GO:0016688
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L-ascorbate peroxidase activity
Molecular Function
Definition (GO:0016688 GONUTS page)
Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
L-ascorbate:hydrogen-peroxide oxidoreductase activity | related |
ascorbic acid peroxidase activity | related |
ascorbate peroxidase activity | related |
L-ascorbic acid-specific peroxidase activity | related |
L-ascorbic acid peroxidase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I5Y865 | 10116 | A0A8I5Y865_RAT | GO:0098869 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J8YB21 | 10116 | A0A8J8YB21_RAT | GO:0098869 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.11.1.11 | |
MetaCyc | RXN-12440 | |
RHEA | 22996 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:16240 | hydrogen peroxide |
has_participant | CHEBI | CHEBI:58539 | L-dehydroascorbate |
has_participant | CHEBI | CHEBI:38290 | L-ascorbate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016688 based on ALL annotations
The top 100 of 135 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
L-ascorbate peroxidase activity
|
80,921.04 | 100.00 | 2,409 | 2,409 |
response to reactive oxygen species
|
5,602.78 | 6.84 | 2,036 | 29,406 |
lactoperoxidase activity
|
1,103.16 | 1.26 | 339 | 24,867 |
hydrogen peroxide catabolic process
|
918.06 | 1.13 | 2,206 | 194,445 |
seed germination
|
2,516.68 | 1.08 | 39 | 1,254 |
seed maturation
|
2,975.65 | 1.07 | 36 | 979 |
cellular response to oxidative stress
|
769.64 | 0.95 | 2,313 | 243,191 |
peroxidase activity
|
381.66 | 0.47 | 2,405 | 509,922 |
cellular oxidant detoxification
|
234.12 | 0.29 | 2,409 | 832,643 |
hydrogen peroxide mediated signaling pathway
|
18,391.15 | 0.21 | 5 | 22 |
Totals | 21318 | 101609816 |
No co-occurrence statistics for GO:0016688 based on MANUAL annotations
The top 50 of 50 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
L-ascorbate peroxidase activity
|
161,474.88 | 100.00 | 8 | 8 |
glyoxysomal membrane
|
80,737.44 | 11.11 | 1 | 2 |
p-coumarate 3-hydroxylase activity
|
80,737.44 | 11.11 | 1 | 2 |
prephenate(2-) biosynthetic process
|
53,824.96 | 10.00 | 1 | 3 |
L-ascorbate oxidase activity
|
40,368.72 | 9.09 | 1 | 4 |
iodide peroxidase activity
|
32,294.98 | 8.33 | 1 | 5 |
chloroplast stromal thylakoid
|
14,679.53 | 5.56 | 1 | 11 |
stabilization of membrane potential
|
12,421.15 | 5.00 | 1 | 13 |
phenylpropanoid biosynthetic process
|
4,249.34 | 2.22 | 1 | 38 |
thylakoid lumen
|
2,883.48 | 1.59 | 1 | 56 |
Totals | 75 | 770767 |
Change Log
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- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-08-11 | Deleted | XREF | MetaCyc:L-ASCORBATE-PEROXIDASE-RXN |
2023-08-11 | Added | XREF | MetaCyc:RXN-12440 |
2020-10-08 | Deleted | SYNONYM | ascorbic acid peroxidase activity |
2020-10-08 | Deleted | SYNONYM | ascorbate peroxidase activity |
2020-10-08 | Added | SYNONYM | L-ascorbic acid peroxidase activity |
2020-10-08 | Added | SYNONYM | ascorbate peroxidase activity |
2020-10-08 | Added | SYNONYM | L-ascorbate:hydrogen-peroxide oxidoreductase activity |
2020-10-08 | Added | SYNONYM | ascorbic acid peroxidase activity |
2020-10-08 | Added | SYNONYM | L-ascorbic acid-specific peroxidase activity |
2020-10-08 | Deleted | SYNONYM | L-ascorbic acid-specific peroxidase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | L-ascorbate peroxidase activity |
2002-02-06 | Updated | TERM | L-ascorbate peroxidase |
2001-04-03 | Updated | TERM | L-ascorbate peroxidase |
2001-03-30 | Added | TERM | L-ascorbate peroxidase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | ascorbic acid peroxidase activity |
2020-10-08 | Deleted | SYNONYM | ascorbate peroxidase activity |
2020-10-08 | Added | SYNONYM | L-ascorbic acid peroxidase activity |
2020-10-08 | Added | SYNONYM | ascorbate peroxidase activity |
2020-10-08 | Added | SYNONYM | L-ascorbate:hydrogen-peroxide oxidoreductase activity |
2020-10-08 | Added | SYNONYM | ascorbic acid peroxidase activity |
2020-10-08 | Added | SYNONYM | L-ascorbic acid-specific peroxidase activity |
2020-10-08 | Deleted | SYNONYM | L-ascorbic acid-specific peroxidase activity |
2020-10-08 | Deleted | SYNONYM | L-ascorbic acid peroxidase activity |
2020-10-08 | Deleted | SYNONYM | L-ascorbate:hydrogen-peroxide oxidoreductase activity |
2010-09-03 | Deleted | DEFINITION | Catalysis of the reaction: L-ascorbate + H2O2 = dehydroascorbate + 2 H2O. |
2010-09-03 | Added | DEFINITION | Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: L-ascorbate + H2O2 = dehydroascorbate + 2 H2O. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: L-ascorbate + H2O2 = dehydroascorbate + 2 H2O. |
2007-11-08 | Added | SYNONYM | L-ascorbic acid-specific peroxidase activity |
2007-11-08 | Added | SYNONYM | L-ascorbic acid peroxidase activity |
2007-11-08 | Added | SYNONYM | L-ascorbate:hydrogen-peroxide oxidoreductase activity |
2007-11-08 | Added | SYNONYM | ascorbate peroxidase activity |
2007-09-06 | Added | SYNONYM | ascorbic acid peroxidase activity |
2003-10-23 | Updated | DEFINITION | Catalysis of the reaction: L-ascorbate + H2O2 = dehydroascorbate + 2 H2O. |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0004601 (peroxidase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-08-11 | Deleted | XREF | MetaCyc:L-ASCORBATE-PEROXIDASE-RXN |
2023-08-11 | Added | XREF | MetaCyc:RXN-12440 |
2020-06-22 | Added | XREF | RHEA:22996 |
2003-10-27 | Added | XREF | MetaCyc:L-ASCORBATE-PEROXIDASE-RXN |
2001-03-30 | Added | XREF | EC:1.11.1.11 |
Timestamp | Action | Category | Detail |
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