This term is obsolete.

GO:0030196 JSON

cyanide hydratase activity

Molecular Function

Definition (GO:0030196 GONUTS page)

Catalysis of the reaction: formamide = H2O + hydrogen cyanide.

498 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
formamide hydro-lyase (cyanide-forming) related
formamide hydro-lyase activity related
formamide dehydratase activity related

Ancestor Chart

Ancestor chart for GO:0030196
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.2.1.66
InterPro IPR037544 Cyanide hydratase
KEGG_REACTION R01408
MetaCyc CYANIDE-HYDRATASE-RXN
RHEA 21720

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:16397 formamide
has_participant CHEBI CHEBI:18407 hydrogen cyanide

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030196 based on ALL annotations
The top 26 of 26 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cyanide hydratase activity
397,901.34 100.00 498 498
cyanide catabolic process
393,107.34 97.62 492 498
nitrilase activity
11,062.84 2.77 460 16,545
hydro-lyase activity
631.60 0.16 461 290,423
detoxification of nitrogen compound
164.56 0.03 1 2,418
lyase activity
43.81 0.01 498 4,523,172
nitrile hydratase activity
41.25 0.01 1 9,646
cellular_component
25.43 0.01 4 62,590
Hsp70 protein binding
7.05 0.00 1 56,437
response to heat
2.86 0.00 1 139,351
Totals 2493 151165073
No co-occurrence statistics for GO:0030196 based on MANUAL annotations
The top 0 of 0 co-occurring terms
Co-occurring Term PR S% #Together #Compared
Totals 0 0

Change Log

Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: formamide = H2O + hydrogen cyanide.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.
2020-10-08 Added SYNONYM formamide hydro-lyase activity
2020-10-08 Deleted SYNONYM formamide dehydratase activity
2020-10-08 Deleted SYNONYM formamide hydro-lyase (cyanide-forming)
2020-10-08 Deleted SYNONYM formamide hydro-lyase activity
2020-10-08 Added SYNONYM formamide dehydratase activity
2020-10-08 Added SYNONYM formamide hydro-lyase (cyanide-forming)
2019-06-20 Added XREF KEGG_REACTION:R01408
2019-06-20 Deleted XREF KEGG:R01408
Timestamp Action Category Detail
2003-03-19 Updated TERM cyanide hydratase activity
2001-08-30 Added TERM cyanide hydratase
Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: formamide = H2O + hydrogen cyanide.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.
2020-10-08 Added SYNONYM formamide hydro-lyase activity
2020-10-08 Deleted SYNONYM formamide dehydratase activity
2020-10-08 Deleted SYNONYM formamide hydro-lyase (cyanide-forming)
2020-10-08 Deleted SYNONYM formamide hydro-lyase activity
2020-10-08 Added SYNONYM formamide dehydratase activity
2020-10-08 Added SYNONYM formamide hydro-lyase (cyanide-forming)
2010-10-11 Added DEFINITION Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.
2010-10-11 Deleted DEFINITION Catalysis of the reaction: formamide = cyanide + H2O.
2008-05-13 Added DEFINITION Catalysis of the reaction: formamide = cyanide + H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: formamide = cyanide + H2O.
2007-11-08 Added SYNONYM formamide hydro-lyase (cyanide-forming)
2007-09-06 Deleted SYNONYM formamide hydro-lyase
2007-09-06 Added SYNONYM formamide dehydratase activity
2007-09-06 Added SYNONYM formamide hydro-lyase activity
2007-09-06 Deleted SYNONYM formamide dehydratase
2007-08-09 Deleted SYNONYM formamide hydro-lyase
2007-08-09 Added SYNONYM formamide hydro-lyase
2007-08-09 Added SYNONYM formamide dehydratase
2007-08-09 Deleted SYNONYM formamide dehydratase
2004-04-19 Added SYNONYM formamide dehydratase
2004-04-19 Added SYNONYM formamide hydro-lyase
2004-04-16 Deleted SYNONYM formamide dehydratase
2004-04-16 Deleted SYNONYM formamide hydro-lyase
2003-10-27 Added SYNONYM formamide hydro-lyase
2003-10-27 Added SYNONYM formamide dehydratase
2003-08-21 Deleted SYNONYM formamide dehydratase
2003-08-21 Deleted SYNONYM formamide hydro-lyase
2002-11-27 Added DEFINITION Catalysis of the reaction: formamide = cyanide + H2O.
2001-08-30 Added SYNONYM formamide hydro-lyase
2001-08-30 Added SYNONYM formamide dehydratase
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016836 (hydro-lyase activity)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R01408
2019-06-20 Deleted XREF KEGG:R01408
2018-07-13 Deleted XREF RHEA:21723
2018-07-13 Added XREF RHEA:21720
2010-10-11 Added XREF KEGG:R01408
2010-10-11 Added XREF RHEA:21723
2003-10-27 Added XREF MetaCyc:CYANIDE-HYDRATASE-RXN
2001-08-30 Added XREF EC:4.2.1.66
Timestamp Action Category Detail
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