This term is obsolete.

GO:0018578 JSON

protocatechuate 3,4-dioxygenase activity

Molecular Function

Definition (GO:0018578 GONUTS page)

Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.

15,070 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
protocatechuic 3,4-oxygenase activity related
protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) related
protocatechuic acid oxidase activity related
protocatechuic 3,4-dioxygenase activity related
protocatechuate oxygenase activity broad

Ancestor Chart

Ancestor chart for GO:0018578
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 5270 BI1_MYCMD GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein D3ZKX9 10116 LOXE3_RAT GO:0016702 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 1.13.11.3
InterPro IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit
InterPro IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit
InterPro IPR039387 Protocatechuate 3,4-dioxygenase
MetaCyc PROTOCATECHUATE-34-DIOXYGENASE-RXN
RHEA 10084
UM-BBD_reactionID r0143

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57496 3-carboxy-cis,cis-muconate(3-)
has_participant CHEBI CHEBI:15379 dioxygen
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:36241 3,4-dihydroxybenzoate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0018578 based on ALL annotations
The top 57 of 57 co-occurring terms
Co-occurring Term PR S% #Together #Compared
protocatechuate 3,4-dioxygenase activity
13,148.96 100.00 15,070 15,070
3,4-dihydroxybenzoate catabolic process
3,803.71 21.44 6,829 23,607
ferric iron binding
1,392.20 10.57 14,874 140,481
catabolic process
343.93 2.54 7,045 269,342
dioxygenase activity
286.05 2.18 14,997 689,371
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
12.59 0.09 129 134,697
indoleacetylglucose-inositol O-acyltransferase activity
13,148.96 0.03 5 5
catechol 1,2-dioxygenase activity
9.06 0.03 9 13,067
catechol-containing compound metabolic process
7.59 0.02 6 10,398
beta-ketoadipate pathway
5.41 0.02 7 17,005
Totals 59317 218533471
No co-occurrence statistics for GO:0018578 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Totals 0 0

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Added SYNONYM protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Deleted SYNONYM protocatechuic 3,4-oxygenase activity
2020-10-08 Deleted SYNONYM protocatechuic 3,4-dioxygenase activity
2020-10-08 Deleted SYNONYM protocatechuic acid oxidase activity
2020-10-08 Added SYNONYM protocatechuic acid oxidase activity
2020-10-08 Added SYNONYM protocatechuic 3,4-dioxygenase activity
2020-10-08 Added SYNONYM protocatechuic 3,4-oxygenase activity
2018-07-13 Added XREF RHEA:10084
2018-07-13 Deleted XREF RHEA:10087
Timestamp Action Category Detail
2003-03-19 Updated TERM protocatechuate 3,4-dioxygenase activity
2001-10-01 Added TERM protocatechuate 3,4-dioxygenase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Added SYNONYM protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Deleted SYNONYM protocatechuic 3,4-oxygenase activity
2020-10-08 Deleted SYNONYM protocatechuic 3,4-dioxygenase activity
2020-10-08 Deleted SYNONYM protocatechuic acid oxidase activity
2020-10-08 Added SYNONYM protocatechuic acid oxidase activity
2020-10-08 Added SYNONYM protocatechuic 3,4-dioxygenase activity
2020-10-08 Added SYNONYM protocatechuic 3,4-oxygenase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.
2007-11-08 Added SYNONYM protocatechuic acid oxidase activity
2007-11-08 Added SYNONYM protocatechuic 3,4-oxygenase activity
2007-11-08 Added SYNONYM protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)
2007-11-08 Added SYNONYM protocatechuic 3,4-dioxygenase activity
2007-09-06 Added SYNONYM protocatechuate oxygenase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:10084
2018-07-13 Deleted XREF RHEA:10087
2011-09-16 Added XREF RHEA:10087
2011-05-03 Deleted XREF UM-BBD_enzymeID:e0114
2011-05-03 Added XREF UM-BBD_reactionID:r0143
2009-05-21 Added XREF MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN
2009-05-21 Deleted XREF MetaCyc:PROTOCATECHUATE-3,4-DIOXYGENASE-RXN
2003-10-27 Added XREF UM-BBD_enzymeID:e0114
2003-10-27 Added XREF MetaCyc:PROTOCATECHUATE-3,4-DIOXYGENASE-RXN
2001-10-01 Added XREF EC:1.13.11.3
Timestamp Action Category Detail
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