This term is obsolete.

GO:0010487 JSON

thermospermine synthase activity

Molecular Function

Definition (GO:0010487 GONUTS page)

Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+. PMID:17560575

12,399 annotations

Ancestor Chart

Ancestor chart for GO:0010487
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I940 7227 Q8I940_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.5.1.79
MetaCyc RXN-11190
RHEA 30515

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:17509 5'-S-methyl-5'-thioadenosine
has_participant CHEBI CHEBI:57834 spermidine(3+)
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:59903 thermosperminium(4+)
has_participant CHEBI CHEBI:57443 S-adenosylmethioninaminium

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0010487 based on ALL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term PR S% #Together #Compared
thermospermine synthase activity
16,057.93 100.00 12,340 12,340
spermidine synthase activity
4,633.18 25.27 8,273 28,673
polyamine biosynthetic process
2,071.95 12.90 12,340 95,637
spermidine biosynthetic process
1,778.93 10.50 8,232 74,308
adenosylmethionine decarboxylase activity
140.43 0.59 215 24,585
xylem vessel member cell differentiation
5,823.21 0.27 33 91
spermine synthase activity
335.71 0.26 36 1,722
phloem or xylem histogenesis
143.22 0.21 33 3,700
catalytic activity
32.45 0.20 9,407 4,655,290
auxin polar transport
76.02 0.17 33 6,971
Totals 71697 276482758
No co-occurrence statistics for GO:0010487 based on MANUAL annotations
The top 14 of 14 co-occurring terms
Co-occurring Term PR S% #Together #Compared
thermospermine synthase activity
13,838.56 100.00 102 102
polyamine biosynthetic process
8,253.12 58.58 99 166
sym-norspermidine synthase activity
13,838.56 4.90 5 5
cadaverine aminopropyltransferase activity
10,378.92 2.91 3 4
agmatine aminopropyltransferase activity
10,378.92 2.91 3 4
spermidine synthase activity
209.68 1.10 4 264
xylem vessel member cell differentiation
1,258.05 0.89 1 11
spermine synthase activity
251.61 0.64 1 55
spermidine biosynthetic process
48.73 0.30 2 568
phloem or xylem histogenesis
50.69 0.27 1 273
Totals 226 294446

Change Log

Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:30515
2018-07-13 Deleted XREF RHEA:30518
2011-09-16 Added XREF RHEA:30518
2010-09-03 Deleted DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
2010-09-03 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.
2010-09-03 Added XREF MetaCyc:RXN-11190
2010-09-03 Added XREF EC:2.5.1.79
2008-05-13 Added DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
2008-04-01 Updated RELATION is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Timestamp Action Category Detail
2007-12-10 Added TERM thermospermine synthase activity
Timestamp Action Category Detail
2010-09-03 Deleted DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
2010-09-03 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.
2008-05-13 Added DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
2007-12-27 Added DEFINITION Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:30515
2018-07-13 Deleted XREF RHEA:30518
2011-09-16 Added XREF RHEA:30518
2010-09-03 Added XREF MetaCyc:RXN-11190
2010-09-03 Added XREF EC:2.5.1.79
Timestamp Action Category Detail
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