This term is obsolete.

GO:0030210 JSON

heparin biosynthetic process

Biological Process

Definition (GO:0030210 GONUTS page)

The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.

6,287 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
heparin formation exact
heparin biosynthesis exact
heparan sulfate biosynthetic process related
heparin synthesis exact
heparin anabolism exact

Ancestor Chart

Ancestor chart for GO:0030210
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Ancestor chart

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_output CHEBI CHEBI:24505 heparins

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030210 based on ALL annotations
The top 100 of 370 co-occurring terms
Co-occurring Term PR S% #Together #Compared
heparin biosynthetic process
31,105.60 100.00 6,267 6,267
[heparan sulfate]-glucosamine N-sulfotransferase activity
24,044.24 57.34 4,321 5,590
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
19,396.36 48.88 4,345 6,968
heparan sulfate proteoglycan biosynthetic process
8,427.91 26.85 6,067 22,392
heparosan-N-sulfate-glucuronate 5-epimerase activity
16,544.57 19.42 1,468 2,760
deacetylase activity
2,674.08 8.27 4,310 50,135
heparan sulfate N-deacetylase activity
29,377.51 4.60 289 306
N-acetylglucosamine deacetylase activity
28,964.27 4.09 257 276
fluid transport
17,888.20 2.81 180 313
endochondral bone morphogenesis
12,251.66 2.75 180 457
Totals 36998 295646
No co-occurrence statistics for GO:0030210 based on MANUAL annotations
The top 100 of 206 co-occurring terms
Co-occurring Term PR S% #Together #Compared
heparin biosynthetic process
56,165.18 100.00 23 23
fluid transport
25,274.33 26.47 9 20
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
21,061.94 23.68 9 24
lymphocyte adhesion to endothelial cell of high endothelial venule
56,165.17 17.39 4 4
sweat gland development
56,165.17 17.39 4 4
perichondral bone morphogenesis
56,165.17 17.39 4 4
hypersensitivity
56,165.17 17.39 4 4
smoothened signaling pathway involved in lung development
56,165.17 17.39 4 4
stomach development
37,443.45 16.00 4 6
response to leukemia inhibitory factor
37,443.45 16.00 4 6
Totals 461 8971

Change Log

Timestamp Action Category Detail
2017-08-13 Deleted RELATION is a GO:0044711 (obsolete single-organism biosynthetic process)
2016-11-28 Added RELATION is a GO:0044711 (obsolete single-organism biosynthetic process)
2011-10-28 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2011-10-28 Added DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2009-10-29 Added RELATION is a GO:0044272 (sulfur compound biosynthetic process)
2008-06-03 Added SYNONYM heparan sulfate biosynthetic process
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2008-04-01 Updated RELATION is a GO:0006024 (glycosaminoglycan biosynthetic process)
2008-04-01 Updated RELATION is a GO:0030202 (heparin metabolic process)
Timestamp Action Category Detail
2007-01-15 Updated TERM heparin biosynthetic process
2001-09-01 Added TERM heparin biosynthesis
Timestamp Action Category Detail
2011-10-28 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2011-10-28 Added DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2008-06-03 Added SYNONYM heparan sulfate biosynthetic process
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2007-08-09 Deleted SYNONYM heparin synthesis
2007-08-09 Deleted SYNONYM heparin formation
2007-08-09 Deleted SYNONYM heparin anabolism
2007-08-09 Deleted SYNONYM heparin biosynthesis
2007-08-09 Added SYNONYM heparin formation
2007-08-09 Added SYNONYM heparin biosynthesis
2007-08-09 Added SYNONYM heparin anabolism
2007-08-09 Added SYNONYM heparin synthesis
2007-01-15 Added SYNONYM heparin biosynthesis
2006-05-04 Updated DEFINITION The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2005-08-10 Added SYNONYM heparin formation
2005-08-10 Added SYNONYM heparin synthesis
2005-08-10 Added SYNONYM heparin anabolism
2002-11-27 Added DEFINITION The formation from simpler components of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
Timestamp Action Category Detail
2017-08-13 Deleted RELATION is a GO:0044711 (obsolete single-organism biosynthetic process)
2016-11-28 Added RELATION is a GO:0044711 (obsolete single-organism biosynthetic process)
2009-10-29 Added RELATION is a GO:0044272 (sulfur compound biosynthetic process)
2008-04-01 Updated RELATION is a GO:0006024 (glycosaminoglycan biosynthetic process)
2008-04-01 Updated RELATION is a GO:0030202 (heparin metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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