This term is obsolete.

GO:0009931 JSON

calcium-dependent protein serine/threonine kinase activity

Molecular Function

Definition (GO:0009931 GONUTS page)

Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.

18,259 annotations

Ancestor Chart

Ancestor chart for GO:0009931
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0009931

Child Term Relationship to
GO:0009931
calcium,diacylglycerol-dependent serine/threonine kinase activity
is_a
calcium-dependent protein kinase regulator activity
regulates
calcium-dependent protein kinase inhibitor activity
negatively_regulates

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A0B4K7S5 7227 A0A0B4K7S5_DROME GO:0004672 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514
NOT-qualified manual protein A0A0G2QC55 10116 A0A0G2QC55_RAT GO:0004672 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A126GUQ5 7227 A0A126GUQ5_DROME GO:0004672 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514
NOT-qualified manual protein A0A1L8END5 8355 A0A1L8END5_XENLA GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1L8EV37 8355 A0A1L8EV37_XENLA GO:0016773 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1L8GLD7 8355 A0A1L8GLD7_XENLA GO:0004674 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A287AG10 9823 A0A287AG10_PIG GO:0004674 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2I2UNM6 9685 A0A2I2UNM6_FELCA GO:0004674 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5VFW3 9541 A0A2K5VFW3_MACFA GO:0004674 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18508765

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0009931 based on ALL annotations
The top 100 of 273 co-occurring terms
Co-occurring Term PR S% #Together #Compared
calcium-dependent protein serine/threonine kinase activity
84,792.86 100.00 2,299 2,299
calcium/calmodulin-dependent protein kinase activity
8,470.61 9.92 2,148 21,502
mitogen-activated protein kinase binding
2,358.09 1.50 72 2,589
calmodulin binding
821.15 0.97 2,142 221,184
macropinocytosis
2,627.38 0.74 22 710
protein phosphorylation
1,537.28 0.57 19 1,048
positive regulation of response to salt stress
2,154.45 0.49 14 551
cellular response to vascular endothelial growth factor stimulus
746.09 0.44 20 2,273
stress-induced premature senescence
3,643.44 0.43 11 256
intracellular signal transduction
325.88 0.38 2,146 558,389
Totals 18324 12071641
No co-occurrence statistics for GO:0009931 based on MANUAL annotations
The top 100 of 190 co-occurring terms
Co-occurring Term PR S% #Together #Compared
calcium-dependent protein serine/threonine kinase activity
602.24 100.00 2,145 2,145
calcium/calmodulin-dependent protein kinase activity
500.19 82.96 2,142 2,579
calmodulin binding
329.16 54.61 2,142 3,919
intracellular signal transduction
112.67 18.67 2,122 11,342
mitogen-activated protein kinase binding
211.52 3.16 72 205
toll-like receptor signaling pathway
69.49 1.49 36 312
response to cytokine
42.93 1.38 36 505
cytoplasm
7.20 1.20 2,144 179,389
nucleus
6.71 1.11 2,142 192,276
cellular response to vascular endothelial growth factor stimulus
95.59 0.89 20 126
Totals 13631 608974

Change Log

Timestamp Action Category Detail
2024-07-09 Deleted RELATION is a GO:0010857 (obsolete calcium-dependent protein kinase activity)
2020-11-03 Deleted DEFINITION Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.
2020-11-03 Added DEFINITION Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
2010-09-24 Added DEFINITION Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.
2009-01-15 Added RELATION is a GO:0010857 (obsolete calcium-dependent protein kinase activity)
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
2008-04-01 Updated RELATION is a GO:0004674 (protein serine/threonine kinase activity)
2007-05-27 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
Timestamp Action Category Detail
2004-02-26 Updated TERM calcium-dependent protein serine/threonine kinase activity
2003-03-19 Updated TERM calcium dependent protein serine/threonine kinase activity
2002-08-20 Added TERM calcium dependent protein serine/threonine kinase
Timestamp Action Category Detail
2020-11-03 Deleted DEFINITION Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.
2020-11-03 Added DEFINITION Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
2010-09-24 Added DEFINITION Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
2007-05-27 Added DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions.
Timestamp Action Category Detail
2024-07-09 Deleted RELATION is a GO:0010857 (obsolete calcium-dependent protein kinase activity)
2009-01-15 Added RELATION is a GO:0010857 (obsolete calcium-dependent protein kinase activity)
2008-04-01 Updated RELATION is a GO:0004674 (protein serine/threonine kinase activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
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