GO:0019213
JSON
deacetylase activity
Molecular Function
Definition (GO:0019213 GONUTS page)
Catalysis of the hydrolysis of an acetyl group from a substrate molecule.
Ancestor Chart
Ancestor chart for GO:0019213
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0019213
Child Term | Relationship to GO:0019213 |
---|---|
5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity
|
is_a |
chitin deacetylase activity
|
is_a |
methylumbelliferyl-acetate deacetylase activity
|
is_a |
N-acetylgalactosaminoglycan deacetylase activity
|
is_a |
negative regulation of deacetylase activity
|
negatively_regulates |
acetoxybutynylbithiophene deacetylase activity
|
is_a |
O-acetyl-ADP-ribose deacetylase activity
|
is_a |
cephalosporin-C deacetylase activity
|
is_a |
heparan sulfate N-deacetylase activity
|
is_a |
acetylornithine deacetylase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q9VUX3 | 7227 | NOTUM_DROME | GO:0019213 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15469839 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.3.1.- | |
EC | 3.1.1.- | |
EC | 3.5.1.- | |
InterPro | IPR010169 | Acetylornithine deacetylase ArgE |
InterPro | IPR020043 | Deacetylase Atu3266-like |
InterPro | IPR023842 | Bacillithiol biosynthesis deacetylase, BshB1 |
InterPro | IPR043697 | N-acetyl-L-citrulline deacetylase ArgE'-like |
Reactome | R-HSA-5689000 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0019213 based on ALL annotations
The top 100 of 701 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
deacetylase activity
|
3,888.28 | 100.00 | 50,135 | 50,135 |
acetylornithine deacetylase activity
|
942.91 | 13.93 | 12,370 | 51,010 |
[heparan sulfate]-glucosamine N-sulfotransferase activity
|
3,640.65 | 10.37 | 5,234 | 5,590 |
bacillithiol biosynthetic process
|
1,849.56 | 9.79 | 5,505 | 11,573 |
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
|
2,827.48 | 9.74 | 5,067 | 6,968 |
heparin biosynthetic process
|
2,674.08 | 8.27 | 4,310 | 6,267 |
heparan sulfate proteoglycan biosynthetic process
|
752.75 | 6.36 | 4,335 | 22,392 |
N-acetylglucosaminylinositol deacetylase activity
|
3,092.35 | 5.98 | 3,046 | 3,830 |
succinyl-diaminopimelate desuccinylase activity
|
489.51 | 5.11 | 3,966 | 31,503 |
mycothiol biosynthetic process
|
757.30 | 4.78 | 2,984 | 15,321 |
Totals | 230960 | 42741424 |
No co-occurrence statistics for GO:0019213 based on MANUAL annotations
The top 100 of 493 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
deacetylase activity
|
7,257.30 | 100.00 | 178 | 178 |
[heparan sulfate]-glucosamine N-sulfotransferase activity
|
7,084.51 | 45.56 | 82 | 84 |
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
|
4,176.86 | 33.76 | 80 | 139 |
protein lysine deacetylase activity
|
1,814.32 | 9.02 | 22 | 88 |
N-acetylglucosamine deacetylase activity
|
5,549.70 | 7.14 | 13 | 17 |
heparan sulfate N-deacetylase activity
|
6,140.79 | 6.11 | 11 | 13 |
spermidine deacetylation
|
5,937.79 | 5.00 | 9 | 11 |
polyamine deacetylation
|
5,937.79 | 5.00 | 9 | 11 |
peptidyl-glutamate ADP-deribosylation
|
3,265.78 | 4.76 | 9 | 20 |
protein de-ADP-ribosylation
|
2,512.14 | 4.62 | 9 | 26 |
Totals | 926 | 8439 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pir | 439 |
Change Log
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- All changes
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-21 | Added | XREF | EC:3.5.1.- |
2024-09-21 | Added | XREF | EC:2.3.1.- |
2024-09-21 | Added | XREF | EC:3.1.1.- |
2024-09-20 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group from a substrate molecule. |
2024-09-20 | Deleted | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2024-09-18 | Deleted | RELATION | is a GO:0016787 (hydrolase activity) |
2024-09-18 | Added | RELATION | is a GO:0160215 (deacylase activity) |
2019-04-01 | Added | XREF | Reactome:R-HSA-5689000 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5689000 |
2018-12-11 | Added | XREF | reactome:R-HSA-5689000 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | deacetylase activity |
2001-10-03 | Added | TERM | deacetylase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-20 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group from a substrate molecule. |
2024-09-20 | Deleted | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2003-09-06 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-18 | Deleted | RELATION | is a GO:0016787 (hydrolase activity) |
2024-09-18 | Added | RELATION | is a GO:0160215 (deacylase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016787 (hydrolase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-21 | Added | XREF | EC:3.5.1.- |
2024-09-21 | Added | XREF | EC:2.3.1.- |
2024-09-21 | Added | XREF | EC:3.1.1.- |
2019-04-01 | Added | XREF | Reactome:R-HSA-5689000 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5689000 |
2018-12-11 | Added | XREF | reactome:R-HSA-5689000 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-04-18 | Updated | SUBSET | goslim_pir |
2008-06-09 | Added | SUBSET | goslim_pir |
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