This term is obsolete.

GO:0010826 JSON

negative regulation of centrosome duplication

Biological Process

Definition (GO:0010826 GONUTS page)

Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

5,191 annotations

Ancestor Chart

Ancestor chart for GO:0010826
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0010826

Child Term Relationship to
GO:0010826
negative regulation of centriole replication
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0010826 negative regulation of centrosome duplication Never in Taxon 27896 Planariidae
GO:0010826 negative regulation of centrosome duplication Never in Taxon 33090 Viridiplantae
GO:0010826 negative regulation of centrosome duplication Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein O70191 10090 ATF5_MOUSE GO:0051726 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12130540
NOT-qualified manual protein Q6P788 10116 ATF5_RAT GO:0051726 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q9H0Z9-2 9606 RBM38_HUMAN GO:0051726 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17050675

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0010826 based on ALL annotations
The top 100 of 240 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of centrosome duplication
486,131.62 100.00 401 401
re-entry into mitotic cell cycle
132,035.75 11.42 66 243
protein localization to cell cortex
70,350.76 9.60 89 615
regulation of mRNA stability involved in cellular response to UV
486,131.62 3.99 16 16
filamin binding
14,488.39 2.72 94 3,154
placenta development
12,098.30 2.21 66 2,652
Tat protein binding
10,802.93 1.45 16 720
regulation of vulval development
15,383.91 0.90 5 158
MKS complex
4,274.18 0.86 95 10,805
female sex differentiation
8,357.56 0.81 6 349
Totals 3279 1927594
No co-occurrence statistics for GO:0010826 based on MANUAL annotations
The top 100 of 214 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of centrosome duplication
49,684.58 100.00 26 26
regulation of mRNA stability involved in cellular response to UV
49,684.58 7.69 2 2
regulation of eIF2 alpha phosphorylation by dsRNA
24,842.29 7.14 2 4
chromosome separation
5,678.24 7.02 4 35
regulation of endoribonuclease activity
14,195.59 6.45 2 7
regulation of endodeoxyribonuclease activity
12,421.15 6.25 2 8
minus-end-directed vesicle transport along microtubule
8,280.76 5.56 2 12
re-entry into mitotic cell cycle
7,643.78 5.41 2 13
regulation of protein catabolic process
2,515.67 3.96 4 79
positive regulation of cell cycle G2/M phase transition
3,548.90 3.85 2 28
Totals 185 17118

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:27896 (Planariidae)
2015-06-25 Deleted RELATION is a GO:0010948 (negative regulation of cell cycle process)
2015-06-25 Deleted RELATION is a GO:0010639 (negative regulation of organelle organization)
2014-10-18 Added RELATION is a GO:0046606 (negative regulation of centrosome cycle)
2013-01-25 Added RELATION is a GO:0010948 (negative regulation of cell cycle process)
2009-01-12 Added RELATION is a GO:0010639 (negative regulation of organelle organization)
2008-12-05 Added TERM negative regulation of centrosome duplication
2008-12-05 Added RELATION negatively regulates GO:0051298 (centrosome duplication)
Timestamp Action Category Detail
2008-12-05 Added TERM negative regulation of centrosome duplication
Timestamp Action Category Detail
2008-12-05 Added DEFINITION Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0010948 (negative regulation of cell cycle process)
2015-06-25 Deleted RELATION is a GO:0010639 (negative regulation of organelle organization)
2014-10-18 Added RELATION is a GO:0046606 (negative regulation of centrosome cycle)
2013-01-25 Added RELATION is a GO:0010948 (negative regulation of cell cycle process)
2009-01-12 Added RELATION is a GO:0010639 (negative regulation of organelle organization)
2008-12-05 Added RELATION negatively regulates GO:0051298 (centrosome duplication)
2008-12-05 Added RELATION is a GO:0010824 (regulation of centrosome duplication)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:27896 (Planariidae)
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