GO:0010887
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negative regulation of cholesterol storage
Biological Process
Definition (GO:0010887 GONUTS page)
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| negative regulation of cholesterol sequestration | narrow |
Ancestor Chart
Ancestor chart for GO:0010887
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0010887 based on ALL annotations
The top 100 of 588 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of cholesterol storage
|
43,665.68 | 100.00 | 4,538 | 4,538 |
|
positive regulation of fatty acid metabolic process
|
42,913.41 | 81.78 | 3,765 | 3,831 |
|
negative regulation of inflammatory response
|
7,829.94 | 17.41 | 3,889 | 21,688 |
|
regulation of cholesterol efflux
|
22,510.88 | 9.95 | 498 | 966 |
|
hormone-mediated signaling pathway
|
4,187.15 | 9.43 | 3,874 | 40,400 |
|
regulation of cholesterol metabolic process
|
16,890.83 | 9.36 | 499 | 1,290 |
|
intracellular receptor signaling pathway
|
3,756.52 | 8.48 | 3,864 | 44,915 |
|
nuclear receptor activity
|
3,006.98 | 6.82 | 3,960 | 57,505 |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific
|
2,866.39 | 6.48 | 3,770 | 57,431 |
|
positive regulation of cholesterol efflux
|
6,244.64 | 4.35 | 267 | 1,867 |
| Totals | 42869 | 717515 | ||
No co-occurrence statistics for GO:0010887 based on MANUAL annotations
The top 100 of 516 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of cholesterol storage
|
12,168.39 | 100.00 | 116 | 116 |
|
positive regulation of fatty acid metabolic process
|
9,497.28 | 47.76 | 64 | 82 |
|
regulation of cholesterol efflux
|
5,752.33 | 17.93 | 26 | 55 |
|
intracellular receptor signaling pathway
|
2,455.34 | 17.66 | 68 | 337 |
|
regulation of cholesterol metabolic process
|
4,761.54 | 17.09 | 27 | 69 |
|
excitatory synapse pruning
|
12,168.39 | 8.62 | 10 | 10 |
|
positive regulation of complement activation, classical pathway
|
12,168.39 | 8.62 | 10 | 10 |
|
regulation of hippocampal neuron apoptotic process
|
12,168.39 | 8.62 | 10 | 10 |
|
regulation of macrophage inflammatory protein 1 alpha production
|
12,168.39 | 8.62 | 10 | 10 |
|
regulation of toll-like receptor 6 signaling pathway
|
12,168.39 | 8.62 | 10 | 10 |
| Totals | 1353 | 9253 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-02-05 | Added | DEFINITION | Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
| 2009-02-05 | Added | RELATION | negatively regulates GO:0010878 (cholesterol storage) |
| 2009-02-05 | Added | RELATION | is a GO:0010888 (negative regulation of lipid storage) |
| 2009-02-05 | Added | TERM | negative regulation of cholesterol storage |
| 2009-02-05 | Added | SYNONYM | negative regulation of cholesterol sequestration |
| 2009-02-05 | Added | RELATION | is a GO:0010885 (regulation of cholesterol storage) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-02-05 | Added | TERM | negative regulation of cholesterol storage |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-02-05 | Added | DEFINITION | Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
| 2009-02-05 | Added | SYNONYM | negative regulation of cholesterol sequestration |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-02-05 | Added | RELATION | negatively regulates GO:0010878 (cholesterol storage) |
| 2009-02-05 | Added | RELATION | is a GO:0010888 (negative regulation of lipid storage) |
| 2009-02-05 | Added | RELATION | is a GO:0010885 (regulation of cholesterol storage) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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