This term is obsolete.

GO:0015189 JSON

L-lysine transmembrane transporter activity

Molecular Function

Definition (GO:0015189 GONUTS page)

Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.

Secondary IDs

GO:0005293

18,477 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
lysine permease activity related
L-lysine permease related
histidine/arginine/lysine/ornithine porter activity narrow

Ancestor Chart

Ancestor chart for GO:0015189
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0015189

Child Term Relationship to
GO:0015189
GO:0005292
high-affinity lysine transmembrane transporter activity
is_a
GO:0106439
L-lysine:L-arginine antiporter activity
is_a
GO:0015661
L-lysine efflux transmembrane transporter activity
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein Q62011 10090 PDPN_MOUSE GO:0006865 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12032185
NOT-qualified manual protein Q62011 10090 PDPN_MOUSE GO:0015171 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12032185
NOT-qualified manual protein Q62687 10116 S6A18_RAT GO:0015171 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q62687 10116 S6A18_RAT GO:0006865 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q64294 10116 PDPN_RAT GO:0006865 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein Q64294 10116 PDPN_RAT GO:0015171 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein Q86YL7 9606 PDPN_HUMAN GO:0015171 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q86YL7 9606 PDPN_HUMAN GO:0006865 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q95152 9615 PDPN_CANLF GO:0015171 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q95152 9615 PDPN_CANLF GO:0006865 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:32551 L-lysinium(1+)

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0015597 obsolete histidine/arginine/lysine/ornithine porter activity consider GO:0015189

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0015189 based on ALL annotations
The top 100 of 211 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0015189
L-lysine transmembrane transporter activity
16,926.19 100.00 11,707 11,707
GO:1903401
L-lysine transmembrane transport
10,659.52 61.75 11,349 18,021
GO:0061459
L-arginine transmembrane transporter activity
12,310.96 53.38 7,813 10,742
GO:0097638
L-arginine import across plasma membrane
16,453.93 42.63 5,052 5,197
GO:1903826
L-arginine transmembrane transport
8,388.98 39.22 7,640 15,415
GO:1903352
L-ornithine transmembrane transport
12,779.45 37.83 5,048 6,686
GO:0000064
L-ornithine transmembrane transporter activity
5,909.40 24.36 5,224 14,963
GO:0005290
L-histidine transmembrane transporter activity
9,787.37 19.77 2,705 4,678
GO:0005302
L-tyrosine transmembrane transporter activity
9,090.40 17.90 2,478 4,614
GO:0015194
L-serine transmembrane transporter activity
8,527.19 16.63 2,328 4,621
Totals 138635 97049802
No co-occurrence statistics for GO:0015189 based on MANUAL annotations
The top 100 of 103 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0015189
3,282.63 100.00 430 430
GO:0005313
1,192.97 31.49 302 831
GO:0061459
2,638.98 26.74 123 153
GO:0015180
1,803.14 22.24 117 213
GO:1903352
3,282.63 18.60 80 80
GO:0097638
2,854.47 18.10 80 92
GO:0015185
979.77 16.60 117 392
GO:0015812
923.24 16.05 117 416
GO:0000064
900.08 12.98 85 310
GO:0006865
342.25 8.92 164 1,573
Totals 2297 496593

Change Log

Timestamp Action Category Detail
2024-04-04 Added RELATION is a GO:0015101 (organic cation transmembrane transporter activity)
2023-12-15 Deleted RELATION is a GO:1901702 (salt transmembrane transporter activity)
2022-12-24 Deleted RELATION is a GO:0008514 (organic anion transmembrane transporter activity)
2022-12-24 Added RELATION is a GO:1901702 (salt transmembrane transporter activity)
2022-12-02 Deleted RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
2020-11-03 Added RELATION is a GO:0008514 (organic anion transmembrane transporter activity)
2019-04-18 Deleted RELATION is a GO:0015238 (drug transmembrane transporter activity)
2017-11-29 Added RELATION is a GO:0015238 (drug transmembrane transporter activity)
2016-11-28 Added RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
2016-06-22 Deleted RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
Timestamp Action Category Detail
2010-06-09 Updated TERM L-lysine transmembrane transporter activity
2010-06-08 Updated TERM L-lysine transmembrane transporter activity
2007-07-11 Updated TERM L-lysine transmembrane transporter activity
2003-09-05 Updated TERM L-lysine transporter activity
2003-03-19 Updated TERM lysine transporter activity
2002-02-06 Updated TERM lysine transporter
2001-04-03 Updated TERM lysine transporter
2001-03-30 Added TERM lysine transporter
Timestamp Action Category Detail
2015-05-11 Added DEFINITION Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
2015-05-11 Deleted DEFINITION Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
2008-05-13 Added DEFINITION Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
2008-05-12 Deleted DEFINITION Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
2007-08-09 Deleted SYNONYM lysine permease activity
2007-08-09 Deleted SYNONYM L-lysine permease
2007-08-09 Added SYNONYM lysine permease activity
2007-08-09 Added SYNONYM histidine/arginine/lysine/ornithine porter activity
2007-08-09 Added SYNONYM L-lysine permease
2007-08-09 Deleted SYNONYM histidine/arginine/lysine/ornithine porter activity
2007-07-27 Updated DEFINITION Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
2007-07-27 Added SYNONYM L-lysine permease
2007-07-11 Added SYNONYM lysine permease activity
2005-08-10 Added SYNONYM histidine/arginine/lysine/ornithine porter activity
2003-09-05 Updated DEFINITION Enables the directed movement of L-lysine, 2,6-diaminohexanoic acid, into, out of, within or between cells.
2003-03-26 Updated DEFINITION Enables the directed movement of lysine, 2,6-diaminohexanoic acid, into, out of, within or between cells.
2002-11-27 Added DEFINITION Enables the directed movement of lysine, 2,6-diaminohexanoic acid, into, out of, or within a cell.
Timestamp Action Category Detail
2024-04-04 Added RELATION is a GO:0015101 (organic cation transmembrane transporter activity)
2023-12-15 Deleted RELATION is a GO:1901702 (salt transmembrane transporter activity)
2022-12-24 Deleted RELATION is a GO:0008514 (organic anion transmembrane transporter activity)
2022-12-24 Added RELATION is a GO:1901702 (salt transmembrane transporter activity)
2022-12-02 Deleted RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
2020-11-03 Added RELATION is a GO:0008514 (organic anion transmembrane transporter activity)
2019-04-18 Deleted RELATION is a GO:0015238 (drug transmembrane transporter activity)
2017-11-29 Added RELATION is a GO:0015238 (drug transmembrane transporter activity)
2016-11-28 Added RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
2016-06-22 Deleted RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
2014-10-26 Added RELATION part of GO:1903401 (L-lysine transmembrane transport)
2014-10-26 Deleted RELATION part of GO:0015819 (lysine transport)
2012-11-02 Added RELATION is a GO:0008324 (monoatomic cation transmembrane transporter activity)
2010-06-15 Added RELATION part of GO:0015819 (lysine transport)
2010-06-14 Deleted RELATION part of GO:0015819 (lysine transport)
2010-06-08 Added RELATION part of GO:0015819 (lysine transport)
2008-04-01 Updated RELATION is a GO:0015174 (basic amino acid transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0015179 (L-amino acid transmembrane transporter activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
2007-07-11 Added SECONDARY GO:0005293 (lysine permease activity)
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