GO:0010494
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cytoplasmic stress granule
Cellular Component
Definition (GO:0010494 GONUTS page)
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. PMID:17284590 PMID:17601829 PMID:17967451 PMID:20368989
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
cytoplasmic mRNP granule | exact |
stress granule | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0010494 | cytoplasmic stress granule | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 237631 | A0A0D1E8X3_USTMA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1L8G9S0 | 8355 | A0A1L8G9S0_XENLA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4L3K3 | 6945 | A0A1S4L3K3_IXOSC | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A2K5ATM2 | 6239 | A0A2K5ATM2_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATM9 | 6239 | A0A2K5ATM9_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATP6 | 6239 | A0A2K5ATP6_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
UniProtKB-SubCell | SL-0496 | Stress granule |
Wikipedia | Stress_granule |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0010494 based on ALL annotations
The top 100 of 2,251 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cytoplasmic stress granule
|
3,339.54 | 100.00 | 58,373 | 58,373 |
stress granule assembly
|
2,060.03 | 16.02 | 10,383 | 16,832 |
positive regulation of translation
|
641.87 | 12.84 | 16,293 | 84,770 |
mRNA 3'-UTR binding
|
559.45 | 9.85 | 11,260 | 67,215 |
regulation of mRNA stability
|
744.01 | 9.57 | 8,382 | 37,623 |
regulation of translation at presynapse, modulating synaptic transmission
|
3,333.53 | 9.51 | 5,551 | 5,561 |
positive regulation of long-term neuronal synaptic plasticity
|
3,198.88 | 9.47 | 5,549 | 5,793 |
translation regulator activity
|
824.68 | 7.73 | 5,902 | 23,900 |
intracellular mRNA localization
|
1,567.92 | 6.95 | 4,403 | 9,378 |
anterograde dendritic transport of messenger ribonucleoprotein complex
|
3,261.23 | 6.91 | 4,040 | 4,137 |
Totals | 386345 | 12987964 |
No co-occurrence statistics for GO:0010494 based on MANUAL annotations
The top 100 of 1,827 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cytoplasmic stress granule
|
677.40 | 100.00 | 1,907 | 1,907 |
stress granule assembly
|
488.44 | 27.17 | 579 | 803 |
positive regulation of translation
|
187.14 | 10.71 | 284 | 1,028 |
mRNA 3'-UTR binding
|
107.34 | 10.21 | 425 | 2,682 |
poly(U) RNA binding
|
181.11 | 8.27 | 204 | 763 |
P-body assembly
|
159.90 | 7.92 | 203 | 860 |
poly(A) binding
|
122.96 | 7.63 | 222 | 1,223 |
negative regulation of translation
|
90.04 | 7.46 | 277 | 2,084 |
cytoplasmic translational initiation
|
181.21 | 7.10 | 168 | 628 |
regulation of mRNA stability
|
222.39 | 6.85 | 152 | 463 |
Totals | 10226 | 219250 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2017-01-21 | Deleted | SYNONYM | P-body |
2014-06-20 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2014-06-20 | Deleted | RELATION | is a GO:0035770 (ribonucleoprotein granule) |
2014-06-20 | Added | RELATION | is a GO:0036464 (cytoplasmic ribonucleoprotein granule) |
2012-08-11 | Added | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2011-09-30 | Updated | TERM | cytoplasmic stress granule |
2011-09-30 | Added | SYNONYM | cytoplasmic mRNP granule |
2011-09-30 | Added | SYNONYM | stress granule |
2011-09-30 | Added | SYNONYM | P-body |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-09-30 | Updated | TERM | cytoplasmic stress granule |
2007-12-14 | Added | TERM | stress granule |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-01-21 | Deleted | SYNONYM | P-body |
2011-09-30 | Added | SYNONYM | cytoplasmic mRNP granule |
2011-09-30 | Added | SYNONYM | stress granule |
2011-09-30 | Added | SYNONYM | P-body |
2008-05-13 | Added | DEFINITION | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
2008-05-12 | Deleted | DEFINITION | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
2007-12-27 | Added | DEFINITION | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-06-20 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2014-06-20 | Deleted | RELATION | is a GO:0035770 (ribonucleoprotein granule) |
2014-06-20 | Added | RELATION | is a GO:0036464 (cytoplasmic ribonucleoprotein granule) |
2012-08-11 | Added | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2011-04-03 | Deleted | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
2011-04-03 | Added | RELATION | is a GO:0035770 (ribonucleoprotein granule) |
2011-04-03 | Deleted | RELATION | is a GO:0030529 (intracellular ribonucleoprotein complex) |
2008-04-01 | Updated | RELATION | is a GO:0030529 (intracellular ribonucleoprotein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044444 (obsolete cytoplasmic part) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-08 | Added | XREF | Wikipedia:Stress_granule |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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