This term is obsolete.

GO:0019213 JSON

deacetylase activity

Molecular Function

Definition (GO:0019213 GONUTS page)

Catalysis of the hydrolysis of an acetyl group from a substrate molecule.

552,484 annotations

Ancestor Chart

Ancestor chart for GO:0019213
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019213

Child Term Relationship to
GO:0019213
5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity
is_a
chitin deacetylase activity
is_a
methylumbelliferyl-acetate deacetylase activity
is_a
N-acetylgalactosaminoglycan deacetylase activity
is_a
negative regulation of deacetylase activity
negatively_regulates
acetoxybutynylbithiophene deacetylase activity
is_a
O-acetyl-ADP-ribose deacetylase activity
is_a
cephalosporin-C deacetylase activity
is_a
heparan sulfate N-deacetylase activity
is_a
acetylornithine deacetylase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q9VUX3 7227 NOTUM_DROME GO:0019213 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15469839

Cross-references

Database ID Description
EC 2.3.1.-
EC 3.1.1.-
EC 3.5.1.-
InterPro IPR010169 Acetylornithine deacetylase ArgE
InterPro IPR020043 Deacetylase Atu3266-like
InterPro IPR023842 Bacillithiol biosynthesis deacetylase, BshB1
InterPro IPR043697 N-acetyl-L-citrulline deacetylase ArgE'-like
Reactome R-HSA-5689000

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0019213 based on ALL annotations
The top 100 of 701 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deacetylase activity
3,888.28 100.00 50,135 50,135
acetylornithine deacetylase activity
942.91 13.93 12,370 51,010
[heparan sulfate]-glucosamine N-sulfotransferase activity
3,640.65 10.37 5,234 5,590
bacillithiol biosynthetic process
1,849.56 9.79 5,505 11,573
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
2,827.48 9.74 5,067 6,968
heparin biosynthetic process
2,674.08 8.27 4,310 6,267
heparan sulfate proteoglycan biosynthetic process
752.75 6.36 4,335 22,392
N-acetylglucosaminylinositol deacetylase activity
3,092.35 5.98 3,046 3,830
succinyl-diaminopimelate desuccinylase activity
489.51 5.11 3,966 31,503
mycothiol biosynthetic process
757.30 4.78 2,984 15,321
Totals 230960 42741424
No co-occurrence statistics for GO:0019213 based on MANUAL annotations
The top 100 of 493 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deacetylase activity
7,257.30 100.00 178 178
[heparan sulfate]-glucosamine N-sulfotransferase activity
7,084.51 45.56 82 84
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
4,176.86 33.76 80 139
protein lysine deacetylase activity
1,814.32 9.02 22 88
N-acetylglucosamine deacetylase activity
5,549.70 7.14 13 17
heparan sulfate N-deacetylase activity
6,140.79 6.11 11 13
spermidine deacetylation
5,937.79 5.00 9 11
polyamine deacetylation
5,937.79 5.00 9 11
peptidyl-glutamate ADP-deribosylation
3,265.78 4.76 9 20
protein de-ADP-ribosylation
2,512.14 4.62 9 26
Totals 926 8439

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_pir 439

Change Log

Timestamp Action Category Detail
2024-09-21 Added XREF EC:3.5.1.-
2024-09-21 Added XREF EC:2.3.1.-
2024-09-21 Added XREF EC:3.1.1.-
2024-09-20 Added DEFINITION Catalysis of the hydrolysis of an acetyl group from a substrate molecule.
2024-09-20 Deleted DEFINITION Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
2024-09-18 Deleted RELATION is a GO:0016787 (hydrolase activity)
2024-09-18 Added RELATION is a GO:0160215 (deacylase activity)
2019-04-01 Added XREF Reactome:R-HSA-5689000
2019-04-01 Deleted XREF reactome:R-HSA-5689000
2018-12-11 Added XREF reactome:R-HSA-5689000
Timestamp Action Category Detail
2003-03-19 Updated TERM deacetylase activity
2001-10-03 Added TERM deacetylase
Timestamp Action Category Detail
2024-09-20 Added DEFINITION Catalysis of the hydrolysis of an acetyl group from a substrate molecule.
2024-09-20 Deleted DEFINITION Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
2003-09-06 Added DEFINITION Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
Timestamp Action Category Detail
2024-09-18 Deleted RELATION is a GO:0016787 (hydrolase activity)
2024-09-18 Added RELATION is a GO:0160215 (deacylase activity)
2008-04-01 Updated RELATION is a GO:0016787 (hydrolase activity)
Timestamp Action Category Detail
2024-09-21 Added XREF EC:3.5.1.-
2024-09-21 Added XREF EC:2.3.1.-
2024-09-21 Added XREF EC:3.1.1.-
2019-04-01 Added XREF Reactome:R-HSA-5689000
2019-04-01 Deleted XREF reactome:R-HSA-5689000
2018-12-11 Added XREF reactome:R-HSA-5689000
Timestamp Action Category Detail
2013-04-18 Updated SUBSET goslim_pir
2008-06-09 Added SUBSET goslim_pir
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