GO:0019213
JSON
deacetylase activity
Molecular Function
Definition (GO:0019213 GONUTS page)
Catalysis of the hydrolysis of an acetyl group from a substrate molecule.
Ancestor Chart
Ancestor chart for GO:0019213
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0019213
Child Term | Relationship to GO:0019213 |
---|---|
N-acetyl-beta-alanine deacetylase activity
|
is_a |
N-acetylglucosamine-6-phosphate deacetylase activity
|
is_a |
N-acetylglucosamine deacetylase activity
|
is_a |
N-acetyldiaminopimelate deacetylase activity
|
is_a |
cephalosporin-C deacetylase activity
|
is_a |
NAD-dependent protein lysine deacylase activity
|
is_a |
N-acetylglucosaminylphosphatidylinositol deacetylase activity
|
is_a |
acetylspermidine deacetylase activity
|
is_a |
acetylsalicylate deacetylase activity
|
is_a |
protein lysine deacetylase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q9VUX3 | 7227 | NOTUM_DROME | GO:0019213 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15469839 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.3.1.- | |
EC | 3.1.1.- | |
EC | 3.5.1.- | |
InterPro | IPR010169 | Acetylornithine deacetylase ArgE |
InterPro | IPR020043 | Deacetylase Atu3266-like |
InterPro | IPR023842 | Bacillithiol biosynthesis deacetylase, BshB1 |
InterPro | IPR043697 | N-acetyl-L-citrulline deacetylase ArgE'-like |
Reactome | R-HSA-5689000 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0019213 based on ALL annotations
The top 100 of 694 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
deacetylase activity
|
3,878.77 | 100.00 | 51,087 | 51,087 |
acetylornithine deacetylase activity
|
941.73 | 13.92 | 12,571 | 51,777 |
heparan sulfate N-sulfotransferase activity
|
3,624.86 | 10.35 | 5,325 | 5,698 |
bacillithiol biosynthetic process
|
1,843.80 | 9.72 | 5,565 | 11,707 |
heparan sulfate proteoglycan biosynthetic process, chain elongation
|
2,805.75 | 9.72 | 5,159 | 7,132 |
heparin biosynthetic process
|
2,660.44 | 8.02 | 4,256 | 6,205 |
N-acetylglucosaminylinositol deacetylase activity
|
3,127.20 | 6.23 | 3,233 | 4,010 |
heparan sulfate proteoglycan biosynthetic process
|
734.09 | 6.16 | 4,278 | 22,604 |
mycothiol biosynthetic process
|
765.52 | 4.96 | 3,171 | 16,067 |
glycoside metabolic process
|
544.16 | 4.51 | 3,187 | 22,717 |
Totals | 241437 | 41116610 |
No co-occurrence statistics for GO:0019213 based on MANUAL annotations
The top 100 of 487 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
deacetylase activity
|
6,919.28 | 100.00 | 204 | 204 |
heparan sulfate N-sulfotransferase activity
|
6,850.09 | 48.29 | 99 | 100 |
heparan sulfate proteoglycan biosynthetic process, chain elongation
|
4,221.20 | 36.47 | 97 | 159 |
protein lysine deacetylase activity
|
1,710.38 | 8.12 | 22 | 89 |
N-acetylglucosamine deacetylase activity
|
5,291.21 | 6.25 | 13 | 17 |
heparan sulfate N-deacetylase activity
|
6,387.03 | 5.85 | 12 | 13 |
spermidine deacetylation
|
5,661.23 | 4.37 | 9 | 11 |
polyamine deacetylation
|
5,661.23 | 4.37 | 9 | 11 |
peptidyl-glutamate ADP-deribosylation
|
3,113.68 | 4.19 | 9 | 20 |
protein de-ADP-ribosylation
|
2,395.14 | 4.07 | 9 | 26 |
Totals | 988 | 9586 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pir | 438 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-21 | Added | XREF | EC:3.5.1.- |
2024-09-21 | Added | XREF | EC:2.3.1.- |
2024-09-21 | Added | XREF | EC:3.1.1.- |
2024-09-20 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group from a substrate molecule. |
2024-09-20 | Deleted | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2024-09-18 | Added | RELATION | is a GO:0160215 (deacylase activity) |
2024-09-18 | Deleted | RELATION | is a GO:0016787 (hydrolase activity) |
2019-04-01 | Added | XREF | Reactome:R-HSA-5689000 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5689000 |
2018-12-11 | Added | XREF | reactome:R-HSA-5689000 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | deacetylase activity |
2001-10-03 | Added | TERM | deacetylase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-20 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group from a substrate molecule. |
2024-09-20 | Deleted | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
2003-09-06 | Added | DEFINITION | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-18 | Added | RELATION | is a GO:0160215 (deacylase activity) |
2024-09-18 | Deleted | RELATION | is a GO:0016787 (hydrolase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016787 (hydrolase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-21 | Added | XREF | EC:3.5.1.- |
2024-09-21 | Added | XREF | EC:2.3.1.- |
2024-09-21 | Added | XREF | EC:3.1.1.- |
2019-04-01 | Added | XREF | Reactome:R-HSA-5689000 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-5689000 |
2018-12-11 | Added | XREF | reactome:R-HSA-5689000 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-04-18 | Updated | SUBSET | goslim_pir |
2008-06-09 | Added | SUBSET | goslim_pir |
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