GO:0030196
JSON
cyanide hydratase activity
Molecular Function
Definition (GO:0030196 GONUTS page)
Catalysis of the reaction: formamide = H2O + hydrogen cyanide.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
formamide hydro-lyase (cyanide-forming) | related |
formamide hydro-lyase activity | related |
formamide dehydratase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.2.1.66 | |
InterPro | IPR037544 | Cyanide hydratase |
KEGG_REACTION | R01408 | |
MetaCyc | CYANIDE-HYDRATASE-RXN | |
RHEA | 21720 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:16397 | formamide |
has_participant | CHEBI | CHEBI:18407 | hydrogen cyanide |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0030196 based on ALL annotations
The top 26 of 26 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cyanide hydratase activity
|
397,901.34 | 100.00 | 498 | 498 |
cyanide catabolic process
|
393,107.34 | 97.62 | 492 | 498 |
nitrilase activity
|
11,062.84 | 2.77 | 460 | 16,545 |
hydro-lyase activity
|
631.60 | 0.16 | 461 | 290,423 |
detoxification of nitrogen compound
|
164.56 | 0.03 | 1 | 2,418 |
lyase activity
|
43.81 | 0.01 | 498 | 4,523,172 |
nitrile hydratase activity
|
41.25 | 0.01 | 1 | 9,646 |
cellular_component
|
25.43 | 0.01 | 4 | 62,590 |
Hsp70 protein binding
|
7.05 | 0.00 | 1 | 56,437 |
response to heat
|
2.86 | 0.00 | 1 | 139,351 |
Totals | 2493 | 151165073 |
No co-occurrence statistics for GO:0030196 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Totals | 0 | 0 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: formamide = H2O + hydrogen cyanide. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide. |
2020-10-08 | Added | SYNONYM | formamide hydro-lyase activity |
2020-10-08 | Deleted | SYNONYM | formamide dehydratase activity |
2020-10-08 | Deleted | SYNONYM | formamide hydro-lyase (cyanide-forming) |
2020-10-08 | Deleted | SYNONYM | formamide hydro-lyase activity |
2020-10-08 | Added | SYNONYM | formamide dehydratase activity |
2020-10-08 | Added | SYNONYM | formamide hydro-lyase (cyanide-forming) |
2019-06-20 | Added | XREF | KEGG_REACTION:R01408 |
2019-06-20 | Deleted | XREF | KEGG:R01408 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | cyanide hydratase activity |
2001-08-30 | Added | TERM | cyanide hydratase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: formamide = H2O + hydrogen cyanide. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide. |
2020-10-08 | Added | SYNONYM | formamide hydro-lyase activity |
2020-10-08 | Deleted | SYNONYM | formamide dehydratase activity |
2020-10-08 | Deleted | SYNONYM | formamide hydro-lyase (cyanide-forming) |
2020-10-08 | Deleted | SYNONYM | formamide hydro-lyase activity |
2020-10-08 | Added | SYNONYM | formamide dehydratase activity |
2020-10-08 | Added | SYNONYM | formamide hydro-lyase (cyanide-forming) |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide. |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: formamide = cyanide + H2O. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: formamide = cyanide + H2O. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: formamide = cyanide + H2O. |
2007-11-08 | Added | SYNONYM | formamide hydro-lyase (cyanide-forming) |
2007-09-06 | Deleted | SYNONYM | formamide hydro-lyase |
2007-09-06 | Added | SYNONYM | formamide dehydratase activity |
2007-09-06 | Added | SYNONYM | formamide hydro-lyase activity |
2007-09-06 | Deleted | SYNONYM | formamide dehydratase |
2007-08-09 | Deleted | SYNONYM | formamide hydro-lyase |
2007-08-09 | Added | SYNONYM | formamide hydro-lyase |
2007-08-09 | Added | SYNONYM | formamide dehydratase |
2007-08-09 | Deleted | SYNONYM | formamide dehydratase |
2004-04-19 | Added | SYNONYM | formamide dehydratase |
2004-04-19 | Added | SYNONYM | formamide hydro-lyase |
2004-04-16 | Deleted | SYNONYM | formamide dehydratase |
2004-04-16 | Deleted | SYNONYM | formamide hydro-lyase |
2003-10-27 | Added | SYNONYM | formamide hydro-lyase |
2003-10-27 | Added | SYNONYM | formamide dehydratase |
2003-08-21 | Deleted | SYNONYM | formamide dehydratase |
2003-08-21 | Deleted | SYNONYM | formamide hydro-lyase |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: formamide = cyanide + H2O. |
2001-08-30 | Added | SYNONYM | formamide hydro-lyase |
2001-08-30 | Added | SYNONYM | formamide dehydratase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016836 (hydro-lyase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Added | XREF | KEGG_REACTION:R01408 |
2019-06-20 | Deleted | XREF | KEGG:R01408 |
2018-07-13 | Deleted | XREF | RHEA:21723 |
2018-07-13 | Added | XREF | RHEA:21720 |
2010-10-11 | Added | XREF | KEGG:R01408 |
2010-10-11 | Added | XREF | RHEA:21723 |
2003-10-27 | Added | XREF | MetaCyc:CYANIDE-HYDRATASE-RXN |
2001-08-30 | Added | XREF | EC:4.2.1.66 |
Timestamp | Action | Category | Detail |
---|
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