This term is obsolete.

GO:0015375 JSON

glycine:sodium symporter activity

Molecular Function

Definition (GO:0015375 GONUTS page)

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).

Secondary IDs

GO:0015656

1,646 annotations

Ancestor Chart

Ancestor chart for GO:0015375
Chart options
Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A2WLC1 39946 CDT3_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6K7I4 10116 A6K7I4_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7MB71 9913 AT1B4_BOVIN GO:0098662 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein B4YDY0 10090 B4YDY0_MOUSE GO:0006811 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18624921
NOT-qualified manual protein B8B2D0 39946 CDT1_ORYSI GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein D4ABB2 10116 D4ABB2_RAT GO:0034220 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q5VRD7 39947 CDT3_ORYSJ GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867
NOT-qualified manual protein Q5VSB5 39947 CDT1_ORYSJ GO:0030001 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867
NOT-qualified manual protein Q62011 10090 PDPN_MOUSE GO:0015171 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12032185
NOT-qualified manual protein Q62011 10090 PDPN_MOUSE GO:0006865 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12032185

Cross-references

Database ID Description
RHEA 68228
Reactome R-HSA-444120
Reactome R-HSA-5660840

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57305 glycine zwitterion
has_participant CHEBI CHEBI:29101 sodium(1+)
has_primary_input CHEBI CHEBI:57305 glycine zwitterion
has_primary_input CHEBI CHEBI:29101 sodium(1+)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0015375 based on ALL annotations
The top 94 of 94 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glycine:sodium symporter activity
122,848.65 100.00 1,613 1,613
glycine transport
24,301.33 19.50 1,503 7,598
glycine import across plasma membrane
34,886.63 6.13 117 412
synaptic transmission, glycinergic
39,036.02 5.57 102 321
neurotransmitter:sodium symporter activity
3,013.81 0.86 21 856
amino acid import across plasma membrane
749.37 0.55 79 12,951
sodium ion transmembrane transport
499.58 0.41 1,608 395,410
regulation of synaptic transmission, glycinergic
11,374.88 0.30 5 54
symporter activity
361.23 0.29 1,482 504,002
positive regulation of L-glutamine import across plasma membrane
122,848.65 0.25 4 4
Totals 13072 185289438
No co-occurrence statistics for GO:0015375 based on MANUAL annotations
The top 59 of 59 co-occurring terms
Co-occurring Term PR S% #Together #Compared
glycine:sodium symporter activity
20,164.76 100.00 70 70
synaptic transmission, glycinergic
9,093.91 23.47 23 51
neurotransmitter:sodium symporter activity
11,397.47 16.25 13 23
glycine import across plasma membrane
2,488.42 10.51 29 235
neurotransmitter transport
2,910.38 9.15 14 97
regulation of synaptic transmission, glycinergic
12,602.97 6.85 5 8
positive regulation of L-glutamine import across plasma membrane
20,164.76 5.71 4 4
neurotransmitter uptake
2,880.68 5.00 5 35
alanine:sodium symporter activity
5,041.19 4.88 4 16
amino acid import
3,840.91 4.60 4 21
Totals 481 303881

Change Log

Timestamp Action Category Detail
2024-04-05 Added XREF RHEA:68228
2024-03-21 Added RELATION is a GO:0005343 (organic acid:sodium symporter activity)
2020-06-02 Deleted RELATION is a GO:0005328 (neurotransmitter:sodium symporter activity)
2019-05-04 Added XREF Reactome:R-HSA-5660840
2019-04-30 Deleted XREF Reactome:R-HSA-5660840
2019-04-29 Added XREF Reactome:R-HSA-5660840
2019-04-28 Deleted XREF Reactome:R-HSA-5660840
2019-04-27 Added XREF Reactome:R-HSA-5660840
2019-04-23 Deleted XREF Reactome:R-HSA-5660840
2019-04-01 Added XREF Reactome:R-HSA-5660840
Timestamp Action Category Detail
2003-03-19 Updated TERM glycine:sodium symporter activity
2002-02-06 Updated TERM glycine:sodium symporter
2001-04-03 Updated TERM glycine:sodium symporter
2001-03-30 Added TERM glycine:sodium symporter
Timestamp Action Category Detail
2017-10-13 Added DEFINITION Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
2017-10-13 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
2003-03-26 Added DEFINITION Catalysis of the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
Timestamp Action Category Detail
2024-03-21 Added RELATION is a GO:0005343 (organic acid:sodium symporter activity)
2020-06-02 Deleted RELATION is a GO:0005328 (neurotransmitter:sodium symporter activity)
2018-02-09 Deleted RELATION is a GO:0005294 (neutral L-amino acid secondary active transmembrane transporter activity)
2018-02-09 Added RELATION is a GO:0005295 (neutral L-amino acid:sodium symporter activity)
2018-02-09 Deleted RELATION is a GO:0005283 (amino acid:sodium symporter activity)
2018-02-09 Deleted RELATION is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity)
2017-11-29 Added RELATION is a GO:0005328 (neurotransmitter:sodium symporter activity)
2016-11-28 Added RELATION is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity)
2016-06-22 Deleted RELATION is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity)
2013-08-29 Added RELATION is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity)
2008-04-01 Updated RELATION is a GO:0005283 (amino acid:sodium symporter activity)
2008-04-01 Updated RELATION is a GO:0005294 (neutral L-amino acid secondary active transmembrane transporter activity)
2008-04-01 Updated RELATION is a GO:0015187 (glycine transmembrane transporter activity)
Timestamp Action Category Detail
2024-04-05 Added XREF RHEA:68228
2019-05-04 Added XREF Reactome:R-HSA-5660840
2019-04-30 Deleted XREF Reactome:R-HSA-5660840
2019-04-29 Added XREF Reactome:R-HSA-5660840
2019-04-28 Deleted XREF Reactome:R-HSA-5660840
2019-04-27 Added XREF Reactome:R-HSA-5660840
2019-04-23 Deleted XREF Reactome:R-HSA-5660840
2019-04-01 Added XREF Reactome:R-HSA-5660840
2019-04-01 Deleted XREF reactome:R-HSA-444120
2019-04-01 Added XREF Reactome:R-HSA-444120
2018-12-11 Added XREF reactome:R-HSA-444120
Timestamp Action Category Detail
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