GO:0018578
JSON
protocatechuate 3,4-dioxygenase activity
Molecular Function
Definition (GO:0018578 GONUTS page)
Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
protocatechuic 3,4-oxygenase activity | related |
protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) | related |
protocatechuic acid oxidase activity | related |
protocatechuic 3,4-dioxygenase activity | related |
protocatechuate oxygenase activity | broad |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | D3ZKX9 | 10116 | LOXE3_RAT | GO:0016702 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.13.11.3 | |
InterPro | IPR012785 | Protocatechuate 3,4-dioxygenase, beta subunit |
InterPro | IPR012786 | Protocatechuate 3,4-dioxygenase, alpha subunit |
InterPro | IPR039387 | Protocatechuate 3,4-dioxygenase |
MetaCyc | PROTOCATECHUATE-34-DIOXYGENASE-RXN | |
RHEA | 10084 | |
UM-BBD_reactionID | r0143 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57496 | 3-carboxy-cis,cis-muconate(3-) |
has_participant | CHEBI | CHEBI:15379 | dioxygen |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:36241 | 3,4-dihydroxybenzoate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0018578 based on ALL annotations
The top 57 of 57 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
protocatechuate 3,4-dioxygenase activity
|
13,148.96 | 100.00 | 15,070 | 15,070 |
3,4-dihydroxybenzoate catabolic process
|
3,803.71 | 21.44 | 6,829 | 23,607 |
ferric iron binding
|
1,392.20 | 10.57 | 14,874 | 140,481 |
catabolic process
|
343.93 | 2.54 | 7,045 | 269,342 |
dioxygenase activity
|
286.05 | 2.18 | 14,997 | 689,371 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
12.59 | 0.09 | 129 | 134,697 |
indoleacetylglucose-inositol O-acyltransferase activity
|
13,148.96 | 0.03 | 5 | 5 |
catechol 1,2-dioxygenase activity
|
9.06 | 0.03 | 9 | 13,067 |
catechol-containing compound metabolic process
|
7.59 | 0.02 | 6 | 10,398 |
beta-ketoadipate pathway
|
5.41 | 0.02 | 7 | 17,005 |
Totals | 59317 | 218533471 |
No co-occurrence statistics for GO:0018578 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Totals | 0 | 0 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Added | SYNONYM | protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Deleted | SYNONYM | protocatechuic 3,4-oxygenase activity |
2020-10-08 | Deleted | SYNONYM | protocatechuic 3,4-dioxygenase activity |
2020-10-08 | Deleted | SYNONYM | protocatechuic acid oxidase activity |
2020-10-08 | Added | SYNONYM | protocatechuic acid oxidase activity |
2020-10-08 | Added | SYNONYM | protocatechuic 3,4-dioxygenase activity |
2020-10-08 | Added | SYNONYM | protocatechuic 3,4-oxygenase activity |
2018-07-13 | Added | XREF | RHEA:10084 |
2018-07-13 | Deleted | XREF | RHEA:10087 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | protocatechuate 3,4-dioxygenase activity |
2001-10-01 | Added | TERM | protocatechuate 3,4-dioxygenase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Added | SYNONYM | protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Deleted | SYNONYM | protocatechuic 3,4-oxygenase activity |
2020-10-08 | Deleted | SYNONYM | protocatechuic 3,4-dioxygenase activity |
2020-10-08 | Deleted | SYNONYM | protocatechuic acid oxidase activity |
2020-10-08 | Added | SYNONYM | protocatechuic acid oxidase activity |
2020-10-08 | Added | SYNONYM | protocatechuic 3,4-dioxygenase activity |
2020-10-08 | Added | SYNONYM | protocatechuic 3,4-oxygenase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate. |
2007-11-08 | Added | SYNONYM | protocatechuic acid oxidase activity |
2007-11-08 | Added | SYNONYM | protocatechuic 3,4-oxygenase activity |
2007-11-08 | Added | SYNONYM | protocatechuate:oxygen 3,4-oxidoreductase (decyclizing) |
2007-11-08 | Added | SYNONYM | protocatechuic 3,4-dioxygenase activity |
2007-09-06 | Added | SYNONYM | protocatechuate oxygenase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:10084 |
2018-07-13 | Deleted | XREF | RHEA:10087 |
2011-09-16 | Added | XREF | RHEA:10087 |
2011-05-03 | Deleted | XREF | UM-BBD_enzymeID:e0114 |
2011-05-03 | Added | XREF | UM-BBD_reactionID:r0143 |
2009-05-21 | Added | XREF | MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN |
2009-05-21 | Deleted | XREF | MetaCyc:PROTOCATECHUATE-3,4-DIOXYGENASE-RXN |
2003-10-27 | Added | XREF | UM-BBD_enzymeID:e0114 |
2003-10-27 | Added | XREF | MetaCyc:PROTOCATECHUATE-3,4-DIOXYGENASE-RXN |
2001-10-01 | Added | XREF | EC:1.13.11.3 |
Timestamp | Action | Category | Detail |
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