This term is obsolete.
The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.

GO:0009451 JSON

RNA modification

Biological Process

Definition (GO:0009451 GONUTS page)

The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.

Comments

The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.

Secondary IDs

GO:0016547

5,070,382 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
RNA editing narrow

Ancestor Chart

Ancestor chart for GO:0009451
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0009451

Child Term Relationship to
GO:0009451
rRNA modification
is_a
tRNA modification
is_a
mRNA modification
is_a
base conversion or substitution editing
is_a
oxidative RNA demethylation
is_a
mitochondrial RNA modification
is_a
RNA nucleotide insertion
is_a
chloroplast RNA modification
is_a
RNA nucleotide deletion
is_a
pseudouridine synthesis
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein Q9SB36 3702 PP337_ARATH GO:0009451 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21288264

Cross-references

Database ID Description
InterPro IPR000748 Pseudouridine synthase, RsuA/RluB/E/F
InterPro IPR001406 Pseudouridine synthase I, TruA
InterPro IPR001656 Pseudouridine synthase, TruD
InterPro IPR006145 Pseudouridine synthase, RsuA/RluA-like
InterPro IPR006224 Pseudouridine synthase, RluA-like, conserved site
InterPro IPR006225 Pseudouridine synthase, RluC/RluD
InterPro IPR011760 Pseudouridine synthase, TruD, insertion domain
InterPro IPR014780 tRNA pseudouridine synthase II, TruB
InterPro IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal
InterPro IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0009451 based on ALL annotations
The top 100 of 1,064 co-occurring terms
Co-occurring Term PR S% #Together #Compared
RNA modification
1,414.11 100.00 137,853 137,853
rRNA (uridine-C5-)-methyltransferase activity
703.36 14.05 22,565 45,367
RNA methyltransferase activity
128.61 6.88 30,337 333,562
rRNA base methylation
137.54 6.50 22,555 231,889
tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
1,024.54 4.26 5,970 8,240
S-adenosylmethionine-dependent methyltransferase activity
70.94 4.26 30,331 604,634
RNA processing
40.77 2.62 30,335 1,052,040
RNA binding
27.16 1.91 111,348 5,796,616
rRNA methylation
29.70 1.50 6,910 329,008
rRNA (uridine) methyltransferase activity
821.52 1.47 2,049 3,527
Totals 578582 87653365
No co-occurrence statistics for GO:0009451 based on MANUAL annotations
The top 100 of 125 co-occurring terms
Co-occurring Term PR S% #Together #Compared
RNA modification
285.61 100.00 4,523 4,523
intracellular membrane-bounded organelle
57.04 16.72 2,290 11,467
RNA binding
25.80 8.39 2,455 27,182
chloroplast RNA processing
178.86 1.36 62 99
chloroplast
2.32 0.54 72 8,862
mitochondrial mRNA editing complex
61.94 0.39 18 83
mitochondrion
1.07 0.34 171 45,791
kinetoplast
5.60 0.12 6 306
mRNA editing complex
63.47 0.09 4 18
mRNA modification
2.17 0.08 4 526
Totals 9730 188239

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_yeast 163

Change Log

Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:11.06
2019-05-04 Added XREF MIPS_funcat:11.06
2013-04-18 Updated SUBSET goslim_yeast
2011-08-14 Added SUBSET goslim_yeast
2010-04-16 Deleted SYNONYM RNA editing
2010-04-16 Added SYNONYM RNA editing
2009-03-15 Added XREF Wikipedia:RNA_editing
2008-05-13 Added DEFINITION The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
2008-05-12 Deleted DEFINITION The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
2008-04-01 Updated RELATION is a GO:0043412 (macromolecule modification)
Timestamp Action Category Detail
2002-02-06 Updated TERM RNA modification
2001-04-03 Updated TERM RNA modification
2001-03-30 Added TERM RNA modification
Timestamp Action Category Detail
2010-04-16 Deleted SYNONYM RNA editing
2010-04-16 Added SYNONYM RNA editing
2008-05-13 Added DEFINITION The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
2008-05-12 Deleted DEFINITION The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
2007-08-09 Deleted SYNONYM RNA editing
2007-08-09 Added SYNONYM RNA editing
2007-07-29 Added SYNONYM RNA editing
2007-07-27 Updated DEFINITION The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
2006-03-15 Updated DEFINITION The covalent alteration of one or more nucleotides within RNA, resulting in a change in the properties of the RNA.
2005-07-08 Updated DEFINITION The covalent or conformational alteration of one or more nucleotides within RNA, resulting in a change in the properties of the RNA.
2001-08-06 Added DEFINITION The enzymatic modification of the chemical structure of specific sites in RNA.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0043412 (macromolecule modification)
2008-04-01 Updated RELATION is a GO:0016070 (RNA metabolic process)
Timestamp Action Category Detail
2020-02-28 Deleted XREF MIPS_funcat:11.06
2019-05-04 Added XREF MIPS_funcat:11.06
2009-03-15 Added XREF Wikipedia:RNA_editing
Timestamp Action Category Detail
2013-04-18 Updated SUBSET goslim_yeast
2011-08-14 Added SUBSET goslim_yeast
2007-07-29 Added SECONDARY GO:0016547 (RNA editing)
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