This term is obsolete.

GO:0010519 JSON

negative regulation of phospholipase activity

Biological Process

Definition (GO:0010519 GONUTS page)

Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.

Restrictions

This term should not be used for direct annotation.

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

6 annotations

Ancestor Chart

Ancestor chart for GO:0010519
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0010519

Child Term Relationship to
GO:0010519
negative regulation of phospholipase A2 activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Describing enzyme functions that catalyse multi-stage reactions Link

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0010519 based on ALL annotations
The top 73 of 73 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of phospholipase activity
48,734,696.00 100.00 4 4
negative regulation of glycine import across plasma membrane
16,244,899.00 25.00 2 6
negative regulation of lipoprotein lipase activity
4,430,427.00 7.14 1 11
negative regulation of MAP kinase activity
1,218,367.40 2.44 2 80
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway
955,582.30 1.92 2 102
negative regulation of cell growth involved in cardiac muscle cell development
515,711.10 1.05 2 189
positive regulation of cardiac muscle contraction
259,227.11 0.53 2 376
relaxation of vascular associated smooth muscle
224,067.56 0.46 2 435
maternal process involved in female pregnancy
223,042.10 0.46 2 437
positive regulation of lipid catabolic process
187,081.38 0.38 2 521
Totals 139 93175771
No co-occurrence statistics for GO:0010519 based on MANUAL annotations
The top 54 of 54 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of phospholipase activity
322,949.75 100.00 4 4
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway
92,271.35 22.22 2 7
negative regulation of lipoprotein lipase activity
29,359.07 7.14 1 11
positive regulation of cardiac muscle contraction
21,529.98 6.25 2 30
relaxation of cardiac muscle
21,529.98 6.25 2 30
negative regulation of cardiac muscle hypertrophy
11,331.57 3.39 2 57
positive regulation of lipid metabolic process
10,764.99 3.03 1 30
adenylate cyclase inhibitor activity
10,417.73 2.94 1 31
negative regulation of G protein-coupled receptor signaling pathway
8,388.31 2.53 2 77
phospholipase inhibitor activity
8,498.68 2.44 1 38
Totals 83 783940

Change Log

Timestamp Action Category Detail
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2023-06-13 Added SUBSET gocheck_do_not_annotate
2010-06-15 Added RELATION negatively regulates GO:0004620 (phospholipase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004620 (phospholipase activity)
2010-06-09 Updated TERM negative regulation of phospholipase activity
2010-06-08 Added RELATION negatively regulates GO:0004620 (phospholipase activity)
2010-06-08 Updated TERM negative regulation of phospholipase activity
2009-02-25 Updated TERM negative regulation of phospholipase activity
2009-02-25 Deleted RELATION negatively regulates GO:0004620 (phospholipase activity)
Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of phospholipase activity
2010-06-08 Updated TERM negative regulation of phospholipase activity
2009-02-25 Updated TERM negative regulation of phospholipase activity
2009-02-22 Updated TERM negative regulation of phospholipase activity
2008-01-28 Added TERM negative regulation of phospholipase activity
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
2008-05-12 Deleted DEFINITION Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
2008-01-28 Added DEFINITION Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0004620 (phospholipase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004620 (phospholipase activity)
2010-06-08 Added RELATION negatively regulates GO:0004620 (phospholipase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0004620 (phospholipase activity)
2009-02-22 Added RELATION negatively regulates GO:0004620 (phospholipase activity)
2008-04-01 Updated RELATION is a GO:0010517 (regulation of phospholipase activity)
2008-04-01 Added RELATION is a GO:0060192 (negative regulation of lipase activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-07-26 Added SUBSET gocheck_obsoletion_candidate
2024-07-26 Deleted SUBSET gocheck_do_not_annotate
2023-06-13 Added SUBSET gocheck_do_not_annotate
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