GO:0015297
JSON
antiporter activity
Molecular Function
Definition (GO:0015297 GONUTS page)
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). PMID:10839820
Secondary IDs
GO:0015300, GO:0099516
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
porter | broad |
exchanger | broad |
antiport | related |
ion antiporter activity | narrow |
solute:solute exchange | related |
solute:solute antiporter activity | exact |
exchange transporter activity | exact |
countertransporter activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0015297
Child Term | Relationship to GO:0015297 |
---|---|
L-lysine:L-arginine antiporter activity
|
is_a |
tetracycline:proton antiporter activity
|
is_a |
monoatomic ion antiporter activity involved in regulation of presynaptic membrane potential
|
is_a |
polyspecific organic cation:proton antiporter activity
|
is_a |
succinate:fumarate antiporter activity
|
is_a |
carnitine:O-acyl-L-carnitine antiporter activity
|
is_a |
broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
|
is_a |
S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity
|
is_a |
solute:inorganic anion antiporter activity
|
is_a |
lysine:cadaverine antiporter activity
|
is_a |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR002528 | Multi antimicrobial extrusion protein |
InterPro | IPR004672 | Na(+)/H(+) antiporter NhaD |
InterPro | IPR004706 | Arsenical-resistance protein Acr3 |
InterPro | IPR004770 | Na+/H+ antiporter NhaC |
InterPro | IPR004847 | Na(+)/H(+) antiporter subunit E1 |
InterPro | IPR005133 | Na+/H+ antiporter subunit G |
InterPro | IPR005663 | Monovalent cation proton antiporter subunit A |
InterPro | IPR006153 | Cation/H+ exchanger, transmembrane domain |
InterPro | IPR045016 | Na(+)/H(+) antiporter NhaD-like |
InterPro | IPR048123 | Na(+),Li(+),K(+)/H(+) antiporter subunit UmpB |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0015363 | obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity | consider GO:0015297 |
GO:0030180 | obsolete solute:solute exchange | consider GO:0015297 |
GO:0015982 | obsolete antiport | replaced_by GO:0015297 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0015297 based on ALL annotations
The top 100 of 2,547 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
antiporter activity
|
339.25 | 100.00 | 584,097 | 584,097 |
xenobiotic transmembrane transporter activity
|
131.46 | 20.14 | 172,569 | 445,332 |
xenobiotic transport
|
122.69 | 17.14 | 143,522 | 396,862 |
sodium:proton antiporter activity
|
217.63 | 14.26 | 90,520 | 141,103 |
sodium ion transport
|
77.53 | 11.02 | 102,530 | 448,661 |
monoatomic ion transport
|
50.64 | 9.99 | 135,380 | 906,918 |
sodium ion transmembrane transport
|
67.95 | 8.80 | 79,204 | 395,410 |
regulation of pH
|
289.06 | 8.20 | 48,606 | 57,045 |
potassium ion transport
|
51.83 | 7.75 | 79,395 | 519,696 |
potassium:proton antiporter activity
|
227.53 | 7.67 | 46,544 | 69,397 |
Totals | 3930125 | 112116216 |
No co-occurrence statistics for GO:0015297 based on MANUAL annotations
The top 100 of 450 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
antiporter activity
|
615.32 | 100.00 | 2,294 | 2,294 |
nucleotide-sugar transmembrane transporter activity
|
599.88 | 13.51 | 311 | 319 |
nucleotide-sugar transmembrane transport
|
605.03 | 12.79 | 294 | 299 |
UDP-galactose transmembrane transporter activity
|
325.50 | 11.75 | 301 | 569 |
UDP-xylose transmembrane transporter activity
|
501.59 | 10.51 | 247 | 303 |
transmembrane transport
|
61.45 | 9.51 | 1,531 | 15,330 |
Golgi apparatus
|
52.49 | 8.48 | 2,140 | 25,086 |
triose-phosphate transmembrane transporter activity
|
597.22 | 7.18 | 165 | 170 |
phosphoglycerate transmembrane transporter activity
|
593.34 | 7.04 | 162 | 168 |
GDP-mannose transmembrane transporter activity
|
606.65 | 6.10 | 140 | 142 |
Totals | 9341 | 94850 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:20.03.07 |
2019-05-04 | Added | XREF | MIPS_funcat:20.03.07 |
2019-04-18 | Added | SECONDARY | GO:0099516 (ion antiporter activity) |
2019-04-18 | Added | SYNONYM | ion antiporter activity |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2730959 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2730692 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2730959 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2731002 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2731002 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2730692 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | antiporter activity |
2002-02-06 | Updated | TERM | antiporter |
2001-04-03 | Updated | TERM | antiporter |
2001-03-30 | Added | TERM | antiporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-18 | Added | SYNONYM | ion antiporter activity |
2012-08-11 | Deleted | DEFINITION | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
2012-08-11 | Added | SYNONYM | solute:solute exchange |
2012-08-11 | Added | SYNONYM | solute:solute antiporter activity |
2012-08-11 | Deleted | SYNONYM | dicarboxylate (succinate/fumarate/malate) antiporter activity |
2012-08-11 | Added | DEFINITION | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out). |
2009-07-30 | Added | SYNONYM | exchange transporter activity |
2009-07-30 | Added | SYNONYM | countertransporter activity |
2009-07-30 | Deleted | SYNONYM | exchange transporter |
2009-07-30 | Deleted | SYNONYM | countertransporter |
2008-05-13 | Added | DEFINITION | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
2008-05-12 | Deleted | DEFINITION | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
2007-09-10 | Deleted | SYNONYM | antiporter activity |
2007-08-09 | Deleted | SYNONYM | exchanger |
2007-08-09 | Deleted | SYNONYM | exchange transporter |
2007-08-09 | Deleted | SYNONYM | dicarboxylate (succinate/fumarate/malate) antiporter activity |
2007-08-09 | Deleted | SYNONYM | countertransporter |
2007-08-09 | Deleted | SYNONYM | antiport |
2007-08-09 | Added | SYNONYM | porter |
2007-08-09 | Deleted | SYNONYM | antiporter activity |
2007-08-09 | Added | SYNONYM | exchanger |
2007-08-09 | Added | SYNONYM | exchange transporter |
2007-08-09 | Added | SYNONYM | dicarboxylate (succinate/fumarate/malate) antiporter activity |
2007-08-09 | Added | SYNONYM | countertransporter |
2007-08-09 | Added | SYNONYM | antiporter activity |
2007-08-09 | Added | SYNONYM | antiport |
2007-08-09 | Deleted | SYNONYM | porter |
2007-07-27 | Updated | DEFINITION | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
2007-07-11 | Added | SYNONYM | antiporter activity |
2007-07-11 | Added | SYNONYM | porter |
2005-08-10 | Added | SYNONYM | antiport |
2005-08-10 | Added | SYNONYM | dicarboxylate (succinate/fumarate/malate) antiporter activity |
2004-04-19 | Added | SYNONYM | countertransporter |
2004-04-19 | Added | SYNONYM | exchanger |
2004-04-19 | Added | SYNONYM | exchange transporter |
2004-04-16 | Deleted | SYNONYM | exchanger |
2004-04-16 | Deleted | SYNONYM | exchange transporter |
2004-04-16 | Deleted | SYNONYM | countertransporter |
2002-11-27 | Updated | DEFINITION | Catalysis of the exchange of one or more molecular species for another across a membrane. |
2001-08-06 | Added | DEFINITION | Catalyze the exchange of one or more molecular species for another across a membrane. |
2001-03-30 | Added | SYNONYM | countertransporter |
2001-03-30 | Added | SYNONYM | exchange transporter |
2001-03-30 | Added | SYNONYM | exchanger |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0015291 (secondary active transmembrane transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:20.03.07 |
2019-05-04 | Added | XREF | MIPS_funcat:20.03.07 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2730959 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2730692 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2730959 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2731002 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-2731002 |
2019-04-01 | Added | XREF | Reactome:R-HSA-2730692 |
2018-12-11 | Added | XREF | reactome:R-HSA-2730959 |
2018-12-11 | Added | XREF | reactome:R-HSA-2730692 |
2018-12-11 | Added | XREF | reactome:R-HSA-2731002 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-18 | Added | SECONDARY | GO:0099516 (ion antiporter activity) |
2012-08-11 | Added | SECONDARY | GO:0015300 (solute:solute antiporter activity) |
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