GO:0016925
JSON
protein sumoylation
Biological Process
Definition (GO:0016925 GONUTS page)
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. PMID:11265250
Secondary IDs
GO:0006485, GO:0016927, GO:0019947, GO:0019951
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Smt3p-protein conjugation | related |
Smt3-protein conjugation | related |
sumoylation | exact |
small ubiquitin-related protein 1 conjugation | exact |
protein sumolation | exact |
SUMO-protein conjugation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0016925
Child Term | Relationship to GO:0016925 |
---|---|
positive regulation of protein sumoylation
|
positively_regulates |
SUMO ligase complex
|
capable_of_part_of |
regulation of protein sumoylation
|
regulates |
protein autosumoylation
|
is_a |
negative regulation of protein sumoylation
|
negatively_regulates |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR030661 | SUMO-activating enzyme subunit Uba2 |
InterPro | IPR033950 | Sumo domain |
Wikipedia | SUMO_protein |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0019940 | obsolete SUMO-dependent protein catabolic process | consider GO:0016925 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0016925 based on ALL annotations
The top 100 of 1,250 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein sumoylation
|
4,860.59 | 100.00 | 40,106 | 40,106 |
SUMO ligase activity
|
4,848.40 | 53.48 | 21,478 | 21,532 |
SUMO activating enzyme activity
|
4,859.87 | 33.56 | 13,462 | 13,464 |
SUMO activating enzyme complex
|
4,860.59 | 33.48 | 13,427 | 13,427 |
SUMO transferase activity
|
4,687.65 | 29.81 | 12,089 | 12,535 |
regulation of macromolecule metabolic process
|
813.68 | 9.84 | 7,725 | 46,146 |
ubiquitin-like modifier activating enzyme activity
|
432.70 | 7.09 | 10,334 | 116,083 |
protein modification by small protein conjugation
|
966.95 | 6.32 | 3,403 | 17,106 |
Smc5-Smc6 complex
|
757.13 | 6.22 | 3,762 | 24,151 |
nuclear receptor coactivator activity
|
686.30 | 5.88 | 3,669 | 25,985 |
Totals | 238441 | 14308372 |
No co-occurrence statistics for GO:0016925 based on MANUAL annotations
The top 100 of 790 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protein sumoylation
|
836.12 | 100.00 | 1,545 | 1,545 |
SUMO ligase activity
|
827.38 | 36.62 | 568 | 574 |
ubiquitin-like protein ligase binding
|
566.35 | 22.02 | 380 | 561 |
SUMO activating enzyme activity
|
828.91 | 14.87 | 230 | 232 |
SUMO activating enzyme complex
|
836.12 | 14.82 | 229 | 229 |
protein tag activity
|
172.99 | 12.73 | 384 | 1,856 |
SUMO conjugating enzyme activity
|
836.12 | 11.72 | 181 | 181 |
Smc5-Smc6 complex
|
168.06 | 5.97 | 121 | 602 |
SUMO transferase activity
|
378.35 | 4.93 | 81 | 179 |
transcription factor binding
|
361.56 | 4.85 | 80 | 185 |
Totals | 6756 | 344246 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-08-30 | Added | SECONDARY | GO:0019951 (Smt3-protein conjugation) |
2021-08-30 | Added | SYNONYM | Smt3-protein conjugation |
2021-08-30 | Added | SYNONYM | Smt3p-protein conjugation |
2020-02-28 | Deleted | XREF | MIPS_funcat:14.07.07 |
2019-05-04 | Added | XREF | MIPS_funcat:14.07.07 |
2018-12-18 | Deleted | DEFINITION | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2018-12-18 | Added | DEFINITION | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2015-01-30 | Added | RELATION | is a GO:0018205 (peptidyl-lysine modification) |
2010-12-01 | Deleted | DEFINITION | The process by which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2010-12-01 | Added | DEFINITION | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | protein sumoylation |
2001-04-03 | Updated | TERM | protein sumoylation |
2001-03-30 | Added | TERM | protein sumoylation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-08-30 | Added | SYNONYM | Smt3-protein conjugation |
2021-08-30 | Added | SYNONYM | Smt3p-protein conjugation |
2018-12-18 | Deleted | DEFINITION | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2018-12-18 | Added | DEFINITION | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2010-12-01 | Deleted | DEFINITION | The process by which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2010-12-01 | Added | DEFINITION | The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2008-05-13 | Added | DEFINITION | The process by which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2008-05-12 | Deleted | DEFINITION | The process by which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2007-09-10 | Deleted | SYNONYM | SUMO-dependent protein catabolic process |
2007-09-10 | Deleted | SYNONYM | SUMO-dependent protein catabolism |
2007-08-09 | Deleted | SYNONYM | SUMO-dependent protein catabolic process |
2007-08-09 | Deleted | SYNONYM | sumoylation |
2007-08-09 | Deleted | SYNONYM | small ubiquitin-related protein 1 conjugation |
2007-08-09 | Deleted | SYNONYM | protein sumolation |
2007-08-09 | Deleted | SYNONYM | SUMO-protein conjugation |
2007-08-09 | Deleted | SYNONYM | SUMO-dependent protein catabolism |
2007-08-09 | Added | SYNONYM | sumoylation |
2007-08-09 | Added | SYNONYM | small ubiquitin-related protein 1 conjugation |
2007-08-09 | Added | SYNONYM | protein sumolation |
2007-08-09 | Added | SYNONYM | SUMO-protein conjugation |
2007-08-09 | Added | SYNONYM | SUMO-dependent protein catabolism |
2007-08-09 | Added | SYNONYM | SUMO-dependent protein catabolic process |
2007-01-15 | Added | SYNONYM | SUMO-dependent protein catabolic process |
2005-08-10 | Added | SYNONYM | SUMO-dependent protein catabolism |
2004-04-19 | Added | SYNONYM | small ubiquitin-related protein 1 conjugation |
2004-04-19 | Added | SYNONYM | SUMO-protein conjugation |
2004-04-19 | Added | SYNONYM | protein sumolation |
2004-04-19 | Added | SYNONYM | sumoylation |
2004-04-16 | Deleted | SYNONYM | SUMO-protein conjugation |
2004-04-16 | Deleted | SYNONYM | sumoylation |
2004-04-16 | Deleted | SYNONYM | protein sumolation |
2004-04-16 | Deleted | SYNONYM | small ubiquitin-related protein 1 conjugation |
2003-08-18 | Added | SYNONYM | protein sumolation |
2003-05-08 | Added | SYNONYM | sumoylation |
2003-05-08 | Added | SYNONYM | SUMO-protein conjugation |
2003-05-08 | Updated | DEFINITION | The process by which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. |
2003-04-24 | Updated | DEFINITION | The posttranslational modification of a protein by a member of the SUMO protein family; SUMO proteins (small ubiquitin-related modifiers, otherwise known as sentrin) are present in all eukaryotic kingdoms and are highly conserved from yeast to humans. They seem to play a role in the nuclear import of protein and eventually serve as address tags for transport to PML bodies. |
2002-11-27 | Updated | DEFINITION | Post-translational modification of a protein by a member of the SUMO protein family; SUMO proteins (small ubuquitin-related modifiers, otherwise known as sentrin) are present in all eukaryotic kingdoms and are highly conserved from yeast to humans. They seem to play a role in the nuclear import of protein and eventually serve as address tags for transport to PML bodies. |
2001-08-06 | Added | DEFINITION | Post-translational modification of a protein by a member of the SUMO protein family; SUMO proteins (small ubuquitin-related modifiers, aka sentrin) are present in all eukaryotic kingdoms and are highly conserved from yeast to humans. They seem to play a role in the nuclear import of protein and eventually serve as address tags for transport to PML bodies. |
2001-03-30 | Added | SYNONYM | small ubiquitin-related protein 1 conjugation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-01-30 | Added | RELATION | is a GO:0018205 (peptidyl-lysine modification) |
2010-10-17 | Deleted | RELATION | is a GO:0006464 (cellular protein modification process) |
2010-10-15 | Added | RELATION | is a GO:0006464 (cellular protein modification process) |
2010-10-15 | Deleted | RELATION | is a GO:0043687 (post-translational protein modification) |
2008-08-04 | Added | RELATION | is a GO:0043687 (post-translational protein modification) |
2008-04-01 | Updated | RELATION | is a GO:0032446 (protein modification by small protein conjugation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:14.07.07 |
2019-05-04 | Added | XREF | MIPS_funcat:14.07.07 |
2009-03-29 | Added | XREF | Wikipedia:SUMO_protein |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-08-30 | Added | SECONDARY | GO:0019951 (Smt3-protein conjugation) |
2003-05-08 | Added | SECONDARY | GO:0016927 (sumoylation) |
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