GO:0016656
JSON
monodehydroascorbate reductase (NADH) activity
Molecular Function
Definition (GO:0016656 GONUTS page)
Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
NADH:semidehydroascorbic acid oxidoreductase activity | related |
semidehydroascorbate reductase activity | related |
NADH-semidehydroascorbate oxidoreductase activity | related |
monodehydroascorbate reductase activity | exact |
AFR | related |
MDHA | related |
ascorbic free radical reductase activity | related |
MDAsA reductase (NADPH) | related |
NADH:AFR oxidoreductase activity | related |
NADH:ascorbate radical oxidoreductase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.6.5.4 | |
MetaCyc | 1.6.5.4-RXN | |
RHEA | 14581 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57540 | NAD(1-) |
has_participant | CHEBI | CHEBI:57945 | NADH(2-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:38290 | L-ascorbate |
has_participant | CHEBI | CHEBI:59513 | monodehydro-L-ascorbate(1-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016656 based on ALL annotations
The top 64 of 64 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
monodehydroascorbate reductase (NADH) activity
|
915,205.56 | 100.00 | 213 | 213 |
response to oxygen radical
|
392,230.94 | 1.38 | 3 | 7 |
regulation of biological process involved in symbiotic interaction
|
228,801.39 | 0.46 | 1 | 4 |
stromule
|
3,334.08 | 0.26 | 2 | 549 |
peroxisomal matrix
|
930.67 | 0.10 | 34 | 33,435 |
oxidoreductase activity, acting on NAD(P)H
|
453.67 | 0.05 | 140 | 282,429 |
response to jasmonic acid
|
451.51 | 0.04 | 1 | 2,027 |
cellular response to carbon dioxide
|
411.88 | 0.04 | 2 | 4,444 |
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
|
372.88 | 0.04 | 5 | 12,272 |
positive regulation of phagocytosis
|
379.20 | 0.04 | 2 | 4,827 |
Totals | 1024 | 216497853 |
No co-occurrence statistics for GO:0016656 based on MANUAL annotations
The top 33 of 33 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
monodehydroascorbate reductase (NADH) activity
|
161,474.88 | 100.00 | 8 | 8 |
response to oxygen radical
|
69,203.52 | 25.00 | 3 | 7 |
L-ascorbic acid binding
|
40,368.72 | 14.29 | 2 | 8 |
regulation of biological process involved in symbiotic interaction
|
80,737.44 | 11.11 | 1 | 2 |
cellular oxidant detoxification
|
9,315.86 | 5.26 | 3 | 52 |
carbon utilization
|
6,459.00 | 3.57 | 2 | 50 |
cellular response to carbon dioxide
|
5,294.26 | 2.99 | 2 | 61 |
antioxidant activity
|
3,938.41 | 2.27 | 2 | 82 |
response to symbiotic fungus
|
2,484.23 | 1.39 | 1 | 65 |
carbonate dehydratase activity
|
1,032.89 | 0.63 | 3 | 469 |
Totals | 57 | 471640 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | ascorbic free radical reductase activity |
2020-10-08 | Deleted | SYNONYM | ascorbate free-radical reductase activity |
2020-10-08 | Deleted | SYNONYM | ascorbic free radical reductase activity |
2020-10-08 | Deleted | SYNONYM | semidehydroascorbate reductase activity |
2020-10-08 | Deleted | SYNONYM | AFR-reductase activity |
2020-10-08 | Deleted | SYNONYM | MDAsA reductase (NADPH) |
2020-10-08 | Deleted | SYNONYM | NADH-semidehydroascorbate oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:AFR oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:ascorbate radical oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:monodehydroascorbate oxidoreductase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | monodehydroascorbate reductase (NADH) activity |
2002-05-21 | Updated | TERM | monodehydroascorbate reductase (NADH) |
2002-03-31 | Updated | TERM | monodehydroascorbate reductase (NADH2) |
2002-02-06 | Updated | TERM | monodehydroascorbate reductase (NADH) |
2001-04-03 | Updated | TERM | monodehydroascorbate reductase (NADH) |
2001-03-30 | Added | TERM | monodehydroascorbate reductase (NADH) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | ascorbic free radical reductase activity |
2020-10-08 | Deleted | SYNONYM | ascorbate free-radical reductase activity |
2020-10-08 | Deleted | SYNONYM | ascorbic free radical reductase activity |
2020-10-08 | Deleted | SYNONYM | semidehydroascorbate reductase activity |
2020-10-08 | Deleted | SYNONYM | AFR-reductase activity |
2020-10-08 | Deleted | SYNONYM | MDAsA reductase (NADPH) |
2020-10-08 | Deleted | SYNONYM | NADH-semidehydroascorbate oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:AFR oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:ascorbate radical oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:monodehydroascorbate oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | NADH:semidehydroascorbic acid oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | SDA reductase activity |
2020-10-08 | Deleted | SYNONYM | ascorbate free radical reductase activity |
2020-10-08 | Added | SYNONYM | SDA reductase activity |
2020-10-08 | Added | SYNONYM | AFR-reductase activity |
2020-10-08 | Added | SYNONYM | NADH:AFR oxidoreductase activity |
2020-10-08 | Added | SYNONYM | NADH:semidehydroascorbic acid oxidoreductase activity |
2020-10-08 | Added | SYNONYM | NADH:monodehydroascorbate oxidoreductase activity |
2020-10-08 | Added | SYNONYM | NADH:ascorbate radical oxidoreductase activity |
2020-10-08 | Added | SYNONYM | MDAsA reductase (NADPH) |
2020-10-08 | Added | SYNONYM | semidehydroascorbate reductase activity |
2020-10-08 | Added | SYNONYM | NADH-semidehydroascorbate oxidoreductase activity |
2020-10-08 | Added | SYNONYM | ascorbate free radical reductase activity |
2020-10-08 | Added | SYNONYM | ascorbate free-radical reductase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate. |
2007-11-08 | Added | SYNONYM | ascorbate free-radical reductase activity |
2007-11-08 | Added | SYNONYM | NADH:AFR oxidoreductase activity |
2007-11-08 | Added | SYNONYM | NADH-semidehydroascorbate oxidoreductase activity |
2007-11-08 | Added | SYNONYM | MDHA |
2007-11-08 | Added | SYNONYM | MDAsA reductase (NADPH) |
2007-11-08 | Added | SYNONYM | AFR-reductase activity |
2007-11-08 | Added | SYNONYM | AFR |
2007-11-08 | Deleted | SYNONYM | monodehydroascorbate reductase |
2007-11-08 | Added | SYNONYM | semidehydroascorbate reductase activity |
2007-11-08 | Added | SYNONYM | monodehydroascorbate reductase activity |
2007-11-08 | Added | SYNONYM | ascorbic free radical reductase activity |
2007-11-08 | Added | SYNONYM | ascorbate free radical reductase activity |
2007-11-08 | Added | SYNONYM | SDA reductase activity |
2007-11-08 | Added | SYNONYM | NADH:semidehydroascorbic acid oxidoreductase activity |
2007-11-08 | Added | SYNONYM | NADH:monodehydroascorbate oxidoreductase activity |
2007-11-08 | Added | SYNONYM | NADH:ascorbate radical oxidoreductase activity |
2007-08-09 | Added | SYNONYM | monodehydroascorbate reductase |
2007-08-09 | Deleted | SYNONYM | monodehydroascorbate reductase |
2004-04-19 | Added | SYNONYM | monodehydroascorbate reductase |
2004-04-16 | Deleted | SYNONYM | monodehydroascorbate reductase |
2003-10-27 | Added | SYNONYM | monodehydroascorbate reductase |
2003-08-18 | Deleted | SYNONYM | monodehydroascorbate reductase |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate. |
2001-03-30 | Added | SYNONYM | monodehydroascorbate reductase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016655 (oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:14581 |
2018-07-13 | Deleted | XREF | RHEA:14584 |
2011-09-16 | Added | XREF | RHEA:14584 |
2003-10-27 | Added | XREF | MetaCyc:1.6.5.4-RXN |
2001-03-30 | Added | XREF | EC:1.6.5.4 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link