This term is obsolete.

GO:0016872 JSON

intramolecular lyase activity

Molecular Function

Definition (GO:0016872 GONUTS page)

The catalysis of certain rearrangements of a molecule to break or form a ring.

57,462 annotations

Ancestor Chart

Ancestor chart for GO:0016872
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016872

Child Term Relationship to
GO:0016872
ent-copalyl diphosphate synthase activity
is_a
cycloeucalenol cycloisomerase activity
is_a
halimadienyl-diphosphate synthase activity
is_a
copalyl diphosphate synthase activity
is_a
carboxy-cis,cis-muconate cyclase activity
is_a
syn-copalyl diphosphate synthase activity
is_a
inositol-3-phosphate synthase activity
is_a
chalcone isomerase activity
is_a
tetrahydroxypteridine cycloisomerase activity
is_a
chloromuconate cycloisomerase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q10102 284812 YAQ1_SCHPO GO:0016872 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:36739946
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 5.5.1.-
InterPro IPR017825 Lycopene cyclase domain
InterPro IPR023064 D-ribose pyranase
InterPro IPR036298 Chalcone isomerase superfamily

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016872 based on ALL annotations
The top 100 of 292 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intramolecular lyase activity
8,385.19 100.00 23,248 23,248
lycopene beta cyclase activity
7,169.44 33.72 8,315 9,725
D-ribose pyranase activity
4,356.38 19.20 5,426 10,444
D-ribose catabolic process
1,558.92 12.88 6,863 36,915
intramolecular transferase activity
1,419.39 12.05 6,860 40,526
carotenoid biosynthetic process
1,135.27 10.89 8,315 61,415
monosaccharide metabolic process
816.73 7.90 6,864 70,471
monosaccharide binding
494.87 5.17 6,864 116,305
fatty acid binding
459.07 3.00 1,445 26,394
geranylgeranyl-diphosphate geranylgeranyltransferase activity
610.07 1.98 615 8,453
Totals 122535 107086942
No co-occurrence statistics for GO:0016872 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intramolecular lyase activity
215,299.84 100.00 6 6
daunorubicin biosynthetic process
43,059.97 18.18 4 20
doxorubicin metabolic process
13,048.48 5.88 4 66
antibiotic biosynthetic process
9,786.36 4.50 5 110
heme binding
63.55 0.03 1 3,388
mitochondrial inner membrane
30.78 0.01 1 6,995
mitochondrion
4.70 0.00 1 45,791
biological_process
3.24 0.00 1 66,439
Totals 23 122815

Change Log

Timestamp Action Category Detail
2021-01-04 Added XREF EC:5.5.1.-
2021-01-04 Deleted XREF EC:5.5.1
2019-12-22 Added XREF EC:5.5.1
2019-12-22 Deleted XREF EC:5.5
2008-05-13 Added DEFINITION The catalysis of certain rearrangements of a molecule to break or form a ring.
2008-05-12 Deleted DEFINITION The catalysis of certain rearrangements of a molecule to break or form a ring.
2008-04-01 Updated RELATION is a GO:0016853 (isomerase activity)
2006-02-09 Deleted XREF EC:5.5.-.-
2006-02-09 Added XREF EC:5.5
2004-10-28 Added DEFINITION The catalysis of certain rearrangements of a molecule to break or form a ring.
Timestamp Action Category Detail
2003-03-19 Updated TERM intramolecular lyase activity
2002-02-06 Updated TERM intramolecular lyase
2001-04-03 Updated TERM intramolecular lyase
2001-03-30 Added TERM intramolecular lyase
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The catalysis of certain rearrangements of a molecule to break or form a ring.
2008-05-12 Deleted DEFINITION The catalysis of certain rearrangements of a molecule to break or form a ring.
2004-10-28 Added DEFINITION The catalysis of certain rearrangements of a molecule to break or form a ring.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016853 (isomerase activity)
Timestamp Action Category Detail
2021-01-04 Added XREF EC:5.5.1.-
2021-01-04 Deleted XREF EC:5.5.1
2019-12-22 Added XREF EC:5.5.1
2019-12-22 Deleted XREF EC:5.5
2006-02-09 Deleted XREF EC:5.5.-.-
2006-02-09 Added XREF EC:5.5
2001-03-30 Added XREF EC:5.5.-.-
Timestamp Action Category Detail
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