This term is obsolete.

GO:0016655 JSON

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

Molecular Function

Definition (GO:0016655 GONUTS page)

Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.

1,405,669 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor related

Ancestor Chart

Ancestor chart for GO:0016655
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016655

Child Term Relationship to
GO:0016655
NAD(P)H dehydrogenase (quinone) activity
is_a
p-benzoquinone reductase (NADPH) activity
is_a
2-hydroxy-1,4-benzoquinone reductase activity
is_a
NADH dehydrogenase (ubiquinone) activity
is_a
NADPH:quinone reductase activity
is_a
NADH:ubiquinone reductase (non-electrogenic) activity
is_a
NADH:menaquinone oxidoreductase activity
is_a
monodehydroascorbate reductase (NADH) activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
EC 1.6.5.-
InterPro IPR008703 Na(+)-translocating NADH-quinone reductase subunit A
InterPro IPR010204 Na(+)-translocating NADH-quinone reductase subunit C
InterPro IPR010205 Na(+)-translocating NADH-quinone reductase subunit F
InterPro IPR010966 Na(+)-translocating NADH-quinone reductase subunit B
InterPro IPR010967 Na(+)-translocating NADH-quinone reductase subunit E
InterPro IPR011292 Na(+)-translocating NADH-quinone reductase subunit D
InterPro IPR018922 NAD(P)H-quinone oxidoreductase subunit M
InterPro IPR019654 NAD(P)H-quinone oxidoreductase subunit L
InterPro IPR020874 NAD(P)H-quinone oxidoreductase, subunit N

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016655 based on ALL annotations
The top 100 of 372 co-occurring terms
Co-occurring Term PR S% #Together #Compared
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
964.39 100.00 202,137 202,137
photosynthesis, light reaction
307.58 20.61 74,421 233,344
quinone binding
193.51 17.74 122,315 609,580
thylakoid
116.35 10.50 90,497 750,100
chloroplast thylakoid membrane
117.60 10.31 80,871 663,181
oxidoreductase activity, acting on NAD(P)H as acceptor
866.17 9.93 20,292 22,593
NADH dehydrogenase activity
107.62 8.55 54,073 484,536
sodium ion transport
88.47 6.78 41,669 454,207
NADH dehydrogenase complex
139.43 6.38 20,711 143,250
NADH dehydrogenase (ubiquinone) activity
63.19 5.58 55,373 845,128
Totals 1600601 165664683
No co-occurrence statistics for GO:0016655 based on MANUAL annotations
The top 100 of 183 co-occurring terms
Co-occurring Term PR S% #Together #Compared
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
19,572.71 100.00 66 66
cellular response to jasmonic acid stimulus
13,048.48 19.18 14 21
daunorubicin metabolic process
4,644.37 12.61 14 59
androsterone dehydrogenase activity
4,419.64 12.28 14 62
cellular response to prostaglandin D stimulus
9,271.29 11.84 9 19
Delta4-3-oxosteroid 5beta-reductase activity
19,572.71 10.61 7 7
cellular response to corticosteroid stimulus
19,572.71 10.61 7 7
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
19,572.71 10.61 7 7
ketosteroid monooxygenase activity
3,382.94 10.53 14 81
negative regulation of retinoic acid biosynthetic process
12,455.36 10.00 7 11
Totals 551 12282

Change Log

Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:1.6.5
2021-01-04 Added XREF EC:1.6.5.-
2013-01-13 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2013-01-13 Updated TERM oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
2008-04-01 Updated RELATION is a GO:0016651 (oxidoreductase activity, acting on NAD(P)H)
2006-02-09 Deleted XREF EC:1.6.5.-
2006-02-09 Added XREF EC:1.6.5
2003-09-25 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
Timestamp Action Category Detail
2013-01-13 Updated TERM oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
2003-03-25 Updated TERM oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2003-03-19 Updated TERM oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor activity
2002-02-06 Updated TERM oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor
2001-04-03 Updated TERM oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor
2001-03-30 Added TERM oxidoreductase, acting on NADH or NADPH, quinone or similar compound as acceptor
Timestamp Action Category Detail
2013-01-13 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
2003-09-25 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016651 (oxidoreductase activity, acting on NAD(P)H)
Timestamp Action Category Detail
2021-01-04 Deleted XREF EC:1.6.5
2021-01-04 Added XREF EC:1.6.5.-
2006-02-09 Deleted XREF EC:1.6.5.-
2006-02-09 Added XREF EC:1.6.5
2001-03-30 Added XREF EC:1.6.5.-
Timestamp Action Category Detail
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