This term is obsolete.

GO:0009042 JSON

valine-pyruvate transaminase activity

Molecular Function

Definition (GO:0009042 GONUTS page)

Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.

3,970 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
L-valine:pyruvate aminotransferase activity related
transaminase C activity narrow
valine--pyruvate aminotransferase activity related
valine-pyruvate aminotransferase activity exact
alanine--valine transaminase activity related
alanine-oxoisovalerate aminotransferase activity related

Ancestor Chart

Ancestor chart for GO:0009042
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I940 7227 Q8I940_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.6.1.66
KEGG_REACTION R01215
MetaCyc VALINE-PYRUVATE-AMINOTRANSFER-RXN
RHEA 22912

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57762 L-valine zwitterion
has_participant CHEBI CHEBI:57972 L-alanine zwitterion
has_participant CHEBI CHEBI:15361 pyruvate
has_participant CHEBI CHEBI:11851 3-methyl-2-oxobutanoate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0009042 based on ALL annotations
The top 33 of 33 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0009042
valine-pyruvate transaminase activity
49,963.40 100.00 3,966 3,966
GO:1901605
alpha-amino acid metabolic process
1,292.74 2.58 3,667 141,727
GO:0004021
L-alanine:2-oxoglutarate aminotransferase activity
1,488.75 1.90 198 6,645
GO:0008483
transaminase activity
164.92 0.33 3,966 1,201,488
GO:0004069
L-aspartate:2-oxoglutarate aminotransferase activity
126.72 0.24 139 54,806
GO:0009058
biosynthetic process
114.75 0.23 3,863 1,682,002
GO:0030170
pyridoxal phosphate binding
109.62 0.22 3,863 1,760,728
GO:0047536
2-aminoadipate transaminase activity
133.16 0.17 18 6,754
GO:0009074
aromatic amino acid family catabolic process
38.28 0.04 4 5,221
GO:0008793
aromatic-amino-acid transaminase activity
27.56 0.04 4 7,251
Totals 23513 126508626
No co-occurrence statistics for GO:0009042 based on MANUAL annotations
The top 7 of 7 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0009042
valine-pyruvate transaminase activity
235,255.50 100.00 6 6
GO:0042852
L-alanine biosynthetic process
235,255.52 16.67 1 1
GO:1901605
alpha-amino acid metabolic process
11,762.77 5.00 6 120
GO:0030632
D-alanine biosynthetic process
5,114.25 1.96 1 46
GO:0009099
L-valine biosynthetic process
383.15 0.16 1 614
GO:0008483
transaminase activity
221.73 0.09 1 1,061
GO:0005829
cytosol
15.76 0.01 6 89,580
Totals 22 91428

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM valine--pyruvate aminotransferase activity
2020-10-08 Added SYNONYM alanine-oxoisovalerate aminotransferase activity
2020-10-08 Deleted SYNONYM valine--pyruvate aminotransferase activity
2020-10-08 Deleted SYNONYM alanine--valine transaminase activity
2020-10-08 Added SYNONYM L-valine:pyruvate aminotransferase activity
2020-10-08 Added SYNONYM alanine--valine transaminase activity
2020-10-08 Deleted SYNONYM alanine-oxoisovalerate aminotransferase activity
2020-10-08 Deleted SYNONYM L-valine:pyruvate aminotransferase activity
2019-06-20 Added XREF KEGG_REACTION:R01215
2019-06-20 Deleted XREF KEGG:R01215
Timestamp Action Category Detail
2003-09-09 Updated TERM valine-pyruvate transaminase activity
2003-03-19 Updated TERM valine-pyruvate aminotransferase activity
2002-02-06 Updated TERM valine-pyruvate aminotransferase
2001-11-07 Updated TERM valine-pyruvate aminotransferase
2001-04-03 Updated TERM valine--pyruvate aminotransferase
2001-03-30 Added TERM valine--pyruvate aminotransferase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM valine--pyruvate aminotransferase activity
2020-10-08 Added SYNONYM alanine-oxoisovalerate aminotransferase activity
2020-10-08 Deleted SYNONYM valine--pyruvate aminotransferase activity
2020-10-08 Deleted SYNONYM alanine--valine transaminase activity
2020-10-08 Added SYNONYM L-valine:pyruvate aminotransferase activity
2020-10-08 Added SYNONYM alanine--valine transaminase activity
2020-10-08 Deleted SYNONYM alanine-oxoisovalerate aminotransferase activity
2020-10-08 Deleted SYNONYM L-valine:pyruvate aminotransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
2007-11-08 Added SYNONYM alanine-oxoisovalerate aminotransferase activity
2007-11-08 Added SYNONYM L-valine:pyruvate aminotransferase activity
2007-09-06 Added SYNONYM transaminase C activity
2007-09-06 Added SYNONYM alanine--valine transaminase activity
2007-09-06 Added SYNONYM valine--pyruvate aminotransferase activity
2007-08-09 Deleted SYNONYM valine-pyruvate aminotransferase activity
2007-08-09 Added SYNONYM valine-pyruvate aminotransferase activity
2004-04-19 Added SYNONYM valine-pyruvate aminotransferase activity
2004-04-16 Deleted SYNONYM valine-pyruvate aminotransferase activity
2003-10-27 Added SYNONYM valine-pyruvate aminotransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008483 (transaminase activity)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R01215
2019-06-20 Deleted XREF KEGG:R01215
2018-07-13 Added XREF RHEA:22912
2018-07-13 Deleted XREF RHEA:22915
2010-10-11 Added XREF KEGG:R01215
2010-10-11 Added XREF RHEA:22915
2003-10-27 Added XREF MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN
2001-03-30 Added XREF EC:2.6.1.66
Timestamp Action Category Detail
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