GO:0008901
JSON
ferredoxin hydrogenase activity
Molecular Function
Definition (GO:0008901 GONUTS page)
Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
Secondary IDs
GO:0016948, GO:0016949, GO:0016950, GO:0016951
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
hydrogen:ferredoxin oxidoreductase activity | exact |
Ni-Fe hydrogenase activity | narrow |
hydrogenase II | related |
Ni-Fe-Se hydrogenase activity | narrow |
nickel-iron hydrogenase activity | narrow |
nickel-iron-selenium hydrogenase activity | narrow |
H(2) oxidizing hydrogenase activity | broad |
H(2) producing hydrogenase activity | broad |
bidirectional hydrogenase activity | broad |
hydrogen-lyase activity | broad |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0008901
Child Term | Relationship to GO:0008901 |
---|---|
ferredoxin hydrogenase complex
|
capable_of |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.12.7.2 | |
InterPro | IPR001821 | [NiFe]-hydrogenase, small subunit |
InterPro | IPR002844 | F420-dependent methylenetetrahydromethanopterin dehydrogenase |
InterPro | IPR008953 | Iron hydrogenase, small subunit HydB-type |
InterPro | IPR013352 | Iron hydrogenase, subset |
InterPro | IPR018194 | Nickel-dependent hydrogenase, large subunit, nickel binding site |
InterPro | IPR036080 | F420-dependent methylenetetrahydromethanopterin dehydrogenase superfamily |
MetaCyc | HYDROG-RXN | |
RHEA | 17445 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:33738 | di-mu-sulfido-diiron(1+) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:33737 | di-mu-sulfido-diiron(2+) |
has_participant | CHEBI | CHEBI:18276 | dihydrogen |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0008901 based on ALL annotations
The top 100 of 144 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ferredoxin hydrogenase activity
|
4,965.33 | 100.00 | 39,260 | 39,260 |
ferredoxin hydrogenase complex
|
4,965.33 | 27.82 | 10,923 | 10,923 |
[Ni-Fe] hydrogenase complex
|
4,960.79 | 27.81 | 10,922 | 10,932 |
hydrogenase (acceptor) activity
|
4,488.11 | 11.06 | 4,392 | 4,859 |
nickel cation binding
|
482.51 | 8.78 | 18,706 | 192,498 |
3 iron, 4 sulfur cluster binding
|
444.78 | 7.14 | 10,200 | 113,869 |
anaerobic respiration
|
371.40 | 6.26 | 10,921 | 146,007 |
cell envelope
|
113.03 | 2.20 | 15,778 | 693,121 |
methylenetetrahydromethanopterin dehydrogenase activity
|
4,829.56 | 1.90 | 747 | 768 |
iron-sulfur cluster binding
|
59.59 | 1.19 | 19,704 | 1,641,943 |
Totals | 286754 | 158991161 |
No co-occurrence statistics for GO:0008901 based on MANUAL annotations
The top 11 of 11 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ferredoxin hydrogenase activity
|
215,299.84 | 100.00 | 6 | 6 |
ferredoxin hydrogenase complex
|
215,299.84 | 50.00 | 3 | 3 |
carbazole catabolic process
|
61,514.24 | 18.18 | 2 | 7 |
iron-sulfur cluster binding
|
583.47 | 0.27 | 1 | 369 |
cytosolic [4Fe-4S] assembly targeting complex
|
539.60 | 0.25 | 1 | 399 |
protein maturation by [4Fe-4S] cluster transfer
|
434.95 | 0.20 | 1 | 495 |
2 iron, 2 sulfur cluster binding
|
392.17 | 0.18 | 2 | 1,098 |
proton motive force-driven ATP synthesis
|
382.42 | 0.18 | 3 | 1,689 |
iron-sulfur cluster assembly
|
110.81 | 0.05 | 1 | 1,943 |
cytosol
|
2.56 | 0.00 | 1 | 84,217 |
Totals | 22 | 282502 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-16 | Deleted | XREF | UM-BBD_enzymeID:e0418 |
2020-10-08 | Added | SYNONYM | hydrogenase (ferredoxin) activity |
2020-10-08 | Deleted | SYNONYM | hydrogenase (ferredoxin) activity |
2020-06-22 | Added | XREF | RHEA:17445 |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. |
2008-04-01 | Updated | RELATION | is a GO:0016699 (oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor) |
2008-03-10 | Added | SECONDARY | GO:0016951 (nickel-iron-selenium hydrogenase activity) |
2008-03-10 | Added | SECONDARY | GO:0016950 (nickel-iron hydrogenase activity) |
2008-03-10 | Added | SECONDARY | GO:0016949 (nickel hydrogenase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-11-08 | Updated | TERM | ferredoxin hydrogenase activity |
2003-03-19 | Updated | TERM | hydrogenase activity |
2002-02-06 | Updated | TERM | hydrogenase |
2001-04-03 | Updated | TERM | hydrogenase |
2001-03-30 | Added | TERM | hydrogenase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | hydrogenase (ferredoxin) activity |
2020-10-08 | Deleted | SYNONYM | hydrogenase (ferredoxin) activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. |
2008-03-10 | Added | SYNONYM | nickel-iron-selenium hydrogenase activity |
2008-03-10 | Added | SYNONYM | nickel-iron hydrogenase activity |
2008-03-10 | Added | SYNONYM | nickel hydrogenase activity |
2008-03-10 | Added | SYNONYM | iron-only hydrogenase activity |
2008-03-10 | Added | SYNONYM | iron hydrogenase activity |
2008-03-10 | Added | SYNONYM | Ni-Fe-Se hydrogenase activity |
2008-03-10 | Added | SYNONYM | Ni-Fe hydrogenase activity |
2008-03-10 | Deleted | SYNONYM | 1.18.99.1 |
2007-11-08 | Added | SYNONYM | hydrogen:ferredoxin oxidoreductase activity |
2007-11-08 | Deleted | SYNONYM | [Fe] hydrogenase |
2007-11-08 | Deleted | SYNONYM | hydrogen:ferredoxin oxidoreductase |
2007-11-08 | Added | SYNONYM | [Fe] hydrogenase activity |
2007-09-06 | Added | SYNONYM | H(2) producing hydrogenase activity |
2007-09-06 | Added | SYNONYM | H(2) oxidizing hydrogenase activity |
2007-09-06 | Deleted | SYNONYM | bidirectional hydrogenase |
2007-09-06 | Deleted | SYNONYM | hydrogen-lyase |
2007-09-06 | Deleted | SYNONYM | hydrogenase (ferredoxin) |
2007-09-06 | Deleted | SYNONYM | hydrogenlyase |
2007-09-06 | Added | SYNONYM | uptake hydrogenase activity |
2007-09-06 | Added | SYNONYM | hydrogenlyase activity |
2007-09-06 | Added | SYNONYM | hydrogenase (ferredoxin) activity |
2007-09-06 | Deleted | SYNONYM | uptake hydrogenase |
2007-09-06 | Added | SYNONYM | bidirectional hydrogenase activity |
2007-09-06 | Added | SYNONYM | hydrogen-lyase activity |
2007-08-09 | Added | SYNONYM | [Fe] hydrogenase |
2007-08-09 | Added | SYNONYM | [Fe] hydrogenase gamma |
2007-08-09 | Added | SYNONYM | bidirectional hydrogenase |
2007-08-09 | Added | SYNONYM | hydrogen-lyase |
2007-08-09 | Added | SYNONYM | hydrogen:ferredoxin oxidoreductase |
2007-08-09 | Added | SYNONYM | hydrogenase (ferredoxin) |
2007-08-09 | Added | SYNONYM | hydrogenase I |
2007-08-09 | Added | SYNONYM | hydrogenase II |
2007-08-09 | Added | SYNONYM | hydrogenase activity |
2007-08-09 | Added | SYNONYM | hydrogenlyase |
2007-08-09 | Added | SYNONYM | uptake hydrogenase |
2007-08-09 | Deleted | SYNONYM | hydrogenase activity |
2007-08-09 | Deleted | SYNONYM | 1.18.99.1 |
2007-08-09 | Deleted | SYNONYM | H2 oxidizing hydrogenase |
2007-08-09 | Deleted | SYNONYM | H2 producing hydrogenase |
2007-08-09 | Deleted | SYNONYM | [Fe] hydrogenase |
2007-08-09 | Deleted | SYNONYM | [Fe] hydrogenase gamma |
2007-08-09 | Deleted | SYNONYM | bidirectional hydrogenase |
2007-08-09 | Deleted | SYNONYM | hydrogen-lyase |
2007-08-09 | Deleted | SYNONYM | hydrogen:ferredoxin oxidoreductase |
2007-08-09 | Deleted | SYNONYM | hydrogenase (ferredoxin) |
2007-08-09 | Deleted | SYNONYM | hydrogenase I |
2007-08-09 | Deleted | SYNONYM | hydrogenase II |
2007-08-09 | Deleted | SYNONYM | hydrogenlyase |
2007-08-09 | Deleted | SYNONYM | uptake hydrogenase |
2007-08-09 | Added | SYNONYM | 1.18.99.1 |
2007-08-09 | Added | SYNONYM | H2 oxidizing hydrogenase |
2007-08-09 | Added | SYNONYM | H2 producing hydrogenase |
2007-08-05 | Added | SYNONYM | H2 oxidizing hydrogenase |
2007-08-05 | Added | SYNONYM | hydrogenase I |
2007-08-05 | Added | SYNONYM | hydrogenase (ferredoxin) |
2007-08-05 | Added | SYNONYM | hydrogen:ferredoxin oxidoreductase |
2007-08-05 | Added | SYNONYM | hydrogen-lyase |
2007-08-05 | Added | SYNONYM | bidirectional hydrogenase |
2007-08-05 | Added | SYNONYM | uptake hydrogenase |
2007-08-05 | Added | SYNONYM | hydrogenlyase |
2007-08-05 | Added | SYNONYM | 1.18.99.1 |
2007-08-05 | Added | SYNONYM | hydrogenase II |
2007-08-05 | Added | SYNONYM | H2 producing hydrogenase |
2007-08-05 | Added | SYNONYM | [Fe] hydrogenase |
2007-08-05 | Added | SYNONYM | [Fe] hydrogenase gamma |
2004-04-19 | Added | SYNONYM | hydrogenase activity |
2004-04-16 | Deleted | SYNONYM | hydrogenase activity |
2003-11-08 | Added | SYNONYM | hydrogenase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016699 (oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-16 | Deleted | XREF | UM-BBD_enzymeID:e0418 |
2020-06-22 | Added | XREF | RHEA:17445 |
2003-11-08 | Deleted | XREF | EC:1.18.99.1 |
2003-11-08 | Added | XREF | EC:1.12.7.2 |
2003-10-27 | Added | XREF | MetaCyc:HYDROG-RXN |
2003-10-27 | Added | XREF | UM-BBD_enzymeID:e0418 |
2001-03-30 | Added | XREF | EC:1.18.99.1 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-03-10 | Added | SECONDARY | GO:0016951 (nickel-iron-selenium hydrogenase activity) |
2008-03-10 | Added | SECONDARY | GO:0016950 (nickel-iron hydrogenase activity) |
2008-03-10 | Added | SECONDARY | GO:0016949 (nickel hydrogenase activity) |
2008-03-10 | Added | SECONDARY | GO:0016948 (iron hydrogenase activity) |
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