00 3 3
carbazole catabolic process
61,514.24 18.18 2 7
iron-sulfur cluster binding
583.47 0.27 1 369
cytosolic [4Fe-4S] assembly targeting complex
539.60 0.25 1 399
protein maturation by [4Fe-4S] cluster transfer
434.95 0.20 1 495
2 iron, 2 sulfur cluster binding
392.17 0.18 2 1,098
proton motive force-driven ATP synthesis
382.42 0.18 3 1,689
iron-sulfur cluster assembly
110.81 0.05 1 1,943
cytosol
2.56 0.00 1 84,217
Totals 22 282502

Change Log

Timestamp Action Category Detail
2024-07-16 Deleted XREF UM-BBD_enzymeID:e0418
2020-10-08 Added SYNONYM hydrogenase (ferredoxin) activity
2020-10-08 Deleted SYNONYM hydrogenase (ferredoxin) activity
2020-06-22 Added XREF RHEA:17445
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
2008-04-01 Updated RELATION is a GO:0016699 (oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor)
2008-03-10 Added SECONDARY GO:0016951 (nickel-iron-selenium hydrogenase activity)
2008-03-10 Added SECONDARY GO:0016950 (nickel-iron hydrogenase activity)
2008-03-10 Added SECONDARY GO:0016949 (nickel hydrogenase activity)
Timestamp Action Category Detail
2003-11-08 Updated TERM ferredoxin hydrogenase activity
2003-03-19 Updated TERM hydrogenase activity
2002-02-06 Updated TERM hydrogenase
2001-04-03 Updated TERM hydrogenase
2001-03-30 Added TERM hydrogenase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM hydrogenase (ferredoxin) activity
2020-10-08 Deleted SYNONYM hydrogenase (ferredoxin) activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
2008-03-10 Added SYNONYM nickel-iron-selenium hydrogenase activity
2008-03-10 Added SYNONYM nickel-iron hydrogenase activity
2008-03-10 Added SYNONYM nickel hydrogenase activity
2008-03-10 Added SYNONYM iron-only hydrogenase activity
2008-03-10 Added SYNONYM iron hydrogenase activity
2008-03-10 Added SYNONYM Ni-Fe-Se hydrogenase activity
2008-03-10 Added SYNONYM Ni-Fe hydrogenase activity
2008-03-10 Deleted SYNONYM 1.18.99.1
2007-11-08 Added SYNONYM hydrogen:ferredoxin oxidoreductase activity
2007-11-08 Deleted SYNONYM [Fe] hydrogenase
2007-11-08 Deleted SYNONYM hydrogen:ferredoxin oxidoreductase
2007-11-08 Added SYNONYM [Fe] hydrogenase activity
2007-09-06 Added SYNONYM H(2) producing hydrogenase activity
2007-09-06 Added SYNONYM H(2) oxidizing hydrogenase activity
2007-09-06 Deleted SYNONYM bidirectional hydrogenase
2007-09-06 Deleted SYNONYM hydrogen-lyase
2007-09-06 Deleted SYNONYM hydrogenase (ferredoxin)
2007-09-06 Deleted SYNONYM hydrogenlyase
2007-09-06 Added SYNONYM uptake hydrogenase activity
2007-09-06 Added SYNONYM hydrogenlyase activity
2007-09-06 Added SYNONYM hydrogenase (ferredoxin) activity
2007-09-06 Deleted SYNONYM uptake hydrogenase
2007-09-06 Added SYNONYM bidirectional hydrogenase activity
2007-09-06 Added SYNONYM hydrogen-lyase activity
2007-08-09 Added SYNONYM [Fe] hydrogenase
2007-08-09 Added SYNONYM [Fe] hydrogenase gamma
2007-08-09 Added SYNONYM bidirectional hydrogenase
2007-08-09 Added SYNONYM hydrogen-lyase
2007-08-09 Added SYNONYM hydrogen:ferredoxin oxidoreductase
2007-08-09 Added SYNONYM hydrogenase (ferredoxin)
2007-08-09 Added SYNONYM hydrogenase I
2007-08-09 Added SYNONYM hydrogenase II
2007-08-09 Added SYNONYM hydrogenase activity
2007-08-09 Added SYNONYM hydrogenlyase
2007-08-09 Added SYNONYM uptake hydrogenase
2007-08-09 Deleted SYNONYM hydrogenase activity
2007-08-09 Deleted SYNONYM 1.18.99.1
2007-08-09 Deleted SYNONYM H2 oxidizing hydrogenase
2007-08-09 Deleted SYNONYM H2 producing hydrogenase
2007-08-09 Deleted SYNONYM [Fe] hydrogenase
2007-08-09 Deleted SYNONYM [Fe] hydrogenase gamma
2007-08-09 Deleted SYNONYM bidirectional hydrogenase
2007-08-09 Deleted SYNONYM hydrogen-lyase
2007-08-09 Deleted SYNONYM hydrogen:ferredoxin oxidoreductase
2007-08-09 Deleted SYNONYM hydrogenase (ferredoxin)
2007-08-09 Deleted SYNONYM hydrogenase I
2007-08-09 Deleted SYNONYM hydrogenase II
2007-08-09 Deleted SYNONYM hydrogenlyase
2007-08-09 Deleted SYNONYM uptake hydrogenase
2007-08-09 Added SYNONYM 1.18.99.1
2007-08-09 Added SYNONYM H2 oxidizing hydrogenase
2007-08-09 Added SYNONYM H2 producing hydrogenase
2007-08-05 Added SYNONYM H2 oxidizing hydrogenase
2007-08-05 Added SYNONYM hydrogenase I
2007-08-05 Added SYNONYM hydrogenase (ferredoxin)
2007-08-05 Added SYNONYM hydrogen:ferredoxin oxidoreductase
2007-08-05 Added SYNONYM hydrogen-lyase
2007-08-05 Added SYNONYM bidirectional hydrogenase
2007-08-05 Added SYNONYM uptake hydrogenase
2007-08-05 Added SYNONYM hydrogenlyase
2007-08-05 Added SYNONYM 1.18.99.1
2007-08-05 Added SYNONYM hydrogenase II
2007-08-05 Added SYNONYM H2 producing hydrogenase
2007-08-05 Added SYNONYM [Fe] hydrogenase
2007-08-05 Added SYNONYM [Fe] hydrogenase gamma
2004-04-19 Added SYNONYM hydrogenase activity
2004-04-16 Deleted SYNONYM hydrogenase activity
2003-11-08 Added SYNONYM hydrogenase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016699 (oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor)
Timestamp Action Category Detail
2024-07-16 Deleted XREF UM-BBD_enzymeID:e0418
2020-06-22 Added XREF RHEA:17445
2003-11-08 Deleted XREF EC:1.18.99.1
2003-11-08 Added XREF EC:1.12.7.2
2003-10-27 Added XREF MetaCyc:HYDROG-RXN
2003-10-27 Added XREF UM-BBD_enzymeID:e0418
2001-03-30 Added XREF EC:1.18.99.1
Timestamp Action Category Detail
2008-03-10 Added SECONDARY GO:0016951 (nickel-iron-selenium hydrogenase activity)
2008-03-10 Added SECONDARY GO:0016950 (nickel-iron hydrogenase activity)
2008-03-10 Added SECONDARY GO:0016949 (nickel hydrogenase activity)
2008-03-10 Added SECONDARY GO:0016948 (iron hydrogenase activity)
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