The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.
GO:0009451
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RNA modification
Biological Process
Definition (GO:0009451 GONUTS page)
The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
Comments
The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.
Secondary IDs
GO:0016547
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
RNA editing | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0009451
Child Term | Relationship to GO:0009451 |
---|---|
rRNA modification
|
is_a |
tRNA modification
|
is_a |
mRNA modification
|
is_a |
base conversion or substitution editing
|
is_a |
oxidative RNA demethylation
|
is_a |
mitochondrial RNA modification
|
is_a |
RNA nucleotide insertion
|
is_a |
chloroplast RNA modification
|
is_a |
RNA nucleotide deletion
|
is_a |
pseudouridine synthesis
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | Q9SB36 | 3702 | PP337_ARATH | GO:0009451 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21288264 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000748 | Pseudouridine synthase, RsuA/RluB/E/F |
InterPro | IPR001406 | Pseudouridine synthase I, TruA |
InterPro | IPR001656 | Pseudouridine synthase, TruD |
InterPro | IPR006145 | Pseudouridine synthase, RsuA/RluA-like |
InterPro | IPR006224 | Pseudouridine synthase, RluA-like, conserved site |
InterPro | IPR006225 | Pseudouridine synthase, RluC/RluD |
InterPro | IPR011760 | Pseudouridine synthase, TruD, insertion domain |
InterPro | IPR014780 | tRNA pseudouridine synthase II, TruB |
InterPro | IPR015225 | tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal |
InterPro | IPR015240 | tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0009451 based on ALL annotations
The top 100 of 1,064 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
RNA modification
|
1,414.11 | 100.00 | 137,853 | 137,853 |
rRNA (uridine-C5-)-methyltransferase activity
|
703.36 | 14.05 | 22,565 | 45,367 |
RNA methyltransferase activity
|
128.61 | 6.88 | 30,337 | 333,562 |
rRNA base methylation
|
137.54 | 6.50 | 22,555 | 231,889 |
tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
|
1,024.54 | 4.26 | 5,970 | 8,240 |
S-adenosylmethionine-dependent methyltransferase activity
|
70.94 | 4.26 | 30,331 | 604,634 |
RNA processing
|
40.77 | 2.62 | 30,335 | 1,052,040 |
RNA binding
|
27.16 | 1.91 | 111,348 | 5,796,616 |
rRNA methylation
|
29.70 | 1.50 | 6,910 | 329,008 |
rRNA (uridine) methyltransferase activity
|
821.52 | 1.47 | 2,049 | 3,527 |
Totals | 578582 | 87653365 |
No co-occurrence statistics for GO:0009451 based on MANUAL annotations
The top 100 of 125 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
RNA modification
|
285.61 | 100.00 | 4,523 | 4,523 |
intracellular membrane-bounded organelle
|
57.04 | 16.72 | 2,290 | 11,467 |
RNA binding
|
25.80 | 8.39 | 2,455 | 27,182 |
chloroplast RNA processing
|
178.86 | 1.36 | 62 | 99 |
chloroplast
|
2.32 | 0.54 | 72 | 8,862 |
mitochondrial mRNA editing complex
|
61.94 | 0.39 | 18 | 83 |
mitochondrion
|
1.07 | 0.34 | 171 | 45,791 |
kinetoplast
|
5.60 | 0.12 | 6 | 306 |
mRNA editing complex
|
63.47 | 0.09 | 4 | 18 |
mRNA modification
|
2.17 | 0.08 | 4 | 526 |
Totals | 9730 | 188239 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_yeast | 163 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:11.06 |
2019-05-04 | Added | XREF | MIPS_funcat:11.06 |
2013-04-18 | Updated | SUBSET | goslim_yeast |
2011-08-14 | Added | SUBSET | goslim_yeast |
2010-04-16 | Deleted | SYNONYM | RNA editing |
2010-04-16 | Added | SYNONYM | RNA editing |
2009-03-15 | Added | XREF | Wikipedia:RNA_editing |
2008-05-13 | Added | DEFINITION | The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. |
2008-05-12 | Deleted | DEFINITION | The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. |
2008-04-01 | Updated | RELATION | is a GO:0043412 (macromolecule modification) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | RNA modification |
2001-04-03 | Updated | TERM | RNA modification |
2001-03-30 | Added | TERM | RNA modification |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-04-16 | Deleted | SYNONYM | RNA editing |
2010-04-16 | Added | SYNONYM | RNA editing |
2008-05-13 | Added | DEFINITION | The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. |
2008-05-12 | Deleted | DEFINITION | The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. |
2007-08-09 | Deleted | SYNONYM | RNA editing |
2007-08-09 | Added | SYNONYM | RNA editing |
2007-07-29 | Added | SYNONYM | RNA editing |
2007-07-27 | Updated | DEFINITION | The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. |
2006-03-15 | Updated | DEFINITION | The covalent alteration of one or more nucleotides within RNA, resulting in a change in the properties of the RNA. |
2005-07-08 | Updated | DEFINITION | The covalent or conformational alteration of one or more nucleotides within RNA, resulting in a change in the properties of the RNA. |
2001-08-06 | Added | DEFINITION | The enzymatic modification of the chemical structure of specific sites in RNA. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0043412 (macromolecule modification) |
2008-04-01 | Updated | RELATION | is a GO:0016070 (RNA metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:11.06 |
2019-05-04 | Added | XREF | MIPS_funcat:11.06 |
2009-03-15 | Added | XREF | Wikipedia:RNA_editing |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-04-18 | Updated | SUBSET | goslim_yeast |
2011-08-14 | Added | SUBSET | goslim_yeast |
2007-07-29 | Added | SECONDARY | GO:0016547 (RNA editing) |
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