Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
GO:0016041
JSON
glutamate synthase (ferredoxin) activity
Molecular Function
Definition (GO:0016041 GONUTS page)
Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.
Comments
Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
glutamate synthase (ferredoxin-dependent) | related |
ferredoxin-glutamate synthase activity | related |
ferredoxin-dependent glutamate synthase activity | related |
L-glutamate:ferredoxin oxidoreductase (transaminating) | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.4.7.1 | |
MetaCyc | GLUTAMATE-SYNTHASE-FERREDOXIN-RXN | |
MetaCyc | PWY-4341 | |
RHEA | 12128 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:29985 | L-glutamate(1-) |
has_participant | CHEBI | CHEBI:16810 | 2-oxoglutarate(2-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:33737 | di-mu-sulfido-diiron(2+) |
has_participant | CHEBI | CHEBI:58359 | L-glutamine zwitterion |
has_participant | CHEBI | CHEBI:33738 | di-mu-sulfido-diiron(1+) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016041 based on ALL annotations
The top 50 of 50 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glutamate synthase (ferredoxin) activity
|
118,230.82 | 100.00 | 1,676 | 1,676 |
ammonia assimilation cycle
|
3,884.77 | 3.24 | 1,160 | 35,304 |
glutamate synthase activity
|
2,980.69 | 2.52 | 1,591 | 63,108 |
glutamate biosynthetic process
|
1,409.86 | 1.19 | 1,593 | 133,589 |
3 iron, 4 sulfur cluster binding
|
1,144.59 | 0.96 | 1,181 | 121,992 |
glutamate synthase (NADH) activity
|
772.12 | 0.49 | 32 | 4,900 |
glutamate synthase (NADPH) activity
|
508.28 | 0.40 | 100 | 23,261 |
L-glutamate biosynthetic process
|
735.33 | 0.36 | 14 | 2,251 |
dihydropyrimidine dehydrogenase (NAD+) activity
|
42.58 | 0.02 | 1 | 2,777 |
response to sucrose
|
31.40 | 0.02 | 1 | 3,765 |
Totals | 10505 | 177877703 |
No co-occurrence statistics for GO:0016041 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
glutamate synthase (ferredoxin) activity
|
470,511.00 | 100.00 | 3 | 3 |
L-glutamate biosynthetic process
|
52,279.00 | 9.09 | 1 | 9 |
glutamate synthase activity
|
5,881.39 | 1.22 | 1 | 80 |
response to sucrose
|
3,075.24 | 0.65 | 1 | 153 |
photorespiration
|
2,977.92 | 0.63 | 1 | 158 |
ammonia assimilation cycle
|
2,412.88 | 0.51 | 1 | 195 |
glutamate biosynthetic process
|
1,153.21 | 0.24 | 1 | 408 |
apoplast
|
928.03 | 0.20 | 1 | 507 |
chloroplast envelope
|
785.49 | 0.17 | 2 | 1,198 |
chloroplast stroma
|
351.92 | 0.07 | 2 | 2,674 |
Totals | 23 | 284194 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | L-glutamate:ferredoxin oxidoreductase (transaminating) |
2020-10-08 | Deleted | SYNONYM | glutamate synthase (ferredoxin-dependent) |
2020-10-08 | Deleted | SYNONYM | ferredoxin-dependent glutamate synthase activity |
2020-10-08 | Added | SYNONYM | glutamate synthase (ferredoxin-dependent) |
2020-10-08 | Added | SYNONYM | ferredoxin-glutamate synthase activity |
2020-10-08 | Deleted | SYNONYM | ferredoxin-glutamate synthase activity |
2020-10-08 | Deleted | SYNONYM | L-glutamate:ferredoxin oxidoreductase (transaminating) |
2020-10-08 | Added | SYNONYM | ferredoxin-dependent glutamate synthase activity |
2020-06-22 | Added | XREF | RHEA:12128 |
2012-04-27 | Deleted | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | glutamate synthase (ferredoxin) activity |
2002-02-06 | Updated | TERM | glutamate synthase (ferredoxin) |
2001-04-03 | Updated | TERM | glutamate synthase (ferredoxin) |
2001-03-30 | Added | TERM | glutamate synthase (ferredoxin) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | L-glutamate:ferredoxin oxidoreductase (transaminating) |
2020-10-08 | Deleted | SYNONYM | glutamate synthase (ferredoxin-dependent) |
2020-10-08 | Deleted | SYNONYM | ferredoxin-dependent glutamate synthase activity |
2020-10-08 | Added | SYNONYM | glutamate synthase (ferredoxin-dependent) |
2020-10-08 | Added | SYNONYM | ferredoxin-glutamate synthase activity |
2020-10-08 | Deleted | SYNONYM | ferredoxin-glutamate synthase activity |
2020-10-08 | Deleted | SYNONYM | L-glutamate:ferredoxin oxidoreductase (transaminating) |
2020-10-08 | Added | SYNONYM | ferredoxin-dependent glutamate synthase activity |
2012-04-27 | Deleted | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. |
2012-04-27 | Added | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. |
2009-04-29 | Deleted | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin. |
2009-04-29 | Added | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin. |
2007-11-08 | Added | SYNONYM | ferredoxin-glutamate synthase activity |
2007-11-08 | Added | SYNONYM | L-glutamate:ferredoxin oxidoreductase (transaminating) |
2007-11-08 | Added | SYNONYM | glutamate synthase (ferredoxin-dependent) |
2007-09-06 | Added | SYNONYM | ferredoxin-dependent glutamate synthase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0015930 (glutamate synthase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016643 (oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:12128 |
2009-05-21 | Added | XREF | MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN |
2009-05-21 | Deleted | XREF | MetaCyc:GLUTAMATE-SYNTHASE-(FERREDOXIN)-RXN |
2007-07-19 | Added | XREF | MetaCyc:PWY-4341 |
2003-10-27 | Added | XREF | MetaCyc:GLUTAMATE-SYNTHASE-(FERREDOXIN)-RXN |
2001-03-30 | Added | XREF | EC:1.4.7.1 |
Timestamp | Action | Category | Detail |
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