This term is obsolete.

GO:0009376 JSON

HslUV protease complex

Cellular Component

Definition (GO:0009376 GONUTS page)

A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. PMID:12670962

83,712 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ClpYQ protease complex exact

Ancestor Chart

Ancestor chart for GO:0009376
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0009376 HslUV protease complex Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A022PQZ0 4155 A0A022PQZ0_ERYGU GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022PY49 4155 A0A022PY49_ERYGU GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022QF08 4155 A0A022QF08_ERYGU GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B690 71139 A0A059B690_EUCGR GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B6X6 71139 A0A059B6X6_EUCGR GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B9U1 71139 A0A059B9U1_EUCGR GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A061E742 3641 A0A061E742_THECC GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A061ERE5 3641 A0A061ERE5_THECC GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A067EGP5 2711 A0A067EGP5_CITSI GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A078G8S0 3708 A0A078G8S0_BRANA GO:0005829 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR004491 Heat shock protein HslU
InterPro IPR022281 ATP-dependent protease, HslV subunit

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0009376 based on ALL annotations
The top 100 of 150 co-occurring terms
Co-occurring Term PR S% #Together #Compared
HslUV protease complex
2,368.57 100.00 83,660 83,660
proteolysis involved in protein catabolic process
826.13 34.88 83,647 239,821
proteasome-activating activity
2,199.30 20.18 17,150 18,470
positive regulation of proteasomal protein catabolic process
2,057.49 19.88 17,150 19,743
threonine-type endopeptidase activity
846.86 16.95 20,397 57,048
protein unfolding
534.22 12.03 17,151 76,043
proteasome core complex
410.67 11.28 20,397 117,640
ATP-dependent protein folding chaperone
213.17 8.12 38,029 422,542
protein catabolic process
181.78 6.04 18,516 241,268
peptidase activity
132.67 5.58 79,132 1,412,747
Totals 898087 141824788
No co-occurrence statistics for GO:0009376 based on MANUAL annotations
The top 48 of 48 co-occurring terms
Co-occurring Term PR S% #Together #Compared
HslUV protease complex
18,096.58 100.00 78 78
rolling circle DNA replication
13,572.43 3.80 3 4
protein denaturation
13,572.43 3.80 3 4
cell division
488.70 2.60 33 1,222
proteolysis involved in protein catabolic process
345.82 1.91 76 3,977
mitochondrial DNA replication
346.90 1.56 6 313
negative regulation of protein polymerization
2,585.23 1.19 1 7
ATP binding
195.52 1.08 74 6,849
positive regulation of proteolysis involved in protein catabolic process
786.81 1.00 1 23
mitochondrial nucleoid
176.84 0.87 6 614
Totals 428 553088

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2021-06-18 Deleted RELATION is a GO:1904949 (ATPase complex)
2016-08-31 Added RELATION is a GO:1904949 (ATPase complex)
2016-08-31 Added RELATION capable of GO:0004176 (ATP-dependent peptidase activity)
2014-05-16 Deleted DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex.
2014-05-16 Added DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.
2013-09-27 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2013-09-25 Deleted RELATION is a GO:0043234 (protein complex)
2013-09-25 Added RELATION is a GO:0031597 (cytosolic proteasome complex)
2008-05-13 Added DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex.
Timestamp Action Category Detail
2002-05-24 Updated TERM HslUV protease complex
2002-02-06 Updated TERM HslUV protease
2001-04-03 Updated TERM HslUV protease
2001-03-30 Added TERM HslUV protease
Timestamp Action Category Detail
2014-05-16 Deleted DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex.
2014-05-16 Added DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.
2008-05-13 Added DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex.
2008-05-12 Deleted DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex.
2007-08-09 Added SYNONYM ClpYQ protease complex
2007-08-09 Deleted SYNONYM ClpYQ protease complex
2007-05-27 Added DEFINITION A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex.
2007-05-18 Added SYNONYM ClpYQ protease complex
Timestamp Action Category Detail
2021-06-18 Deleted RELATION is a GO:1904949 (ATPase complex)
2016-08-31 Added RELATION is a GO:1904949 (ATPase complex)
2016-08-31 Added RELATION capable of GO:0004176 (ATP-dependent peptidase activity)
2013-09-27 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2013-09-25 Deleted RELATION is a GO:0043234 (protein complex)
2013-09-25 Added RELATION is a GO:0031597 (cytosolic proteasome complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044444 (obsolete cytoplasmic part)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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