GO:0010826
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negative regulation of centrosome duplication
Biological Process
Definition (GO:0010826 GONUTS page)
Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0010826
Child Term | Relationship to GO:0010826 |
---|---|
negative regulation of centriole replication
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0010826 | negative regulation of centrosome duplication | Never in Taxon | 27896 | Planariidae | |
GO:0010826 | negative regulation of centrosome duplication | Never in Taxon | 33090 | Viridiplantae | |
GO:0010826 | negative regulation of centrosome duplication | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | O70191 | 10090 | ATF5_MOUSE | GO:0051726 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12130540 | |
NOT-qualified manual | protein | Q6P788 | 10116 | ATF5_RAT | GO:0051726 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q9H0Z9-2 | 9606 | RBM38_HUMAN | GO:0051726 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17050675 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0010826 based on ALL annotations
The top 100 of 240 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of centrosome duplication
|
486,131.62 | 100.00 | 401 | 401 |
re-entry into mitotic cell cycle
|
132,035.75 | 11.42 | 66 | 243 |
protein localization to cell cortex
|
70,350.76 | 9.60 | 89 | 615 |
regulation of mRNA stability involved in cellular response to UV
|
486,131.62 | 3.99 | 16 | 16 |
filamin binding
|
14,488.39 | 2.72 | 94 | 3,154 |
placenta development
|
12,098.30 | 2.21 | 66 | 2,652 |
Tat protein binding
|
10,802.93 | 1.45 | 16 | 720 |
regulation of vulval development
|
15,383.91 | 0.90 | 5 | 158 |
MKS complex
|
4,274.18 | 0.86 | 95 | 10,805 |
female sex differentiation
|
8,357.56 | 0.81 | 6 | 349 |
Totals | 3279 | 1927594 |
No co-occurrence statistics for GO:0010826 based on MANUAL annotations
The top 100 of 214 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of centrosome duplication
|
49,684.58 | 100.00 | 26 | 26 |
regulation of mRNA stability involved in cellular response to UV
|
49,684.58 | 7.69 | 2 | 2 |
regulation of eIF2 alpha phosphorylation by dsRNA
|
24,842.29 | 7.14 | 2 | 4 |
chromosome separation
|
5,678.24 | 7.02 | 4 | 35 |
regulation of endoribonuclease activity
|
14,195.59 | 6.45 | 2 | 7 |
regulation of endodeoxyribonuclease activity
|
12,421.15 | 6.25 | 2 | 8 |
minus-end-directed vesicle transport along microtubule
|
8,280.76 | 5.56 | 2 | 12 |
re-entry into mitotic cell cycle
|
7,643.78 | 5.41 | 2 | 13 |
regulation of protein catabolic process
|
2,515.67 | 3.96 | 4 | 79 |
positive regulation of cell cycle G2/M phase transition
|
3,548.90 | 3.85 | 2 | 28 |
Totals | 185 | 17118 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33090 (Viridiplantae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:27896 (Planariidae) |
2015-06-25 | Deleted | RELATION | is a GO:0010948 (negative regulation of cell cycle process) |
2015-06-25 | Deleted | RELATION | is a GO:0010639 (negative regulation of organelle organization) |
2014-10-18 | Added | RELATION | is a GO:0046606 (negative regulation of centrosome cycle) |
2013-01-25 | Added | RELATION | is a GO:0010948 (negative regulation of cell cycle process) |
2009-01-12 | Added | RELATION | is a GO:0010639 (negative regulation of organelle organization) |
2008-12-05 | Added | TERM | negative regulation of centrosome duplication |
2008-12-05 | Added | RELATION | negatively regulates GO:0051298 (centrosome duplication) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-12-05 | Added | TERM | negative regulation of centrosome duplication |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-12-05 | Added | DEFINITION | Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-06-25 | Deleted | RELATION | is a GO:0010948 (negative regulation of cell cycle process) |
2015-06-25 | Deleted | RELATION | is a GO:0010639 (negative regulation of organelle organization) |
2014-10-18 | Added | RELATION | is a GO:0046606 (negative regulation of centrosome cycle) |
2013-01-25 | Added | RELATION | is a GO:0010948 (negative regulation of cell cycle process) |
2009-01-12 | Added | RELATION | is a GO:0010639 (negative regulation of organelle organization) |
2008-12-05 | Added | RELATION | negatively regulates GO:0051298 (centrosome duplication) |
2008-12-05 | Added | RELATION | is a GO:0010824 (regulation of centrosome duplication) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33090 (Viridiplantae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:27896 (Planariidae) |
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