GO:0016872
JSON
intramolecular lyase activity
Molecular Function
Definition (GO:0016872 GONUTS page)
The catalysis of certain rearrangements of a molecule to break or form a ring.
Ancestor Chart
Ancestor chart for GO:0016872
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016872
Child Term | Relationship to GO:0016872 |
---|---|
geranyl-diphosphate cyclase activity
|
is_a |
dichloromuconate cycloisomerase activity
|
is_a |
ent-copalyl diphosphate synthase activity
|
is_a |
chloromuconate cycloisomerase activity
|
is_a |
inositol-3-phosphate synthase activity
|
is_a |
alpha-pinene-oxide decyclase activity
|
is_a |
kolavenyl diphosphate synthase activity
|
is_a |
syn-copalyl diphosphate synthase activity
|
is_a |
copalyl diphosphate synthase activity
|
is_a |
carboxy-cis,cis-muconate cyclase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q10102 | 284812 | YAQ1_SCHPO | GO:0016872 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:36739946 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.5.1.- | |
InterPro | IPR017825 | Lycopene cyclase domain |
InterPro | IPR023064 | D-ribose pyranase |
InterPro | IPR036298 | Chalcone isomerase superfamily |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016872 based on ALL annotations
The top 100 of 287 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
intramolecular lyase activity
|
8,317.80 | 100.00 | 23,823 | 23,823 |
lycopene beta cyclase activity
|
7,114.34 | 33.12 | 8,359 | 9,773 |
D-ribose pyranase activity
|
4,308.56 | 18.51 | 5,326 | 10,282 |
D-ribose catabolic process
|
1,563.62 | 13.03 | 7,106 | 37,801 |
intramolecular transferase activity
|
1,408.14 | 12.10 | 7,102 | 41,951 |
carotenoid biosynthetic process
|
1,087.03 | 10.52 | 8,359 | 63,962 |
monosaccharide metabolic process
|
819.48 | 8.00 | 7,108 | 72,147 |
monosaccharide binding
|
498.78 | 5.26 | 7,108 | 118,536 |
fatty acid binding
|
489.82 | 3.25 | 1,612 | 27,374 |
chloroplast stroma
|
156.18 | 1.49 | 1,610 | 85,743 |
Totals | 124895 | 109762194 |
No co-occurrence statistics for GO:0016872 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
intramolecular lyase activity
|
235,255.50 | 100.00 | 6 | 6 |
daunorubicin biosynthetic process
|
47,051.10 | 18.18 | 4 | 20 |
doxorubicin metabolic process
|
11,202.64 | 4.65 | 4 | 84 |
antibiotic biosynthetic process
|
10,318.22 | 4.35 | 5 | 114 |
heme binding
|
65.33 | 0.03 | 1 | 3,601 |
mitochondrial inner membrane
|
31.60 | 0.01 | 1 | 7,445 |
mitochondrion
|
4.81 | 0.00 | 1 | 48,955 |
biological_process
|
3.53 | 0.00 | 1 | 66,641 |
Totals | 23 | 126866 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Added | XREF | EC:5.5.1.- |
2021-01-04 | Deleted | XREF | EC:5.5.1 |
2019-12-22 | Deleted | XREF | EC:5.5 |
2019-12-22 | Added | XREF | EC:5.5.1 |
2008-05-13 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2008-05-12 | Deleted | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2008-04-01 | Updated | RELATION | is a GO:0016853 (isomerase activity) |
2006-02-09 | Added | XREF | EC:5.5 |
2006-02-09 | Deleted | XREF | EC:5.5.-.- |
2004-10-28 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | intramolecular lyase activity |
2002-02-06 | Updated | TERM | intramolecular lyase |
2001-04-03 | Updated | TERM | intramolecular lyase |
2001-03-30 | Added | TERM | intramolecular lyase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2008-05-12 | Deleted | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2004-10-28 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016853 (isomerase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Added | XREF | EC:5.5.1.- |
2021-01-04 | Deleted | XREF | EC:5.5.1 |
2019-12-22 | Deleted | XREF | EC:5.5 |
2019-12-22 | Added | XREF | EC:5.5.1 |
2006-02-09 | Added | XREF | EC:5.5 |
2006-02-09 | Deleted | XREF | EC:5.5.-.- |
2001-03-30 | Added | XREF | EC:5.5.-.- |
Timestamp | Action | Category | Detail |
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