GO:0016655
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oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Molecular Function
Definition (GO:0016655 GONUTS page)
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016655
Child Term | Relationship to GO:0016655 |
---|---|
NAD(P)H dehydrogenase (quinone) activity
|
is_a |
p-benzoquinone reductase (NADPH) activity
|
is_a |
2-hydroxy-1,4-benzoquinone reductase activity
|
is_a |
NADH dehydrogenase (ubiquinone) activity
|
is_a |
NADPH:quinone reductase activity
|
is_a |
NADH:ubiquinone reductase (non-electrogenic) activity
|
is_a |
NADH:menaquinone oxidoreductase activity
|
is_a |
monodehydroascorbate reductase (NADH) activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.6.5.- | |
InterPro | IPR008703 | Na(+)-translocating NADH-quinone reductase subunit A |
InterPro | IPR010204 | Na(+)-translocating NADH-quinone reductase subunit C |
InterPro | IPR010205 | Na(+)-translocating NADH-quinone reductase subunit F |
InterPro | IPR010966 | Na(+)-translocating NADH-quinone reductase subunit B |
InterPro | IPR010967 | Na(+)-translocating NADH-quinone reductase subunit E |
InterPro | IPR011292 | Na(+)-translocating NADH-quinone reductase subunit D |
InterPro | IPR018922 | NAD(P)H-quinone oxidoreductase subunit M |
InterPro | IPR019654 | NAD(P)H-quinone oxidoreductase subunit L |
InterPro | IPR020874 | NAD(P)H-quinone oxidoreductase, subunit N |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016655 based on ALL annotations
The top 100 of 372 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
|
964.39 | 100.00 | 202,137 | 202,137 |
photosynthesis, light reaction
|
307.58 | 20.61 | 74,421 | 233,344 |
quinone binding
|
193.51 | 17.74 | 122,315 | 609,580 |
thylakoid
|
116.35 | 10.50 | 90,497 | 750,100 |
chloroplast thylakoid membrane
|
117.60 | 10.31 | 80,871 | 663,181 |
oxidoreductase activity, acting on NAD(P)H as acceptor
|
866.17 | 9.93 | 20,292 | 22,593 |
NADH dehydrogenase activity
|
107.62 | 8.55 | 54,073 | 484,536 |
sodium ion transport
|
88.47 | 6.78 | 41,669 | 454,207 |
NADH dehydrogenase complex
|
139.43 | 6.38 | 20,711 | 143,250 |
NADH dehydrogenase (ubiquinone) activity
|
63.19 | 5.58 | 55,373 | 845,128 |
Totals | 1600601 | 165664683 |
No co-occurrence statistics for GO:0016655 based on MANUAL annotations
The top 100 of 183 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
|
19,572.71 | 100.00 | 66 | 66 |
cellular response to jasmonic acid stimulus
|
13,048.48 | 19.18 | 14 | 21 |
daunorubicin metabolic process
|
4,644.37 | 12.61 | 14 | 59 |
androsterone dehydrogenase activity
|
4,419.64 | 12.28 | 14 | 62 |
cellular response to prostaglandin D stimulus
|
9,271.29 | 11.84 | 9 | 19 |
Delta4-3-oxosteroid 5beta-reductase activity
|
19,572.71 | 10.61 | 7 | 7 |
cellular response to corticosteroid stimulus
|
19,572.71 | 10.61 | 7 | 7 |
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
|
19,572.71 | 10.61 | 7 | 7 |
ketosteroid monooxygenase activity
|
3,382.94 | 10.53 | 14 | 81 |
negative regulation of retinoic acid biosynthetic process
|
12,455.36 | 10.00 | 7 | 11 |
Totals | 551 | 12282 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:1.6.5 |
2021-01-04 | Added | XREF | EC:1.6.5.- |
2013-01-13 | Added | SYNONYM | oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor |
2013-01-13 | Updated | TERM | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor |
2008-05-13 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
2008-05-12 | Deleted | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
2008-04-01 | Updated | RELATION | is a GO:0016651 (oxidoreductase activity, acting on NAD(P)H) |
2006-02-09 | Deleted | XREF | EC:1.6.5.- |
2006-02-09 | Added | XREF | EC:1.6.5 |
2003-09-25 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-01-13 | Updated | TERM | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor |
2003-03-25 | Updated | TERM | oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor |
2003-03-19 | Updated | TERM | oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor activity |
2002-02-06 | Updated | TERM | oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor |
2001-04-03 | Updated | TERM | oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor |
2001-03-30 | Added | TERM | oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-01-13 | Added | SYNONYM | oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor |
2008-05-13 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
2008-05-12 | Deleted | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
2003-09-25 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016651 (oxidoreductase activity, acting on NAD(P)H) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Deleted | XREF | EC:1.6.5 |
2021-01-04 | Added | XREF | EC:1.6.5.- |
2006-02-09 | Deleted | XREF | EC:1.6.5.- |
2006-02-09 | Added | XREF | EC:1.6.5 |
2001-03-30 | Added | XREF | EC:1.6.5.- |
Timestamp | Action | Category | Detail |
---|
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