GO:0009931
JSON
calcium-dependent protein serine/threonine kinase activity
Molecular Function
Definition (GO:0009931 GONUTS page)
Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0009931
Child Term | Relationship to GO:0009931 |
---|---|
calcium,diacylglycerol-dependent serine/threonine kinase activity
|
is_a |
calcium-dependent protein kinase regulator activity
|
regulates |
calcium-dependent protein kinase inhibitor activity
|
negatively_regulates |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A0B4K7S5 | 7227 | A0A0B4K7S5_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514 | |
NOT-qualified manual | protein | A0A0G2QC55 | 10116 | A0A0G2QC55_RAT | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A126GUQ5 | 7227 | A0A126GUQ5_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514 | |
NOT-qualified manual | protein | A0A1L8END5 | 8355 | A0A1L8END5_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8EV37 | 8355 | A0A1L8EV37_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8GLD7 | 8355 | A0A1L8GLD7_XENLA | GO:0004674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A287AG10 | 9823 | A0A287AG10_PIG | GO:0004674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2I2UNM6 | 9685 | A0A2I2UNM6_FELCA | GO:0004674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5VFW3 | 9541 | A0A2K5VFW3_MACFA | GO:0004674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18508765 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0009931 based on ALL annotations
The top 100 of 273 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
calcium-dependent protein serine/threonine kinase activity
|
84,792.86 | 100.00 | 2,299 | 2,299 |
calcium/calmodulin-dependent protein kinase activity
|
8,470.61 | 9.92 | 2,148 | 21,502 |
mitogen-activated protein kinase binding
|
2,358.09 | 1.50 | 72 | 2,589 |
calmodulin binding
|
821.15 | 0.97 | 2,142 | 221,184 |
macropinocytosis
|
2,627.38 | 0.74 | 22 | 710 |
protein phosphorylation
|
1,537.28 | 0.57 | 19 | 1,048 |
positive regulation of response to salt stress
|
2,154.45 | 0.49 | 14 | 551 |
cellular response to vascular endothelial growth factor stimulus
|
746.09 | 0.44 | 20 | 2,273 |
stress-induced premature senescence
|
3,643.44 | 0.43 | 11 | 256 |
intracellular signal transduction
|
325.88 | 0.38 | 2,146 | 558,389 |
Totals | 18324 | 12071641 |
No co-occurrence statistics for GO:0009931 based on MANUAL annotations
The top 100 of 190 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
calcium-dependent protein serine/threonine kinase activity
|
602.24 | 100.00 | 2,145 | 2,145 |
calcium/calmodulin-dependent protein kinase activity
|
500.19 | 82.96 | 2,142 | 2,579 |
calmodulin binding
|
329.16 | 54.61 | 2,142 | 3,919 |
intracellular signal transduction
|
112.67 | 18.67 | 2,122 | 11,342 |
mitogen-activated protein kinase binding
|
211.52 | 3.16 | 72 | 205 |
toll-like receptor signaling pathway
|
69.49 | 1.49 | 36 | 312 |
response to cytokine
|
42.93 | 1.38 | 36 | 505 |
cytoplasm
|
7.20 | 1.20 | 2,144 | 179,389 |
nucleus
|
6.71 | 1.11 | 2,142 | 192,276 |
cellular response to vascular endothelial growth factor stimulus
|
95.59 | 0.89 | 20 | 126 |
Totals | 13631 | 608974 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-09 | Deleted | RELATION | is a GO:0010857 (obsolete calcium-dependent protein kinase activity) |
2020-11-03 | Deleted | DEFINITION | Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions. |
2020-11-03 | Added | DEFINITION | Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. |
2010-09-24 | Deleted | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
2010-09-24 | Added | DEFINITION | Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions. |
2009-01-15 | Added | RELATION | is a GO:0010857 (obsolete calcium-dependent protein kinase activity) |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
2008-04-01 | Updated | RELATION | is a GO:0004674 (protein serine/threonine kinase activity) |
2007-05-27 | Added | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-02-26 | Updated | TERM | calcium-dependent protein serine/threonine kinase activity |
2003-03-19 | Updated | TERM | calcium dependent protein serine/threonine kinase activity |
2002-08-20 | Added | TERM | calcium dependent protein serine/threonine kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | DEFINITION | Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions. |
2020-11-03 | Added | DEFINITION | Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. |
2010-09-24 | Deleted | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
2010-09-24 | Added | DEFINITION | Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
2007-05-27 | Added | DEFINITION | Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-09 | Deleted | RELATION | is a GO:0010857 (obsolete calcium-dependent protein kinase activity) |
2009-01-15 | Added | RELATION | is a GO:0010857 (obsolete calcium-dependent protein kinase activity) |
2008-04-01 | Updated | RELATION | is a GO:0004674 (protein serine/threonine kinase activity) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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