GO:0016872
JSON
intramolecular lyase activity
Molecular Function
Definition (GO:0016872 GONUTS page)
The catalysis of certain rearrangements of a molecule to break or form a ring.
Ancestor Chart
Ancestor chart for GO:0016872
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016872
Child Term | Relationship to GO:0016872 |
---|---|
ent-copalyl diphosphate synthase activity
|
is_a |
cycloeucalenol cycloisomerase activity
|
is_a |
halimadienyl-diphosphate synthase activity
|
is_a |
copalyl diphosphate synthase activity
|
is_a |
carboxy-cis,cis-muconate cyclase activity
|
is_a |
syn-copalyl diphosphate synthase activity
|
is_a |
inositol-3-phosphate synthase activity
|
is_a |
chalcone isomerase activity
|
is_a |
tetrahydroxypteridine cycloisomerase activity
|
is_a |
chloromuconate cycloisomerase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q10102 | 284812 | YAQ1_SCHPO | GO:0016872 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:36739946 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.5.1.- | |
InterPro | IPR017825 | Lycopene cyclase domain |
InterPro | IPR023064 | D-ribose pyranase |
InterPro | IPR036298 | Chalcone isomerase superfamily |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016872 based on ALL annotations
The top 100 of 292 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
intramolecular lyase activity
|
8,385.19 | 100.00 | 23,248 | 23,248 |
lycopene beta cyclase activity
|
7,169.44 | 33.72 | 8,315 | 9,725 |
D-ribose pyranase activity
|
4,356.38 | 19.20 | 5,426 | 10,444 |
D-ribose catabolic process
|
1,558.92 | 12.88 | 6,863 | 36,915 |
intramolecular transferase activity
|
1,419.39 | 12.05 | 6,860 | 40,526 |
carotenoid biosynthetic process
|
1,135.27 | 10.89 | 8,315 | 61,415 |
monosaccharide metabolic process
|
816.73 | 7.90 | 6,864 | 70,471 |
monosaccharide binding
|
494.87 | 5.17 | 6,864 | 116,305 |
fatty acid binding
|
459.07 | 3.00 | 1,445 | 26,394 |
geranylgeranyl-diphosphate geranylgeranyltransferase activity
|
610.07 | 1.98 | 615 | 8,453 |
Totals | 122535 | 107086942 |
No co-occurrence statistics for GO:0016872 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
intramolecular lyase activity
|
215,299.84 | 100.00 | 6 | 6 |
daunorubicin biosynthetic process
|
43,059.97 | 18.18 | 4 | 20 |
doxorubicin metabolic process
|
13,048.48 | 5.88 | 4 | 66 |
antibiotic biosynthetic process
|
9,786.36 | 4.50 | 5 | 110 |
heme binding
|
63.55 | 0.03 | 1 | 3,388 |
mitochondrial inner membrane
|
30.78 | 0.01 | 1 | 6,995 |
mitochondrion
|
4.70 | 0.00 | 1 | 45,791 |
biological_process
|
3.24 | 0.00 | 1 | 66,439 |
Totals | 23 | 122815 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Added | XREF | EC:5.5.1.- |
2021-01-04 | Deleted | XREF | EC:5.5.1 |
2019-12-22 | Added | XREF | EC:5.5.1 |
2019-12-22 | Deleted | XREF | EC:5.5 |
2008-05-13 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2008-05-12 | Deleted | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2008-04-01 | Updated | RELATION | is a GO:0016853 (isomerase activity) |
2006-02-09 | Deleted | XREF | EC:5.5.-.- |
2006-02-09 | Added | XREF | EC:5.5 |
2004-10-28 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | intramolecular lyase activity |
2002-02-06 | Updated | TERM | intramolecular lyase |
2001-04-03 | Updated | TERM | intramolecular lyase |
2001-03-30 | Added | TERM | intramolecular lyase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2008-05-12 | Deleted | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
2004-10-28 | Added | DEFINITION | The catalysis of certain rearrangements of a molecule to break or form a ring. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016853 (isomerase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-01-04 | Added | XREF | EC:5.5.1.- |
2021-01-04 | Deleted | XREF | EC:5.5.1 |
2019-12-22 | Added | XREF | EC:5.5.1 |
2019-12-22 | Deleted | XREF | EC:5.5 |
2006-02-09 | Deleted | XREF | EC:5.5.-.- |
2006-02-09 | Added | XREF | EC:5.5 |
2001-03-30 | Added | XREF | EC:5.5.-.- |
Timestamp | Action | Category | Detail |
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