GO:0010487
JSON
thermospermine synthase activity
Molecular Function
Definition (GO:0010487 GONUTS page)
Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+. PMID:17560575
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.5.1.79 | |
MetaCyc | RXN-11190 | |
RHEA | 30515 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:17509 | 5'-S-methyl-5'-thioadenosine |
has_participant | CHEBI | CHEBI:57834 | spermidine(3+) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:59903 | thermosperminium(4+) |
has_participant | CHEBI | CHEBI:57443 | S-adenosylmethioninaminium |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0010487 based on ALL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
thermospermine synthase activity
|
16,057.93 | 100.00 | 12,340 | 12,340 |
spermidine synthase activity
|
4,633.18 | 25.27 | 8,273 | 28,673 |
polyamine biosynthetic process
|
2,071.95 | 12.90 | 12,340 | 95,637 |
spermidine biosynthetic process
|
1,778.93 | 10.50 | 8,232 | 74,308 |
adenosylmethionine decarboxylase activity
|
140.43 | 0.59 | 215 | 24,585 |
xylem vessel member cell differentiation
|
5,823.21 | 0.27 | 33 | 91 |
spermine synthase activity
|
335.71 | 0.26 | 36 | 1,722 |
phloem or xylem histogenesis
|
143.22 | 0.21 | 33 | 3,700 |
catalytic activity
|
32.45 | 0.20 | 9,407 | 4,655,290 |
auxin polar transport
|
76.02 | 0.17 | 33 | 6,971 |
Totals | 71697 | 276482758 |
No co-occurrence statistics for GO:0010487 based on MANUAL annotations
The top 14 of 14 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
thermospermine synthase activity
|
13,838.56 | 100.00 | 102 | 102 |
polyamine biosynthetic process
|
8,253.12 | 58.58 | 99 | 166 |
sym-norspermidine synthase activity
|
13,838.56 | 4.90 | 5 | 5 |
cadaverine aminopropyltransferase activity
|
10,378.92 | 2.91 | 3 | 4 |
agmatine aminopropyltransferase activity
|
10,378.92 | 2.91 | 3 | 4 |
spermidine synthase activity
|
209.68 | 1.10 | 4 | 264 |
xylem vessel member cell differentiation
|
1,258.05 | 0.89 | 1 | 11 |
spermine synthase activity
|
251.61 | 0.64 | 1 | 55 |
spermidine biosynthetic process
|
48.73 | 0.30 | 2 | 568 |
phloem or xylem histogenesis
|
50.69 | 0.27 | 1 | 273 |
Totals | 226 | 294446 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:30515 |
2018-07-13 | Deleted | XREF | RHEA:30518 |
2011-09-16 | Added | XREF | RHEA:30518 |
2010-09-03 | Deleted | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
2010-09-03 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+. |
2010-09-03 | Added | XREF | MetaCyc:RXN-11190 |
2010-09-03 | Added | XREF | EC:2.5.1.79 |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
2008-04-01 | Updated | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-12-10 | Added | TERM | thermospermine synthase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-09-03 | Deleted | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
2010-09-03 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
2007-12-27 | Added | DEFINITION | Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:30515 |
2018-07-13 | Deleted | XREF | RHEA:30518 |
2011-09-16 | Added | XREF | RHEA:30518 |
2010-09-03 | Added | XREF | MetaCyc:RXN-11190 |
2010-09-03 | Added | XREF | EC:2.5.1.79 |
Timestamp | Action | Category | Detail |
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