GO:0016859
JSON
cis-trans isomerase activity
Molecular Function
Definition (GO:0016859 GONUTS page)
Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
Ancestor Chart
Ancestor chart for GO:0016859
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016859
| Child Term | Relationship to GO:0016859 |
|---|---|
|
retinol isomerase activity
|
is_a |
|
linoleate isomerase activity
|
is_a |
|
maleylacetoacetate isomerase activity
|
is_a |
|
9,15,9'-tri-cis-zeta-carotene isomerase activity
|
is_a |
|
beta-carotene isomerase activity
|
is_a |
|
peptidyl-prolyl cis-trans isomerase activity
|
is_a |
|
farnesol 2-isomerase activity
|
is_a |
|
furylfuramide isomerase activity
|
is_a |
|
maleylpyruvate isomerase activity
|
is_a |
|
2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Annotating to catalytic activities using the IPI evidence code | Link |
| Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
| NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
| NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
| NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
| Database | ID | Description |
|---|---|---|
| EC | 5.2.-.- |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016859 based on ALL annotations
The top 97 of 97 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
cis-trans isomerase activity
|
357,680.25 | 100.00 | 554 | 554 |
|
strigolactone biosynthetic process
|
233,828.31 | 57.23 | 455 | 696 |
|
phosphothreonine residue binding
|
162,581.92 | 13.60 | 90 | 198 |
|
phosphoserine residue binding
|
66,101.08 | 9.46 | 90 | 487 |
|
regulation of protein localization to nucleus
|
40,748.38 | 7.18 | 90 | 790 |
|
negative regulation of amyloid-beta formation
|
25,951.56 | 5.32 | 92 | 1,268 |
|
postsynaptic cytosol
|
19,994.55 | 4.34 | 90 | 1,610 |
|
secondary shoot formation
|
38,138.82 | 4.28 | 37 | 347 |
|
negative regulation of SMAD protein signal transduction
|
16,871.71 | 3.79 | 90 | 1,908 |
|
negative regulation of cell motility
|
10,571.83 | 2.56 | 90 | 3,045 |
| Totals | 5331 | 205105622 | ||
No co-occurrence statistics for GO:0016859 based on MANUAL annotations
The top 62 of 62 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
cis-trans isomerase activity
|
88,220.81 | 100.00 | 16 | 16 |
|
phosphothreonine residue binding
|
37,808.92 | 25.00 | 6 | 14 |
|
retinol isomerase activity
|
17,075.00 | 14.63 | 6 | 31 |
|
myelin maintenance
|
15,568.38 | 13.64 | 6 | 34 |
|
regulation of protein localization to nucleus
|
13,572.43 | 12.24 | 6 | 39 |
|
positive regulation of cell growth involved in cardiac muscle cell development
|
11,310.36 | 10.00 | 5 | 39 |
|
negative regulation of amyloid-beta formation
|
8,933.75 | 9.20 | 8 | 79 |
|
regulation protein catabolic process at postsynapse
|
10,025.09 | 9.09 | 5 | 44 |
|
phosphoserine residue binding
|
6,964.80 | 6.98 | 6 | 76 |
|
negative regulation of cell motility
|
5,691.67 | 5.83 | 6 | 93 |
| Totals | 309 | 629084 | ||
Change Log
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- Definition / Synonyms
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-01-04 | Added | XREF | EC:5.2.-.- |
| 2021-01-04 | Deleted | XREF | EC:5.2 |
| 2008-05-13 | Added | DEFINITION | Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. |
| 2008-05-12 | Deleted | DEFINITION | Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. |
| 2008-04-01 | Updated | RELATION | is a GO:0016853 (isomerase activity) |
| 2006-02-09 | Deleted | XREF | EC:5.2.-.- |
| 2006-02-09 | Added | XREF | EC:5.2 |
| 2005-05-19 | Added | DEFINITION | Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. |
| 2003-03-19 | Updated | TERM | cis-trans isomerase activity |
| 2002-02-13 | Updated | TERM | cis-trans isomerase |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2003-03-19 | Updated | TERM | cis-trans isomerase activity |
| 2002-02-13 | Updated | TERM | cis-trans isomerase |
| 2002-02-06 | Updated | TERM | cis-trans-isomerase |
| 2001-04-03 | Updated | TERM | cis-trans-isomerase |
| 2001-03-30 | Added | TERM | cis-trans-isomerase |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-05-13 | Added | DEFINITION | Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. |
| 2008-05-12 | Deleted | DEFINITION | Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. |
| 2005-05-19 | Added | DEFINITION | Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-04-01 | Updated | RELATION | is a GO:0016853 (isomerase activity) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-01-04 | Added | XREF | EC:5.2.-.- |
| 2021-01-04 | Deleted | XREF | EC:5.2 |
| 2006-02-09 | Deleted | XREF | EC:5.2.-.- |
| 2006-02-09 | Added | XREF | EC:5.2 |
| 2001-03-30 | Added | XREF | EC:5.2.-.- |
| Timestamp | Action | Category | Detail |
|---|
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