This term is obsolete.

GO:0016934 JSON

extracellularly glycine-gated chloride channel activity

Molecular Function

Definition (GO:0016934 GONUTS page)

Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.

Secondary IDs

GO:0004891

3,029 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
glycine receptor broad
glycine-inhibited chloride channel activity related
extracellular-glycine-gated chloride channel activity exact

Ancestor Chart

Ancestor chart for GO:0016934
Chart options
Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0016934 extracellularly glycine-gated chloride channel activity Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2K0W3 10116 A0A0G2K0W3_RAT GO:0005254 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZKP5 10116 A0A8I5ZKP5_RAT GO:0005254 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZLE9 10116 A0A8I5ZLE9_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZST4 10116 A0A8I5ZST4_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AI08 10116 A0A8I6AI08_RAT GO:0015267 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0PK00 9606 T120B_HUMAN GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6HVQ8 10116 A6HVQ8_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6J168 10116 A6J168_RAT GO:0005216 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6J4P5 10116 A6J4P5_RAT GO:0015267 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K1R8 10116 A6K1R8_RAT GO:0005254 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR008060 Glycine receptor beta
InterPro IPR008128 Glycine receptor alpha1
InterPro IPR008129 Glycine receptor alpha2
InterPro IPR008130 Glycine receptor alpha3
Reactome R-HSA-975389

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0016934 based on ALL annotations
The top 100 of 105 co-occurring terms
Co-occurring Term PR S% #Together #Compared
extracellularly glycine-gated chloride channel activity
65,196.92 100.00 2,990 2,990
transmitter-gated monoatomic ion channel activity
30,324.53 36.34 1,867 4,014
glycinergic synapse
45,883.87 11.85 373 530
excitatory postsynaptic potential
4,971.66 7.63 2,990 39,210
glycine-gated chloride channel complex
65,196.92 7.22 216 216
glycine-gated chloride ion channel activity
64,269.94 6.95 208 211
synaptic transmission, glycinergic
37,874.51 6.41 201 346
cellular response to ethanol
16,887.35 5.64 201 776
righting reflex
19,111.16 5.56 192 655
startle response
8,361.13 5.36 252 1,965
Totals 45252 112615274
No co-occurrence statistics for GO:0016934 based on MANUAL annotations
The top 77 of 77 co-occurring terms
Co-occurring Term PR S% #Together #Compared
extracellularly glycine-gated chloride channel activity
46,135.68 100.00 28 28
glycinergic synapse
18,742.62 27.66 13 32
glycine-gated chloride channel complex
41,009.49 27.59 8 9
extracellularly glycine-gated ion channel activity
25,951.32 25.71 9 16
synaptic transmission, glycinergic
7,583.95 13.48 12 73
negative regulation of transmission of nerve impulse
23,067.84 12.50 4 8
taurine binding
23,067.84 12.50 4 8
glycine-gated chloride ion channel activity
23,067.84 12.50 4 8
startle response
4,092.68 7.80 11 124
cellular response to ethanol
4,342.18 7.62 8 85
Totals 477 347206

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2019-04-01 Added XREF Reactome:R-HSA-975389
2019-04-01 Deleted XREF reactome:R-HSA-975389
2018-12-11 Added XREF reactome:R-HSA-975389
2017-11-01 Updated TERM extracellularly glycine-gated chloride channel activity
2017-11-01 Added SYNONYM extracellular-glycine-gated chloride channel activity
2017-11-01 Added DEFINITION Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2017-11-01 Deleted DEFINITION Enables the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2016-11-28 Added RELATION is a GO:0005254 (chloride channel activity)
2016-11-28 Deleted RELATION is a GO:0061797 (pH-gated chloride channel activity)
Timestamp Action Category Detail
2017-11-01 Updated TERM extracellularly glycine-gated chloride channel activity
2010-06-09 Updated TERM extracellular-glycine-gated chloride channel activity
2010-06-08 Updated TERM extracellular-glycine-gated chloride channel activity
2007-07-11 Updated TERM extracellular-glycine-gated chloride channel activity
2003-03-19 Updated TERM glycine-gated chloride channel activity
2002-02-06 Updated TERM glycine-gated chloride channel
2001-04-03 Updated TERM glycine-gated chloride channel
2001-03-30 Added TERM glycine-gated chloride channel
Timestamp Action Category Detail
2017-11-01 Added SYNONYM extracellular-glycine-gated chloride channel activity
2017-11-01 Added DEFINITION Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
2017-11-01 Deleted DEFINITION Enables the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2015-05-11 Added DEFINITION Enables the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2015-05-11 Deleted DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2009-10-30 Added SYNONYM glycine-inhibited chloride channel activity
2008-05-13 Added DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2008-05-12 Deleted DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2008-03-11 Updated DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2007-08-09 Added SYNONYM glycine receptor
2007-08-09 Deleted SYNONYM glycine receptor
2007-07-27 Added DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
2004-04-19 Added SYNONYM glycine receptor
2004-04-16 Deleted SYNONYM glycine receptor
2001-03-30 Added SYNONYM glycine receptor
Timestamp Action Category Detail
2016-11-28 Added RELATION is a GO:0005254 (chloride channel activity)
2016-11-28 Deleted RELATION is a GO:0061797 (pH-gated chloride channel activity)
2016-11-28 Added RELATION is a GO:0099095 (ligand-gated monoatomic anion channel activity)
2016-10-08 Added RELATION is a GO:0061797 (pH-gated chloride channel activity)
2016-10-08 Deleted RELATION is a GO:0005254 (chloride channel activity)
2009-10-30 Added RELATION is a GO:0005237 (inhibitory extracellular ligand-gated monoatomic ion channel activity)
2008-04-01 Updated RELATION is a GO:0005254 (chloride channel activity)
2008-04-01 Updated RELATION is a GO:0016933 (extracellularly glycine-gated ion channel activity)
Timestamp Action Category Detail
2019-04-01 Added XREF Reactome:R-HSA-975389
2019-04-01 Deleted XREF reactome:R-HSA-975389
2018-12-11 Added XREF reactome:R-HSA-975389
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2009-10-30 Added SECONDARY GO:0004891 (glycine-inhibited chloride channel activity)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.