GO:0016152
JSON
mercury (II) reductase (NADP+) activity
Molecular Function
Definition (GO:0016152 GONUTS page)
Catalysis of the reaction: H+ + Hg + NADP+ = Hg2+ + NADPH.
Secondary IDs
GO:0018692
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
mer A | related |
mercuric reductase activity | related |
mercurate(II) reductase activity | related |
reduced NADP:mercuric ion oxidoreductase activity | related |
Hg:NADP+ oxidoreductase activity | related |
mercury reductase activity | related |
mercuric ion reductase activity | related |
mercury(II) reductase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A6K252 | 10116 | A6K252_RAT | GO:0016723 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.16.1.1 | |
InterPro | IPR021179 | Mercury(II) reductase |
KEGG_REACTION | R02807 | |
MetaCyc | MERCURY-II-REDUCTASE-RXN | |
RHEA | 23856 | |
UM-BBD_reactionID | r0406 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57783 | NADPH(4-) |
has_participant | CHEBI | CHEBI:16793 | mercury(2+) |
has_participant | CHEBI | CHEBI:58349 | NADP(3-) |
has_participant | CHEBI | CHEBI:16170 | mercury(0) |
has_participant | CHEBI | CHEBI:15378 | hydron |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016152 based on ALL annotations
The top 40 of 40 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mercury (II) reductase (NADP+) activity
|
32,564.48 | 100.00 | 6,085 | 6,085 |
detoxification of mercury ion
|
31,907.66 | 74.68 | 4,615 | 4,710 |
mercury ion binding
|
14,570.98 | 39.16 | 4,615 | 10,314 |
response to mercury ion
|
8,883.70 | 25.00 | 4,558 | 16,708 |
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
|
3,684.23 | 11.17 | 5,456 | 48,225 |
NAD(P)H dehydrogenase (quinone) activity
|
1,617.94 | 4.96 | 5,914 | 119,032 |
alkylmercury lyase activity
|
891.69 | 0.86 | 75 | 2,739 |
NADP binding
|
169.97 | 0.52 | 4,615 | 884,170 |
flavin adenine dinucleotide binding
|
115.12 | 0.35 | 5,999 | 1,696,922 |
nucleotide binding
|
83.39 | 0.26 | 4,932 | 1,925,949 |
Totals | 58081 | 184731995 |
No co-occurrence statistics for GO:0016152 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Totals | 0 | 0 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-13 | Updated | TERM | mercury (II) reductase (NADP+) activity |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: H+ + Hg + NADP+ = Hg2+ + NADPH. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH. |
2020-10-08 | Added | SYNONYM | mercuric reductase activity |
2020-10-08 | Added | SYNONYM | reduced NADP:mercuric ion oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | reduced NADP:mercuric ion oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | mercury(II) reductase activity |
2020-10-08 | Deleted | SYNONYM | mercury reductase activity |
2020-10-08 | Deleted | SYNONYM | mercuric ion reductase activity |
2020-10-08 | Deleted | SYNONYM | mercurate(II) reductase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-13 | Updated | TERM | mercury (II) reductase (NADP+) activity |
2003-03-19 | Updated | TERM | mercury (II) reductase activity |
2002-02-06 | Updated | TERM | mercury (II) reductase |
2001-04-03 | Updated | TERM | mercury (II) reductase |
2001-03-30 | Added | TERM | mercury (II) reductase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: H+ + Hg + NADP+ = Hg2+ + NADPH. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH. |
2020-10-08 | Added | SYNONYM | mercuric reductase activity |
2020-10-08 | Added | SYNONYM | reduced NADP:mercuric ion oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | reduced NADP:mercuric ion oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | mercury(II) reductase activity |
2020-10-08 | Deleted | SYNONYM | mercury reductase activity |
2020-10-08 | Deleted | SYNONYM | mercuric ion reductase activity |
2020-10-08 | Deleted | SYNONYM | mercurate(II) reductase activity |
2020-10-08 | Deleted | SYNONYM | Hg:NADP+ oxidoreductase activity |
2020-10-08 | Added | SYNONYM | mercury(II) reductase activity |
2020-10-08 | Deleted | SYNONYM | mercuric reductase activity |
2020-10-08 | Added | SYNONYM | mercury reductase activity |
2020-10-08 | Added | SYNONYM | mercuric ion reductase activity |
2020-10-08 | Added | SYNONYM | Hg:NADP+ oxidoreductase activity |
2020-10-08 | Added | SYNONYM | mercurate(II) reductase activity |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: Hg + NADP+ + H+ = Hg2+ + NADPH + H+. |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: Hg + NADP+ + H+ = Hg2+ + NADPH + H+. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: Hg + NADP+ + H+ = Hg2+ + NADPH + H+. |
2007-11-08 | Added | SYNONYM | mercuric ion reductase activity |
2007-11-08 | Added | SYNONYM | mercury reductase activity |
2007-11-08 | Added | SYNONYM | mercury(II) reductase activity |
2007-11-08 | Added | SYNONYM | reduced NADP:mercuric ion oxidoreductase activity |
2007-11-08 | Added | SYNONYM | Hg:NADP+ oxidoreductase activity |
2007-11-08 | Added | SYNONYM | mercurate(II) reductase activity |
2007-11-08 | Added | SYNONYM | mer A |
2007-09-06 | Deleted | SYNONYM | mercuric reductase |
2007-09-06 | Added | SYNONYM | mercuric reductase activity |
2007-08-09 | Deleted | SYNONYM | mercuric reductase |
2007-08-09 | Added | SYNONYM | mercuric reductase |
2004-04-19 | Added | SYNONYM | mercuric reductase |
2004-04-16 | Deleted | SYNONYM | mercuric reductase |
2003-10-27 | Added | SYNONYM | mercuric reductase |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: Hg + NADP+ + H+ = Hg2+ + NADPH + H+. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016723 (oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R02807 |
2019-06-20 | Added | XREF | KEGG_REACTION:R02807 |
2018-07-13 | Deleted | XREF | RHEA:23859 |
2018-07-13 | Added | XREF | RHEA:23856 |
2011-05-03 | Added | XREF | UM-BBD_reactionID:r0406 |
2011-05-03 | Deleted | XREF | UM-BBD_enzymeID:e0056 |
2010-10-11 | Added | XREF | RHEA:23859 |
2010-10-11 | Added | XREF | KEGG:R02807 |
2009-05-21 | Added | XREF | MetaCyc:MERCURY-II-REDUCTASE-RXN |
2009-05-21 | Deleted | XREF | MetaCyc:MERCURY-(II)-REDUCTASE-RXN |
2003-10-27 | Added | XREF | UM-BBD_enzymeID:e0056 |
2003-10-27 | Added | XREF | MetaCyc:MERCURY-(II)-REDUCTASE-RXN |
2001-03-30 | Added | XREF | EC:1.16.1.1 |
Timestamp | Action | Category | Detail |
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