GO:0030219
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megakaryocyte differentiation
Biological Process
Definition (GO:0030219 GONUTS page)
The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
megakaryocyte cell differentiation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0030219
Child Term | Relationship to GO:0030219 |
---|---|
regulation of megakaryocyte differentiation
|
regulates |
negative regulation of megakaryocyte differentiation
|
negatively_regulates |
positive regulation of megakaryocyte differentiation
|
positively_regulates |
megakaryocyte development
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0030219 | megakaryocyte differentiation | Only in Taxon | 6072 | Eumetazoa |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | E9PTS6 | 10116 | E9PTS6_RAT | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P01127 | 9606 | PDGFB_HUMAN | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163 | |
NOT-qualified manual | protein | P05622 | 10090 | PGFRB_MOUSE | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163 | |
NOT-qualified manual | protein | P12919 | 9685 | PDGFB_FELCA | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | P31240 | 10090 | PDGFB_MOUSE | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q05028 | 10116 | PDGFB_RAT | GO:0030097 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_acquisition_of_features_of | CL | CL:0000556 | megakaryocyte |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0030219 based on ALL annotations
The top 100 of 268 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
megakaryocyte differentiation
|
130,132.70 | 100.00 | 1,498 | 1,498 |
basophil differentiation
|
130,132.70 | 11.62 | 174 | 174 |
erythrocyte differentiation
|
14,510.33 | 10.85 | 1,198 | 10,744 |
regulation of definitive erythrocyte differentiation
|
81,608.64 | 9.33 | 148 | 236 |
platelet formation
|
18,087.25 | 8.98 | 303 | 2,180 |
megakaryocyte development
|
18,378.50 | 8.82 | 285 | 2,018 |
primitive erythrocyte differentiation
|
22,923.10 | 6.17 | 130 | 738 |
positive regulation of macromolecule biosynthetic process
|
8,615.98 | 6.14 | 685 | 10,346 |
positive regulation of chromatin organization
|
130,132.70 | 5.87 | 88 | 88 |
regulation of mast cell differentiation
|
130,132.70 | 5.87 | 88 | 88 |
Totals | 13746 | 444087 |
No co-occurrence statistics for GO:0030219 based on MANUAL annotations
The top 100 of 241 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
megakaryocyte differentiation
|
18,454.27 | 100.00 | 70 | 70 |
megakaryocyte development
|
2,516.49 | 9.78 | 18 | 132 |
regulation of definitive erythrocyte differentiation
|
9,936.92 | 9.21 | 7 | 13 |
peptidyl-cysteine S-nitrosylase activity
|
4,370.75 | 9.09 | 9 | 38 |
biliverdin reductase [NAD(P)+] activity
|
3,460.18 | 8.26 | 9 | 48 |
cellular response to cell-matrix adhesion
|
5,871.81 | 8.24 | 7 | 22 |
protein K69-linked ufmylation
|
3,785.49 | 7.92 | 8 | 39 |
enucleate erythrocyte differentiation
|
4,968.46 | 7.87 | 7 | 26 |
erythrocyte differentiation
|
1,511.34 | 7.66 | 38 | 464 |
positive regulation of megakaryocyte differentiation
|
2,460.57 | 7.41 | 10 | 75 |
Totals | 631 | 12050 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2016-06-22 | Deleted | RELATION | is a GO:0002244 (hematopoietic progenitor cell differentiation) |
2013-10-24 | Added | RELATION | is a GO:0002244 (hematopoietic progenitor cell differentiation) |
2010-12-01 | Added | DEFINITION | The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2010-12-01 | Deleted | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2008-05-13 | Added | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2008-05-12 | Deleted | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2008-04-01 | Updated | RELATION | is a GO:0030099 (myeloid cell differentiation) |
2007-08-09 | Added | SYNONYM | megakaryocyte cell differentiation |
2007-08-09 | Deleted | SYNONYM | megakaryocyte cell differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-02-21 | Updated | TERM | megakaryocyte differentiation |
2005-01-16 | Updated | TERM | megakaryocyte cell differentiation |
2001-09-05 | Added | TERM | megakaryocyte differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-01 | Added | DEFINITION | The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2010-12-01 | Deleted | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2008-05-13 | Added | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2008-05-12 | Deleted | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2007-08-09 | Added | SYNONYM | megakaryocyte cell differentiation |
2007-08-09 | Deleted | SYNONYM | megakaryocyte cell differentiation |
2006-04-22 | Updated | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2005-02-21 | Added | SYNONYM | megakaryocyte cell differentiation |
2005-01-21 | Updated | DEFINITION | Processes by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
2002-11-27 | Added | DEFINITION | The process by which a myeloid precursor cell acquires specializes features of a megakaryocyte. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-06-22 | Deleted | RELATION | is a GO:0002244 (hematopoietic progenitor cell differentiation) |
2013-10-24 | Added | RELATION | is a GO:0002244 (hematopoietic progenitor cell differentiation) |
2008-04-01 | Updated | RELATION | is a GO:0030099 (myeloid cell differentiation) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
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