This term is obsolete.

GO:0015312 JSON

polyamine:proton antiporter activity

Molecular Function

Definition (GO:0015312 GONUTS page)

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).

96 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
polyamine:hydrogen antiporter activity exact

Ancestor Chart

Ancestor chart for GO:0015312
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Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7MB71 9913 AT1B4_BOVIN GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein B4YDY0 10090 B4YDY0_MOUSE GO:0006811 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18624921
NOT-qualified manual protein D4ABB2 10116 D4ABB2_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q8CHM1 10116 AQP11_RAT GO:0006811 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000266, ECO:0000314 from these references: GO_REF:0000096, PMID:16650285
NOT-qualified manual protein Q8NBQ7 9606 AQP11_HUMAN GO:0006811 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16650285
NOT-qualified manual protein Q8VHK5 10090 MLC1_MOUSE GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15367490
NOT-qualified manual protein Q99ME6 10090 AT1B4_MOUSE GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9BDK6 9823 AT1B4_PIG GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q9R193 10116 AT1B4_RAT GO:0098662 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:51349 polyamine macromolecule
has_primary_input CHEBI CHEBI:15378 hydron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0015312 based on ALL annotations
The top 15 of 15 co-occurring terms
Co-occurring Term PR S% #Together #Compared
polyamine:proton antiporter activity
2,108,030.50 100.00 94 94
monoamine:proton antiporter activity
510,708.40 24.23 94 388
spermine transport
73,065.95 3.47 94 2,712
serotonin uptake
29,046.45 1.38 94 6,822
spermidine transport
24,132.85 1.14 94 8,211
polyamine transmembrane transport
5,162.57 0.24 94 38,383
synaptic vesicle membrane
2,022.34 0.10 75 78,178
secretory granule membrane
713.22 0.03 3 8,867
presynapse
392.44 0.02 19 102,060
cytoplasmic vesicle
221.37 0.01 39 371,385
Totals 1093 71021107
No co-occurrence statistics for GO:0015312 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term PR S% #Together #Compared
polyamine:proton antiporter activity
470,511.00 100.00 3 3
monoamine:proton antiporter activity
128,321.19 27.27 3 11
spermine transport
52,279.00 11.11 3 27
serotonin uptake
22,766.66 4.84 3 62
spermidine transport
19,880.75 4.23 3 71
secretory granule membrane
4,056.13 0.86 3 348
synaptic vesicle membrane
964.16 0.20 3 1,464
transmembrane transporter activity
72.83 0.02 2 12,921
Totals 23 14907

Change Log

Timestamp Action Category Detail
2025-01-21 Deleted RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2022-12-02 Added RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2022-12-02 Added RELATION is a GO:0015078 (proton transmembrane transporter activity)
2022-12-02 Deleted RELATION is a GO:0015299 (obsolete solute:proton antiporter activity)
2022-12-02 Added RELATION is a GO:0015297 (antiporter activity)
2022-06-12 Added RELATION is a GO:0015299 (obsolete solute:proton antiporter activity)
2022-06-12 Deleted RELATION is a GO:0015078 (proton transmembrane transporter activity)
2022-06-12 Deleted RELATION is a GO:0005451 (obsolete monoatomic cation:proton antiporter activity)
2022-04-05 Deleted RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2022-04-05 Added RELATION is a GO:0005451 (obsolete monoatomic cation:proton antiporter activity)
Timestamp Action Category Detail
2014-05-16 Updated TERM polyamine:proton antiporter activity
2010-06-09 Updated TERM polyamine:hydrogen antiporter activity
2010-06-08 Updated TERM polyamine:hydrogen antiporter activity
2003-03-19 Updated TERM polyamine:hydrogen antiporter activity
2002-02-06 Updated TERM polyamine:hydrogen antiporter
2001-04-03 Updated TERM polyamine:hydrogen antiporter
2001-03-30 Added TERM polyamine:hydrogen antiporter
Timestamp Action Category Detail
2017-10-13 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
2017-10-13 Added DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
2014-05-16 Deleted SYNONYM polyamine:proton antiporter activity
2014-05-16 Added SYNONYM polyamine:hydrogen antiporter activity
2009-07-30 Deleted SYNONYM polyamine:proton antiporter
2009-07-30 Added SYNONYM polyamine:proton antiporter activity
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
2007-08-09 Added SYNONYM polyamine:proton antiporter
2007-08-09 Deleted SYNONYM polyamine:proton antiporter
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
2004-04-19 Added SYNONYM polyamine:proton antiporter
2004-04-16 Deleted SYNONYM polyamine:proton antiporter
2003-03-26 Added DEFINITION Catalysis of the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
2001-10-01 Added SYNONYM polyamine:proton antiporter
Timestamp Action Category Detail
2025-01-21 Deleted RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2022-12-02 Added RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2022-12-02 Added RELATION is a GO:0015078 (proton transmembrane transporter activity)
2022-12-02 Deleted RELATION is a GO:0015299 (obsolete solute:proton antiporter activity)
2022-12-02 Added RELATION is a GO:0015297 (antiporter activity)
2022-06-12 Added RELATION is a GO:0015299 (obsolete solute:proton antiporter activity)
2022-06-12 Deleted RELATION is a GO:0015078 (proton transmembrane transporter activity)
2022-06-12 Deleted RELATION is a GO:0005451 (obsolete monoatomic cation:proton antiporter activity)
2022-04-05 Deleted RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2022-04-05 Added RELATION is a GO:0005451 (obsolete monoatomic cation:proton antiporter activity)
2022-04-05 Deleted RELATION is a GO:0015299 (obsolete solute:proton antiporter activity)
2022-03-04 Added RELATION is a GO:0015078 (proton transmembrane transporter activity)
2022-03-04 Added RELATION is a GO:0022853 (active monoatomic ion transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0015203 (polyamine transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0015299 (obsolete solute:proton antiporter activity)
Timestamp Action Category Detail
2007-07-11 Deleted XREF TC:2.A.1.2.16
2003-03-19 Deleted XREF TC:2.A.1.2.15
2003-03-19 Added XREF TC:2.A.1.2.16
2001-03-30 Added XREF TC:2.A.1.2.15
Timestamp Action Category Detail
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