This term is obsolete.

GO:0010832 JSON

negative regulation of myotube differentiation

Biological Process

Definition (GO:0010832 GONUTS page)

Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.

958 annotations

Ancestor Chart

Ancestor chart for GO:0010832
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0010832

Child Term Relationship to
GO:0010832
negative regulation of skeletal muscle fiber differentiation
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein O15379 9606 HDAC3_HUMAN GO:0010832 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10983972
NOT-qualified manual protein Q13547 9606 HDAC1_HUMAN GO:0010832 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10983972
NOT-qualified manual protein Q4QQW4 10116 HDAC1_RAT GO:0010832 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q6P6W3 10116 HDAC3_RAT GO:0010832 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0010832 based on ALL annotations
The top 100 of 901 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of myotube differentiation
206,941.38 100.00 942 942
atrioventricular node development
199,950.12 15.10 143 148
negative regulation of cell adhesion molecule production
83,511.88 13.51 159 394
positive regulation of smooth muscle cell differentiation
64,237.21 12.22 158 509
Nkx-2.5 complex
206,941.39 11.46 108 108
septum secundum development
206,941.39 11.46 108 108
right ventricular cardiac muscle tissue morphogenesis
108,493.54 10.38 108 206
negative regulation of cardiac muscle cell apoptotic process
30,427.75 9.20 186 1,265
cardiac muscle cell myoblast differentiation
33,816.73 9.05 159 973
cardiac ventricle morphogenesis
37,745.68 9.03 143 784
Totals 10091 43836
No co-occurrence statistics for GO:0010832 based on MANUAL annotations
The top 100 of 823 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of myotube differentiation
23,922.20 100.00 54 54
regulation of skeletal muscle fiber differentiation
10,632.09 12.50 8 18
protein lysine deacetylase activity
3,805.81 10.94 14 88
regulation of myotube differentiation
5,467.93 9.88 8 35
cellular response to fluid shear stress
3,466.99 8.85 10 69
positive regulation of bone development
10,873.73 8.33 5 11
renal tubule morphogenesis
3,894.31 7.78 7 43
regulation of skeletal muscle fiber development
2,773.59 6.96 8 69
RNA polymerase II transcription repressor complex
2,990.28 6.80 7 56
atrioventricular node development
10,632.09 6.78 4 9
Totals 410 3866

Change Log

Timestamp Action Category Detail
2013-10-30 Added RELATION is a GO:0051154 (negative regulation of striated muscle cell differentiation)
2013-10-25 Deleted RELATION is a GO:2001015 (negative regulation of skeletal muscle cell differentiation)
2011-08-14 Added RELATION is a GO:2001015 (negative regulation of skeletal muscle cell differentiation)
2011-08-14 Deleted RELATION is a GO:0051154 (negative regulation of striated muscle cell differentiation)
2010-12-17 Added DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 Deleted DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-03-11 Deleted RELATION is a GO:0051148 (negative regulation of muscle cell differentiation)
2010-03-11 Added RELATION is a GO:0051154 (negative regulation of striated muscle cell differentiation)
2008-12-08 Added RELATION is a GO:0051148 (negative regulation of muscle cell differentiation)
2008-12-08 Added RELATION negatively regulates GO:0014902 (myotube differentiation)
Timestamp Action Category Detail
2008-12-08 Added TERM negative regulation of myotube differentiation
Timestamp Action Category Detail
2010-12-17 Added DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 Deleted DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2008-12-08 Added DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
Timestamp Action Category Detail
2013-10-30 Added RELATION is a GO:0051154 (negative regulation of striated muscle cell differentiation)
2013-10-25 Deleted RELATION is a GO:2001015 (negative regulation of skeletal muscle cell differentiation)
2011-08-14 Added RELATION is a GO:2001015 (negative regulation of skeletal muscle cell differentiation)
2011-08-14 Deleted RELATION is a GO:0051154 (negative regulation of striated muscle cell differentiation)
2010-03-11 Deleted RELATION is a GO:0051148 (negative regulation of muscle cell differentiation)
2010-03-11 Added RELATION is a GO:0051154 (negative regulation of striated muscle cell differentiation)
2008-12-08 Added RELATION is a GO:0051148 (negative regulation of muscle cell differentiation)
2008-12-08 Added RELATION negatively regulates GO:0014902 (myotube differentiation)
2008-12-08 Added RELATION is a GO:0010830 (regulation of myotube differentiation)
Timestamp Action Category Detail
Timestamp Action Category Detail
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