GO:0015375
JSON
glycine:sodium symporter activity
Molecular Function
Definition (GO:0015375 GONUTS page)
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
Secondary IDs
GO:0015656
Ancestor Chart
Ancestor chart for GO:0015375
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A2WLC1 | 39946 | CDT3_ORYSI | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6K7I4 | 10116 | A6K7I4_RAT | GO:0034220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7MB71 | 9913 | AT1B4_BOVIN | GO:0098662 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | B4YDY0 | 10090 | B4YDY0_MOUSE | GO:0006811 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18624921 | |
NOT-qualified manual | protein | B8B2D0 | 39946 | CDT1_ORYSI | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | D4ABB2 | 10116 | D4ABB2_RAT | GO:0034220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q5VRD7 | 39947 | CDT3_ORYSJ | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867 | |
NOT-qualified manual | protein | Q5VSB5 | 39947 | CDT1_ORYSJ | GO:0030001 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:23888867 | |
NOT-qualified manual | protein | Q62011 | 10090 | PDPN_MOUSE | GO:0015171 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12032185 | |
NOT-qualified manual | protein | Q62011 | 10090 | PDPN_MOUSE | GO:0006865 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12032185 |
Cross-references
Database | ID | Description |
---|---|---|
RHEA | 68228 | |
Reactome | R-HSA-444120 | |
Reactome | R-HSA-5660840 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57305 | glycine zwitterion |
has_participant | CHEBI | CHEBI:29101 | sodium(1+) |
has_primary_input | CHEBI | CHEBI:57305 | glycine zwitterion |
has_primary_input | CHEBI | CHEBI:29101 | sodium(1+) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0015375 based on ALL annotations
The top 94 of 94 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycine:sodium symporter activity
|
122,848.65 | 100.00 | 1,613 | 1,613 |
glycine transport
|
24,301.33 | 19.50 | 1,503 | 7,598 |
glycine import across plasma membrane
|
34,886.63 | 6.13 | 117 | 412 |
synaptic transmission, glycinergic
|
39,036.02 | 5.57 | 102 | 321 |
neurotransmitter:sodium symporter activity
|
3,013.81 | 0.86 | 21 | 856 |
amino acid import across plasma membrane
|
749.37 | 0.55 | 79 | 12,951 |
sodium ion transmembrane transport
|
499.58 | 0.41 | 1,608 | 395,410 |
regulation of synaptic transmission, glycinergic
|
11,374.88 | 0.30 | 5 | 54 |
symporter activity
|
361.23 | 0.29 | 1,482 | 504,002 |
positive regulation of L-glutamine import across plasma membrane
|
122,848.65 | 0.25 | 4 | 4 |
Totals | 13072 | 185289438 |
No co-occurrence statistics for GO:0015375 based on MANUAL annotations
The top 59 of 59 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glycine:sodium symporter activity
|
20,164.76 | 100.00 | 70 | 70 |
synaptic transmission, glycinergic
|
9,093.91 | 23.47 | 23 | 51 |
neurotransmitter:sodium symporter activity
|
11,397.47 | 16.25 | 13 | 23 |
glycine import across plasma membrane
|
2,488.42 | 10.51 | 29 | 235 |
neurotransmitter transport
|
2,910.38 | 9.15 | 14 | 97 |
regulation of synaptic transmission, glycinergic
|
12,602.97 | 6.85 | 5 | 8 |
positive regulation of L-glutamine import across plasma membrane
|
20,164.76 | 5.71 | 4 | 4 |
neurotransmitter uptake
|
2,880.68 | 5.00 | 5 | 35 |
alanine:sodium symporter activity
|
5,041.19 | 4.88 | 4 | 16 |
amino acid import
|
3,840.91 | 4.60 | 4 | 21 |
Totals | 481 | 303881 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-05 | Added | XREF | RHEA:68228 |
2024-03-21 | Added | RELATION | is a GO:0005343 (organic acid:sodium symporter activity) |
2020-06-02 | Deleted | RELATION | is a GO:0005328 (neurotransmitter:sodium symporter activity) |
2019-05-04 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5660840 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5660840 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5660840 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5660840 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | glycine:sodium symporter activity |
2002-02-06 | Updated | TERM | glycine:sodium symporter |
2001-04-03 | Updated | TERM | glycine:sodium symporter |
2001-03-30 | Added | TERM | glycine:sodium symporter |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-10-13 | Added | DEFINITION | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). |
2017-10-13 | Deleted | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). |
2007-07-27 | Updated | DEFINITION | Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). |
2003-03-26 | Added | DEFINITION | Catalysis of the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-21 | Added | RELATION | is a GO:0005343 (organic acid:sodium symporter activity) |
2020-06-02 | Deleted | RELATION | is a GO:0005328 (neurotransmitter:sodium symporter activity) |
2018-02-09 | Deleted | RELATION | is a GO:0005294 (neutral L-amino acid secondary active transmembrane transporter activity) |
2018-02-09 | Added | RELATION | is a GO:0005295 (neutral L-amino acid:sodium symporter activity) |
2018-02-09 | Deleted | RELATION | is a GO:0005283 (amino acid:sodium symporter activity) |
2018-02-09 | Deleted | RELATION | is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity) |
2017-11-29 | Added | RELATION | is a GO:0005328 (neurotransmitter:sodium symporter activity) |
2016-11-28 | Added | RELATION | is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity) |
2016-06-22 | Deleted | RELATION | is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity) |
2013-08-29 | Added | RELATION | is a GO:0015296 (monoatomic anion:monoatomic cation symporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0005283 (amino acid:sodium symporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0005294 (neutral L-amino acid secondary active transmembrane transporter activity) |
2008-04-01 | Updated | RELATION | is a GO:0015187 (glycine transmembrane transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-05 | Added | XREF | RHEA:68228 |
2019-05-04 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-30 | Deleted | XREF | Reactome:R-HSA-5660840 |
2019-04-29 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-28 | Deleted | XREF | Reactome:R-HSA-5660840 |
2019-04-27 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-23 | Deleted | XREF | Reactome:R-HSA-5660840 |
2019-04-01 | Added | XREF | Reactome:R-HSA-5660840 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-444120 |
2019-04-01 | Added | XREF | Reactome:R-HSA-444120 |
2018-12-11 | Added | XREF | reactome:R-HSA-444120 |
Timestamp | Action | Category | Detail |
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