This term is obsolete.

GO:0021895 JSON

cerebral cortex neuron differentiation

Biological Process

Definition (GO:0021895 GONUTS page)

The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.

2,352 annotations

Ancestor Chart

Ancestor chart for GO:0021895
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0021895

Child Term Relationship to
GO:0021895
GO:0097410
hippocampal interneuron differentiation
is_a
GO:0097432
hippocampal pyramidal neuron differentiation
is_a
GO:0021892
cerebral cortex GABAergic interneuron differentiation
is_a
GO:0021870
Cajal-Retzius cell differentiation
is_a
GO:1905270
Meynert cell differentiation
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0021895 cerebral cortex neuron differentiation Only in Taxon 7711 Chordata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q54NG5 44689 Q54NG5_DICDI GO:0007417 To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 IPR034968
IEA Review protein Q54NG6 44689 Q54NG6_DICDI GO:0007417 To remove over-annotation from InterPro entries. Reported by Typhaine from InterPro on 08/06/2020 IPR034968
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P0CI71 10116 K0319_RAT GO:0022008 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q2EI20 7955 REST_DANRE GO:0022008 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:22951640
NOT-qualified manual protein Q5SZV5 10090 K0319_MOUSE GO:0022008 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27510895
NOT-qualified manual protein Q9VIP7 7227 ACASE_DROME GO:0007420 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:21148295

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0010012 cerebral cortex neuron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0021895 based on ALL annotations
The top 100 of 474 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0021895
cerebral cortex neuron differentiation
183,137.58 100.00 1,082 1,082
GO:0021795
cerebral cortex cell migration
34,380.43 8.77 153 815
GO:0097154
GABAergic neuron differentiation
29,505.50 8.75 174 1,080
GO:0021537
telencephalon development
22,168.82 8.62 249 2,057
GO:0002364
NK T cell lineage commitment
183,137.58 8.60 93 93
GO:0002362
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
177,414.52 8.57 93 96
GO:0021872
forebrain generation of neurons
177,414.52 8.57 93 96
GO:0043373
CD4-positive, alpha-beta T cell lineage commitment
160,677.30 8.49 93 106
GO:0021877
forebrain neuron fate commitment
171,322.25 8.00 87 93
GO:0043375
CD8-positive, alpha-beta T cell lineage commitment
94,098.32 7.95 93 181
Totals 10605 128831
No co-occurrence statistics for GO:0021895 based on MANUAL annotations
The top 100 of 420 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0021895
cerebral cortex neuron differentiation
23,139.89 100.00 61 61
GO:0002364
NK T cell lineage commitment
23,139.89 11.48 7 7
GO:0021853
cerebral cortex GABAergic interneuron migration
9,743.11 11.11 8 19
GO:0043375
CD8-positive, alpha-beta T cell lineage commitment
17,997.69 11.11 7 9
GO:0002362
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
16,197.92 10.94 7 10
GO:1902232
regulation of positive thymic T cell selection
14,725.38 10.77 7 11
GO:0021877
forebrain neuron fate commitment
12,459.94 10.45 7 13
GO:0043373
CD4-positive, alpha-beta T cell lineage commitment
10,123.70 10.00 7 16
GO:0021872
forebrain generation of neurons
15,426.59 9.38 6 9
GO:0060164
regulation of timing of neuron differentiation
11,569.94 8.96 6 12
Totals 538 6723

Change Log

Timestamp Action Category Detail
2025-01-23 Deleted RELATION is a GO:0021953 (central nervous system neuron differentiation)
2025-01-23 Deleted RELATION part of GO:0030900 (forebrain development)
2025-01-23 Added RELATION is a GO:0021879 (forebrain neuron differentiation)
2024-03-22 Deleted CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-03-22 Added CONSTRAINT in_taxon NCBITaxon:7711 (Chordata)
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
2010-04-30 Added RELATION is a GO:0021953 (central nervous system neuron differentiation)
2010-04-30 Deleted RELATION is a GO:0030182 (neuron differentiation)
Timestamp Action Category Detail
2006-08-17 Added TERM cerebral cortex neuron differentiation
Timestamp Action Category Detail
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
2008-05-12 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
2006-08-18 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
Timestamp Action Category Detail
2025-01-23 Deleted RELATION is a GO:0021953 (central nervous system neuron differentiation)
2025-01-23 Deleted RELATION part of GO:0030900 (forebrain development)
2025-01-23 Added RELATION is a GO:0021879 (forebrain neuron differentiation)
2010-04-30 Added RELATION is a GO:0021953 (central nervous system neuron differentiation)
2010-04-30 Deleted RELATION is a GO:0030182 (neuron differentiation)
2008-07-11 Deleted RELATION is a GO:0030154 (cell differentiation)
2008-07-11 Added RELATION is a GO:0030182 (neuron differentiation)
2008-04-01 Updated RELATION part of GO:0030900 (forebrain development)
2008-04-01 Updated RELATION is a GO:0030154 (cell differentiation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-22 Deleted CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-03-22 Added CONSTRAINT in_taxon NCBITaxon:7711 (Chordata)
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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