This term is obsolete.

GO:0019049 JSON

virus-mediated perturbation of host defense response

Biological Process

Definition (GO:0019049 GONUTS page)

A process in which a virus interferes with the ability of the host to mount a defense in response to its presence. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.

Secondary IDs

GO:0019052, GO:0019053, GO:0030683, GO:0050690

379,851 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
evasion of host defenses by virus narrow
mitigation of host antiviral defense response narrow
regulation of defense response to virus by virus exact
viral regulation of antiviral response exact
viral host defence evasion narrow
viral host defense evasion narrow
perturbation of host defense response by virus exact
regulation by virus of antiviral response narrow
mitigation of host defenses by virus exact

Ancestor Chart

Ancestor chart for GO:0019049
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019049

Child Term Relationship to
GO:0019049
suppression by virus of host tetherin activity
is_a
perturbation by virus of host immune response
is_a
evasion by virus of host dendritic cell activity
is_a
evasion by virus of host natural killer cell activity
is_a

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
Viral Processes Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0019049 virus-mediated perturbation of host defense response Never in Taxon 33090 Viridiplantae
GO:0019049 virus-mediated perturbation of host defense response Never in Taxon 4895 Schizosaccharomyces
GO:0019049 virus-mediated perturbation of host defense response Never in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
InterPro IPR002532 Hantavirus glycoprotein Gc, N-terminal domain
InterPro IPR002534 Hantavirus glycoprotein Gn, head
InterPro IPR002608 Paramyxovirus non-structural protein C
InterPro IPR004985 Adenovirus E3-15
InterPro IPR006965 Adenovirus Gp19K
InterPro IPR008026 Herpesvirus ICP47
InterPro IPR009174 Orthopoxvirus, Protein K7
InterPro IPR009353 Orthopoxvirus, Protein N1
InterPro IPR011172 Poxvirus, TNF-alpha receptor-II
InterPro IPR012536 Cytomegalovirus US glycoprotein

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0019049 based on ALL annotations
The top 100 of 804 co-occurring terms
Co-occurring Term PR S% #Together #Compared
virus-mediated perturbation of host defense response
533.77 100.00 365,209 365,209
symbiont-mediated suppression of host type I interferon-mediated signaling pathway
471.01 27.90 105,821 119,923
symbiont-mediated suppression of host innate immune response
466.26 26.78 101,742 116,475
fusion of virus membrane with host endosome membrane
182.65 21.12 129,822 379,382
symbiont-mediated suppression of host PKR/eIFalpha signaling
533.43 18.66 68,174 68,218
viral protein processing
489.04 18.66 69,340 75,683
protein serine/threonine kinase inhibitor activity
515.52 18.54 68,175 70,589
clathrin-dependent endocytosis of virus by host cell
193.53 17.91 95,471 263,313
host cell endosome membrane
374.22 17.20 67,802 96,711
host cell endosome
346.34 17.02 68,467 105,521
Totals 4553381 34215482
No co-occurrence statistics for GO:0019049 based on MANUAL annotations
The top 100 of 136 co-occurring terms
Co-occurring Term PR S% #Together #Compared
virus-mediated perturbation of host defense response
430,599.70 100.00 3 3
negative regulation of protein maturation
430,599.66 33.33 1 1
regulation of tRNA methylation
215,299.83 25.00 1 2
positive regulation of endodeoxyribonuclease activity
86,119.94 14.29 1 5
negative regulation of protein localization to lysosome
71,766.62 12.50 1 6
maintenance of protein location in mitochondrion
43,059.97 8.33 1 10
positive regulation of protein localization to endoplasmic reticulum
39,145.43 7.69 1 11
negative regulation of long-chain fatty acid import across plasma membrane
39,145.43 7.69 1 11
symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
28,706.65 5.88 1 15
negative regulation of leukocyte cell-cell adhesion
26,912.48 5.56 1 16
Totals 102 24241

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_virus 23

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:7742 (Vertebrata)
2024-06-07 Added SUBSET goslim_virus
2023-10-10 Deleted DEFINITION A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-10-10 Added DEFINITION A process in which a virus interferes with the ability of the host to mount a defense in response to its presence. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-10-10 Deleted SYNONYM regulation by virus of antiviral response
2023-10-10 Added SYNONYM mitigation of host antiviral defense response
2023-10-10 Updated TERM virus-mediated perturbation of host defense response
2023-10-10 Added SYNONYM perturbation of host defense response by virus
Timestamp Action Category Detail
2023-10-10 Updated TERM virus-mediated perturbation of host defense response
2022-04-05 Updated TERM mitigation of host antiviral defense response
2019-12-12 Updated TERM mitigation of host defenses by virus
2012-08-06 Updated TERM evasion or tolerance of host defenses by virus
2005-12-10 Updated TERM evasion of host defenses by virus
2003-05-17 Updated TERM viral host defense evasion
2001-10-01 Added TERM viral-host defense evasion
Timestamp Action Category Detail
2023-10-10 Deleted DEFINITION A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-10-10 Added DEFINITION A process in which a virus interferes with the ability of the host to mount a defense in response to its presence. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-10-10 Deleted SYNONYM regulation by virus of antiviral response
2023-10-10 Added SYNONYM mitigation of host antiviral defense response
2023-10-10 Added SYNONYM perturbation of host defense response by virus
2023-10-10 Added SYNONYM regulation by virus of antiviral response
2023-02-28 Deleted SYNONYM mitigation of host immune response by virus
2023-02-28 Deleted SYNONYM negative regulation of host intracellular antiviral response by virus
2023-02-28 Deleted SYNONYM inhibition of extracellular antiviral response
2023-02-28 Deleted SYNONYM mitigation by virus of host immune response
2023-02-28 Deleted SYNONYM viral inhibition of intracellular antiviral response
2023-02-28 Deleted SYNONYM suppression by virus of host intracellular antiviral response
2023-02-28 Deleted SYNONYM suppression by virus of host extracellular antiviral response
2023-02-28 Deleted SYNONYM regulation of antiviral response by virus
2023-02-28 Deleted SYNONYM negative regulation of host extracellular antiviral response by virus
2023-02-28 Deleted SYNONYM suppression of host intracellular antiviral response by virus
2023-02-28 Deleted SYNONYM negative regulation by virus of intracellular antiviral response
2023-02-28 Deleted SYNONYM evasion by virus of host immune response
2023-02-28 Deleted SYNONYM evasion or tolerance by virus of host immune response
2023-02-28 Deleted SYNONYM negative regulation by virus of extracellular antiviral response
2023-02-28 Deleted SYNONYM suppression of host extracellular antiviral response by virus
2023-02-28 Deleted SYNONYM suppression by virus of host immune response
2023-02-28 Deleted SYNONYM evasion or tolerance of host defenses by virus
2022-04-05 Added SYNONYM suppression by virus of host immune response
2022-04-05 Added SYNONYM mitigation of host defenses by virus
2022-04-05 Added SYNONYM negative regulation by virus of extracellular antiviral response
2022-04-05 Added SYNONYM viral regulation of antiviral response
2022-04-05 Added SYNONYM evasion or tolerance by virus of host immune response
2022-04-05 Added SYNONYM evasion by virus of host immune response
2022-04-05 Added SYNONYM regulation by virus of antiviral response
2022-04-05 Added SYNONYM regulation of defense response to virus by virus
2022-04-05 Added SYNONYM negative regulation by virus of intracellular antiviral response
2022-04-05 Added SYNONYM suppression of host intracellular antiviral response by virus
2022-04-05 Added SYNONYM negative regulation of host extracellular antiviral response by virus
2022-04-05 Added SYNONYM regulation of antiviral response by virus
2022-04-05 Added SYNONYM mitigation of host immune response by virus
2022-04-05 Added SYNONYM negative regulation of host intracellular antiviral response by virus
2022-04-05 Added SYNONYM inhibition of extracellular antiviral response
2022-04-05 Added SYNONYM mitigation by virus of host immune response
2022-04-05 Added SYNONYM viral inhibition of intracellular antiviral response
2022-04-05 Added SYNONYM suppression by virus of host intracellular antiviral response
2022-04-05 Added SYNONYM suppression by virus of host extracellular antiviral response
2022-04-05 Added SYNONYM suppression of host extracellular antiviral response by virus
2019-12-12 Added DEFINITION A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2019-12-12 Deleted DEFINITION Any process, either active or passive, by which a virus avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2019-12-12 Added SYNONYM evasion or tolerance of host defenses by virus
2012-08-06 Added SYNONYM evasion of host defenses by virus
2012-08-06 Added SYNONYM viral host defense evasion
2012-08-06 Deleted SYNONYM viral host defence evasion
2012-08-06 Deleted SYNONYM viral host defense evasion
2012-08-06 Added SYNONYM viral host defence evasion
2008-05-13 Added DEFINITION Any process, either active or passive, by which a virus avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-05-12 Deleted DEFINITION Any process, either active or passive, by which a virus avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2007-08-09 Added SYNONYM viral host defense evasion
2007-08-09 Deleted SYNONYM viral host defense evasion
2007-08-09 Deleted SYNONYM viral host defence evasion
2007-08-09 Added SYNONYM viral host defence evasion
2007-01-23 Updated DEFINITION Any process, either active or passive, by which a virus avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
2005-12-10 Added SYNONYM viral host defense evasion
2005-02-01 Updated DEFINITION The countering of host defenses by active or passive mechanisms by a virus.
2004-05-29 Added SYNONYM viral host defence evasion
2002-11-27 Added DEFINITION The countering of host defenses by active or passive mechanisms.
Timestamp Action Category Detail
2023-02-28 Added RELATION is a GO:0052031 (symbiont-mediated perturbation of host defense response)
2023-02-28 Deleted RELATION is a GO:0030682 (symbiont-mediated perturbation of host defenses)
2022-04-05 Added RELATION is a GO:0019054 (modulation by virus of host cellular process)
2022-04-05 Deleted RELATION is a GO:0019048 (modulation by virus of host process)
2019-09-29 Deleted RELATION is a GO:0044415 (evasion or tolerance of host defenses)
2019-09-29 Added RELATION is a GO:0030682 (symbiont-mediated perturbation of host defenses)
2008-04-01 Updated RELATION is a GO:0019048 (modulation by virus of host process)
2008-04-01 Updated RELATION is a GO:0044415 (evasion or tolerance of host defenses)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:7742 (Vertebrata)
2024-06-07 Added SUBSET goslim_virus
2022-04-05 Added SECONDARY GO:0050690 (regulation of defense response to virus by virus)
2022-04-05 Added SECONDARY GO:0030683 (mitigation of host immune response by virus)
2022-04-05 Added SECONDARY GO:0019052 (suppression by virus of host intracellular antiviral response)
2022-04-05 Added SECONDARY GO:0019053 (suppression by virus of host extracellular antiviral response)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.