This term is obsolete.

GO:0010586 JSON

miRNA metabolic process

Biological Process

Definition (GO:0010586 GONUTS page)

The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. PMID:17993620

3,958 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
microRNA metabolic process exact

Ancestor Chart

Ancestor chart for GO:0010586
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0010586

Child Term Relationship to
GO:0010586
miRNA transcription
is_a
miRNA catabolic process
is_a
positive regulation of miRNA metabolic process
positively_regulates
regulation of miRNA metabolic process
regulates
negative regulation of miRNA metabolic process
negatively_regulates

Cross-references

Database ID Description
Reactome R-HSA-203927

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0010586 based on ALL annotations
The top 100 of 258 co-occurring terms
Co-occurring Term PR S% #Together #Compared
miRNA metabolic process
367,634.25 100.00 539 539
siRNA-mediated gene silencing by mRNA destabilization
285,284.20 17.11 97 125
endoribonuclease activity, cleaving miRNA-paired mRNA
163,184.60 13.43 87 196
transposable element silencing by mRNA destabilization
118,348.02 12.75 94 292
positive regulation of cell proliferation involved in kidney development
367,634.25 11.69 63 63
negative regulation of glial cell differentiation
330,870.80 11.54 63 70
regulation of miRNA metabolic process
91,908.56 11.04 89 356
positive regulation of trophoblast cell migration
56,709.54 8.56 87 564
RISC complex assembly
35,223.59 8.08 183 1,910
DEAD/H-box RNA helicase binding
42,419.34 7.21 87 754
Totals 9017 1279131
No co-occurrence statistics for GO:0010586 based on MANUAL annotations
The top 100 of 225 co-occurring terms
Co-occurring Term PR S% #Together #Compared
miRNA metabolic process
24,763.74 100.00 57 57
polyuridylation-dependent mRNA catabolic process
18,572.80 19.67 12 16
uridylyltransferase activity
18,160.07 18.03 11 15
transposable element silencing by mRNA destabilization
11,429.42 16.90 12 26
siRNA-mediated gene silencing by mRNA destabilization
10,318.22 14.08 10 24
miRNA transcription
8,613.47 11.11 8 23
pre-miRNA processing
2,845.52 10.82 37 322
RISC complex assembly
3,700.33 9.92 13 87
regulation of skeletal muscle cell differentiation
4,052.25 8.74 9 55
regulation of miRNA metabolic process
6,190.93 6.94 5 20
Totals 643 17490

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_drosophila 173

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-203927
2024-04-19 Added RELATION is a GO:0016070 (RNA metabolic process)
2024-04-19 Deleted RELATION is a GO:0034660 (obsolete ncRNA metabolic process)
2019-11-09 Added SUBSET goslim_drosophila
2008-08-22 Added RELATION is a GO:0034660 (obsolete ncRNA metabolic process)
2008-08-22 Deleted RELATION is a GO:0016070 (RNA metabolic process)
2008-05-30 Added DEFINITION The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
2008-05-30 Added SYNONYM microRNA metabolic process
2008-05-30 Added RELATION is a GO:0016070 (RNA metabolic process)
2008-05-30 Added TERM miRNA metabolic process
Timestamp Action Category Detail
2008-05-30 Added TERM miRNA metabolic process
Timestamp Action Category Detail
2008-05-30 Added DEFINITION The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
2008-05-30 Added SYNONYM microRNA metabolic process
Timestamp Action Category Detail
2024-04-19 Added RELATION is a GO:0016070 (RNA metabolic process)
2024-04-19 Deleted RELATION is a GO:0034660 (obsolete ncRNA metabolic process)
2008-08-22 Added RELATION is a GO:0034660 (obsolete ncRNA metabolic process)
2008-08-22 Deleted RELATION is a GO:0016070 (RNA metabolic process)
2008-05-30 Added RELATION is a GO:0016070 (RNA metabolic process)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-203927
Timestamp Action Category Detail
2019-11-09 Added SUBSET goslim_drosophila
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