GO:0009376
JSON
HslUV protease complex
Cellular Component
Definition (GO:0009376 GONUTS page)
A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. PMID:12670962
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ClpYQ protease complex | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0009376 | HslUV protease complex | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A022PQZ0 | 4155 | A0A022PQZ0_ERYGU | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A022PY49 | 4155 | A0A022PY49_ERYGU | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A022QF08 | 4155 | A0A022QF08_ERYGU | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059B690 | 71139 | A0A059B690_EUCGR | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059B6X6 | 71139 | A0A059B6X6_EUCGR | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059B9U1 | 71139 | A0A059B9U1_EUCGR | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A061E742 | 3641 | A0A061E742_THECC | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A061ERE5 | 3641 | A0A061ERE5_THECC | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A067EGP5 | 2711 | A0A067EGP5_CITSI | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A078G8S0 | 3708 | A0A078G8S0_BRANA | GO:0005829 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004491 | Heat shock protein HslU |
InterPro | IPR022281 | ATP-dependent protease, HslV subunit |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0009376 based on ALL annotations
The top 100 of 151 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
HslUV protease complex
|
2,355.04 | 100.00 | 82,775 | 82,775 |
proteolysis involved in protein catabolic process
|
810.91 | 34.43 | 82,763 | 240,359 |
proteasome-activating activity
|
2,196.37 | 20.22 | 16,984 | 18,211 |
positive regulation of proteasomal protein catabolic process
|
2,053.39 | 19.92 | 16,984 | 19,479 |
threonine-type endopeptidase activity
|
852.58 | 17.06 | 20,195 | 55,784 |
protein unfolding
|
532.76 | 12.06 | 16,985 | 75,082 |
proteasome core complex
|
416.97 | 11.43 | 20,195 | 114,061 |
ATP-dependent protein folding chaperone
|
214.38 | 8.20 | 37,571 | 412,733 |
protein catabolic process
|
178.87 | 6.00 | 18,350 | 241,599 |
peptidase activity
|
136.17 | 5.76 | 78,275 | 1,353,802 |
Totals | 887207 | 138457762 |
No co-occurrence statistics for GO:0009376 based on MANUAL annotations
The top 48 of 48 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
HslUV protease complex
|
16,561.53 | 100.00 | 78 | 78 |
rolling circle DNA replication
|
12,421.15 | 3.80 | 3 | 4 |
protein denaturation
|
12,421.15 | 3.80 | 3 | 4 |
cell division
|
483.66 | 2.81 | 33 | 1,130 |
proteolysis involved in protein catabolic process
|
349.73 | 2.11 | 76 | 3,599 |
negative regulation of protein polymerization
|
2,365.93 | 1.19 | 1 | 7 |
ATP binding
|
188.29 | 1.14 | 74 | 6,509 |
positive regulation of proteolysis involved in protein catabolic process
|
720.07 | 1.00 | 1 | 23 |
mitochondrial DNA replication
|
182.66 | 0.97 | 6 | 544 |
mitochondrial nucleoid
|
173.72 | 0.93 | 6 | 572 |
Totals | 428 | 514763 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2021-06-18 | Deleted | RELATION | is a GO:1904949 (ATPase complex) |
2016-08-31 | Added | RELATION | is a GO:1904949 (ATPase complex) |
2016-08-31 | Added | RELATION | capable of GO:0004176 (ATP-dependent peptidase activity) |
2014-05-16 | Deleted | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex. |
2014-05-16 | Added | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. |
2013-09-27 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2013-09-25 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-09-25 | Added | RELATION | is a GO:0031597 (cytosolic proteasome complex) |
2008-05-13 | Added | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-05-24 | Updated | TERM | HslUV protease complex |
2002-02-06 | Updated | TERM | HslUV protease |
2001-04-03 | Updated | TERM | HslUV protease |
2001-03-30 | Added | TERM | HslUV protease |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-05-16 | Deleted | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex. |
2014-05-16 | Added | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. |
2008-05-13 | Added | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex. |
2008-05-12 | Deleted | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex. |
2007-08-09 | Added | SYNONYM | ClpYQ protease complex |
2007-08-09 | Deleted | SYNONYM | ClpYQ protease complex |
2007-05-27 | Added | DEFINITION | A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex. |
2007-05-18 | Added | SYNONYM | ClpYQ protease complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-06-18 | Deleted | RELATION | is a GO:1904949 (ATPase complex) |
2016-08-31 | Added | RELATION | is a GO:1904949 (ATPase complex) |
2016-08-31 | Added | RELATION | capable of GO:0004176 (ATP-dependent peptidase activity) |
2013-09-27 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2013-09-25 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-09-25 | Added | RELATION | is a GO:0031597 (cytosolic proteasome complex) |
2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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