GO:0015056
JSON
corticotrophin-releasing factor receptor activity
Molecular Function
Definition (GO:0015056 GONUTS page)
Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. PMID:12032352
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0015056 | corticotrophin-releasing factor receptor activity | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A2ARI4 | 10090 | LGR4_MOUSE | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21693646 | |
NOT-qualified manual | protein | B0BLW3 | 8364 | LGR4_XENTR | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | D4AC13 | 10116 | LGR5_RAT | GO:0004930 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | E5DHB5 | 8355 | LGR5A_XENLA | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | E7FE13 | 7955 | LGR4_DANRE | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F1MLX5 | 9913 | LGR4_BOVIN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F1MT22 | 9913 | LGR5_BOVIN | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F7D3V9 | 8364 | LGR5_XENTR | GO:0004930 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | G3QNC0 | 9595 | G3QNC0_GORGO | GO:0007186 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:8910290 | |
NOT-qualified manual | protein | O15529 | 9606 | GPR42_HUMAN | GO:0007186 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12496283 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0015056 based on ALL annotations
The top 100 of 107 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
corticotrophin-releasing factor receptor activity
|
65,481.63 | 100.00 | 2,977 | 2,977 |
corticotropin-releasing hormone receptor activity
|
65,437.52 | 99.63 | 2,968 | 2,970 |
corticotropin-releasing hormone binding
|
35,296.62 | 36.85 | 1,602 | 2,972 |
cellular response to corticotropin-releasing hormone stimulus
|
15,332.61 | 23.42 | 2,977 | 12,714 |
long-term synaptic potentiation
|
11,144.05 | 14.11 | 1,346 | 7,909 |
hormone-mediated signaling pathway
|
4,996.00 | 7.63 | 2,968 | 38,901 |
axon terminus
|
4,584.26 | 6.45 | 1,345 | 19,212 |
G protein-coupled peptide receptor activity
|
4,123.86 | 6.30 | 2,968 | 47,128 |
peptide hormone binding
|
3,685.99 | 5.28 | 1,366 | 24,267 |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
|
2,068.86 | 3.05 | 1,367 | 43,267 |
Totals | 42013 | 82277346 |
No co-occurrence statistics for GO:0015056 based on MANUAL annotations
The top 90 of 90 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
corticotrophin-releasing factor receptor activity
|
36,908.54 | 100.00 | 35 | 35 |
corticotropin-releasing hormone receptor activity
|
34,671.66 | 83.78 | 31 | 33 |
corticotropin-releasing hormone binding
|
15,141.97 | 27.59 | 16 | 39 |
corticotropin secretion
|
28,706.65 | 18.92 | 7 | 9 |
regulation of corticosterone secretion
|
10,334.39 | 13.21 | 7 | 25 |
cellular response to corticotropin-releasing hormone stimulus
|
2,808.26 | 5.83 | 7 | 92 |
general adaptation syndrome, behavioral process
|
4,921.14 | 4.17 | 2 | 15 |
long-term synaptic potentiation
|
1,412.77 | 3.66 | 16 | 418 |
fear response
|
2,733.97 | 3.33 | 2 | 27 |
gastric motility
|
36,908.54 | 2.86 | 1 | 1 |
Totals | 382 | 343550 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-22 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2012-01-12 | Added | RELATION | part of GO:0071376 (cellular response to corticotropin-releasing hormone stimulus) |
2010-06-09 | Updated | TERM | corticotrophin-releasing factor receptor activity |
2010-06-08 | Updated | TERM | corticotrophin-releasing factor receptor activity |
2008-10-10 | Deleted | RELATION | is a GO:0001636 (obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity) |
2008-10-10 | Added | RELATION | is a GO:0004930 (G protein-coupled receptor activity) |
2008-05-13 | Added | DEFINITION | Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. |
2008-04-01 | Updated | RELATION | is a GO:0001636 (obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity) |
2004-01-03 | Updated | DEFINITION | Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-06-09 | Updated | TERM | corticotrophin-releasing factor receptor activity |
2010-06-08 | Updated | TERM | corticotrophin-releasing factor receptor activity |
2003-03-19 | Updated | TERM | corticotrophin-releasing factor receptor activity |
2002-02-06 | Updated | TERM | corticotrophin-releasing factor receptor |
2002-01-09 | Updated | TERM | corticotrophin-releasing factor receptor |
2001-04-03 | Updated | TERM | corticotropin releasing factor receptor |
2001-03-30 | Added | TERM | corticotropin releasing factor receptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. |
2008-05-12 | Deleted | DEFINITION | Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. |
2004-01-03 | Updated | DEFINITION | Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity. |
2003-05-14 | Updated | DEFINITION | The function of combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell function. |
2002-11-27 | Added | DEFINITION | A GPCR that binds the corticotrophin-releasing factor family of ligands, including the urocortins. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-01-12 | Added | RELATION | part of GO:0071376 (cellular response to corticotropin-releasing hormone stimulus) |
2008-10-10 | Deleted | RELATION | is a GO:0001636 (obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity) |
2008-10-10 | Added | RELATION | is a GO:0004930 (G protein-coupled receptor activity) |
2008-04-01 | Updated | RELATION | is a GO:0001636 (obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-22 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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