This term is obsolete.

GO:0010494 JSON

cytoplasmic stress granule

Cellular Component

Definition (GO:0010494 GONUTS page)

A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. PMID:17284590 PMID:17601829 PMID:17967451 PMID:20368989

60,744 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
stress granule exact
cytoplasmic mRNP granule exact

Ancestor Chart

Ancestor chart for GO:0010494
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0010494 cytoplasmic stress granule Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATP6 6239 A0A2K5ATP6_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
UniProtKB-SubCell SL-0496 Stress granule
Wikipedia Stress_granule

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0010494 based on ALL annotations
The top 100 of 2,223 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cytoplasmic stress granule
3,303.96 100.00 59,975 59,975
stress granule assembly
2,035.06 16.19 10,800 17,534
positive regulation of translation
639.00 12.89 16,724 86,472
mRNA 3'-UTR binding
554.23 9.85 11,559 68,907
regulation of translation at presynapse, modulating synaptic transmission
3,298.20 9.55 5,731 5,741
regulation of mRNA stability
732.93 9.54 8,602 38,777
positive regulation of long-term neuronal synaptic plasticity
3,168.94 9.51 5,727 5,971
translation regulator activity
816.99 7.75 6,085 24,608
intracellular mRNA localization
1,562.42 6.96 4,527 9,573
anterograde dendritic transport of messenger ribonucleoprotein complex
3,228.74 6.93 4,164 4,261
Totals 397015 13247511
No co-occurrence statistics for GO:0010494 based on MANUAL annotations
The top 100 of 1,810 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cytoplasmic stress granule
696.37 100.00 2,027 2,027
stress granule assembly
505.79 27.78 629 866
positive regulation of translation
186.21 10.23 288 1,077
mRNA 3'-UTR binding
109.41 10.07 444 2,826
poly(U) RNA binding
189.84 8.59 226 829
P-body assembly
164.66 8.22 227 960
negative regulation of translation
101.39 7.96 303 2,081
poly(A) binding
126.90 7.82 244 1,339
cytoplasmic translational initiation
182.81 6.88 173 659
regulation of mRNA stability
222.07 6.83 162 508
Totals 10960 235104

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2017-01-21 Deleted SYNONYM P-body
2014-06-20 Added RELATION is a GO:0036464 (cytoplasmic ribonucleoprotein granule)
2014-06-20 Deleted RELATION is a GO:0035770 (ribonucleoprotein granule)
2014-06-20 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2012-08-11 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
2011-09-30 Updated TERM cytoplasmic stress granule
2011-09-30 Added SYNONYM stress granule
2011-09-30 Added SYNONYM P-body
2011-09-30 Added SYNONYM cytoplasmic mRNP granule
Timestamp Action Category Detail
2011-09-30 Updated TERM cytoplasmic stress granule
2007-12-14 Added TERM stress granule
Timestamp Action Category Detail
2017-01-21 Deleted SYNONYM P-body
2011-09-30 Added SYNONYM stress granule
2011-09-30 Added SYNONYM P-body
2011-09-30 Added SYNONYM cytoplasmic mRNP granule
2008-05-13 Added DEFINITION A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
2008-05-12 Deleted DEFINITION A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
2007-12-27 Added DEFINITION A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
Timestamp Action Category Detail
2014-06-20 Added RELATION is a GO:0036464 (cytoplasmic ribonucleoprotein granule)
2014-06-20 Deleted RELATION is a GO:0035770 (ribonucleoprotein granule)
2014-06-20 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2012-08-11 Added RELATION is a GO:0044444 (obsolete cytoplasmic part)
2011-04-03 Deleted RELATION is a GO:0030529 (intracellular ribonucleoprotein complex)
2011-04-03 Deleted RELATION is a GO:0044444 (obsolete cytoplasmic part)
2011-04-03 Added RELATION is a GO:0035770 (ribonucleoprotein granule)
2008-04-01 Updated RELATION is a GO:0030529 (intracellular ribonucleoprotein complex)
2008-04-01 Updated RELATION is a GO:0044444 (obsolete cytoplasmic part)
Timestamp Action Category Detail
2009-02-08 Added XREF Wikipedia:Stress_granule
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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