This term is obsolete.

GO:0030202 JSON

heparin metabolic process

Biological Process

Definition (GO:0030202 GONUTS page)

The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.

6,951 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
heparin metabolism exact
heparan sulfate metabolic process related

Ancestor Chart

Ancestor chart for GO:0030202
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030202

Child Term Relationship to
GO:0030202
heparin biosynthetic process
is_a
heparin catabolic process
is_a

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:24505 heparins

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030202 based on ALL annotations
The top 100 of 344 co-occurring terms
Co-occurring Term PR S% #Together #Compared
heparin metabolic process
352,511.38 100.00 553 553
renal albumin absorption
178,140.75 25.61 189 374
left ventricular cardiac muscle tissue morphogenesis
174,860.52 25.27 188 379
regulation of protein localization to cell leading edge
349,055.38 18.23 101 102
podocyte apoptotic process
332,744.38 18.07 101 107
lymphocyte adhesion to endothelial cell of high endothelial venule
352,511.34 15.91 88 88
perichondral bone morphogenesis
352,511.34 15.91 88 88
hypersensitivity
352,511.34 15.91 88 88
enteric smooth muscle cell differentiation
352,511.34 15.91 88 88
smoothened signaling pathway involved in lung development
352,511.34 15.91 88 88
Totals 10654 57898
No co-occurrence statistics for GO:0030202 based on MANUAL annotations
The top 100 of 316 co-occurring terms
Co-occurring Term PR S% #Together #Compared
heparin metabolic process
64,589.95 100.00 20 20
response to disaccharide
64,589.95 25.00 5 5
alpha-N-acetylglucosaminidase activity
46,135.68 22.73 5 7
obsolete sequestering of iron ion
46,135.68 22.73 5 7
rod bipolar cell differentiation
40,368.72 21.74 5 8
left ventricular cardiac muscle tissue morphogenesis
21,529.98 20.59 7 21
lymphocyte adhesion to endothelial cell of high endothelial venule
64,589.95 20.00 4 4
sweat gland development
64,589.95 20.00 4 4
perichondral bone morphogenesis
64,589.95 20.00 4 4
hypersensitivity
64,589.95 20.00 4 4
Totals 425 3483

Change Log

Timestamp Action Category Detail
2020-11-03 Deleted RELATION is a GO:0043436 (oxoacid metabolic process)
2016-11-28 Added RELATION is a GO:0043436 (oxoacid metabolic process)
2016-06-22 Deleted RELATION is a GO:0043436 (oxoacid metabolic process)
2014-10-05 Deleted RELATION is a GO:0030203 (glycosaminoglycan metabolic process)
2014-10-05 Added RELATION is a GO:1903510 (mucopolysaccharide metabolic process)
2012-11-02 Added RELATION is a GO:0043436 (oxoacid metabolic process)
2011-10-28 Deleted DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2011-10-28 Added DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2009-07-06 Added RELATION is a GO:0006790 (sulfur compound metabolic process)
2008-06-03 Added SYNONYM heparan sulfate metabolic process
Timestamp Action Category Detail
2007-01-15 Updated TERM heparin metabolic process
2001-09-01 Added TERM heparin metabolism
Timestamp Action Category Detail
2011-10-28 Deleted DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2011-10-28 Added DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2008-06-03 Added SYNONYM heparan sulfate metabolic process
2008-05-13 Added DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2007-08-09 Deleted SYNONYM heparin metabolism
2007-08-09 Added SYNONYM heparin metabolism
2007-01-29 Added SYNONYM heparin metabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2005-01-21 Updated DEFINITION The chemical reactions involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2002-11-27 Added DEFINITION The chemical reactions and physical changes involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
Timestamp Action Category Detail
2020-11-03 Deleted RELATION is a GO:0043436 (oxoacid metabolic process)
2016-11-28 Added RELATION is a GO:0043436 (oxoacid metabolic process)
2016-06-22 Deleted RELATION is a GO:0043436 (oxoacid metabolic process)
2014-10-05 Deleted RELATION is a GO:0030203 (glycosaminoglycan metabolic process)
2014-10-05 Added RELATION is a GO:1903510 (mucopolysaccharide metabolic process)
2012-11-02 Added RELATION is a GO:0043436 (oxoacid metabolic process)
2009-07-06 Added RELATION is a GO:0006790 (sulfur compound metabolic process)
2008-04-01 Updated RELATION is a GO:0030203 (glycosaminoglycan metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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