This term is obsolete.

GO:0008995 JSON

ribonuclease E activity

Molecular Function

Definition (GO:0008995 GONUTS page)

Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group. PMID:10722715 PMID:16854990

12,283 annotations

Ancestor Chart

Ancestor chart for GO:0008995
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0B4KFF6 7227 A0A0B4KFF6_DROME GO:0004518 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25392983
NOT-qualified manual protein A0A8I6A3V5 10116 A0A8I6A3V5_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ACW3 10116 A0A8I6ACW3_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JWR1 10116 A6JWR1_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8DY77 7227 A8DY77_DROME GO:0004518 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25392983
NOT-qualified manual protein D3Z898 10116 D3Z898_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A2W9 10116 D4A2W9_RAT GO:0004540 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
InterPro IPR028878 Ribonuclease E
MetaCyc 3.1.26.12-RXN

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0008995 based on ALL annotations
The top 59 of 59 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ribonuclease E activity
15,871.91 100.00 12,282 12,282
cytoplasmic side of plasma membrane
937.30 5.89 11,664 197,514
mRNA catabolic process
841.85 5.29 11,664 219,909
RNA nuclease activity
756.41 4.77 12,279 257,653
RNA endonuclease activity
594.42 3.74 11,664 311,444
RNA processing
185.28 1.17 12,281 1,052,040
rRNA processing
176.12 1.11 12,281 1,106,747
tRNA binding
143.28 0.90 11,663 1,291,960
tRNA processing
110.41 0.70 12,161 1,748,269
rRNA binding
95.72 0.60 12,281 2,036,482
Totals 204937 213398853
No co-occurrence statistics for GO:0008995 based on MANUAL annotations
The top 29 of 29 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ribonuclease E activity
645,899.50 100.00 2 2
regulation of RNA helicase activity
645,899.50 50.00 1 1
bacterial degradosome
161,474.88 20.00 1 4
endoribonuclease complex
43,059.97 6.25 1 15
DEAD/H-box RNA helicase binding
10,764.99 1.64 1 60
rRNA 5'-end processing
5,338.01 0.82 1 121
molecular function inhibitor activity
4,968.46 0.76 1 130
protein serine/threonine phosphatase inhibitor activity
2,282.33 0.35 1 283
7S RNA binding
1,626.95 0.25 1 397
RNA nuclease activity
1,516.20 0.23 1 426
Totals 33 571578

Change Log

Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:3.1.26.12-RXN
2008-05-13 Added DEFINITION Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
2008-04-01 Updated RELATION is a GO:0004540 (RNA nuclease activity)
2006-09-29 Added DEFINITION Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
2003-03-19 Updated TERM ribonuclease E activity
2002-02-06 Updated TERM ribonuclease E
2001-04-03 Updated TERM ribonuclease E
2001-03-30 Added TERM ribonuclease E
Timestamp Action Category Detail
2003-03-19 Updated TERM ribonuclease E activity
2002-02-06 Updated TERM ribonuclease E
2001-04-03 Updated TERM ribonuclease E
2001-03-30 Added TERM ribonuclease E
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
2006-09-29 Added DEFINITION Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004540 (RNA nuclease activity)
Timestamp Action Category Detail
2009-05-21 Added XREF MetaCyc:3.1.26.12-RXN
Timestamp Action Category Detail
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.