GO:0030266
JSON
quinate 3-dehydrogenase (NAD+) activity
Molecular Function
Definition (GO:0030266 GONUTS page)
Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
quinic dehydrogenase activity | broad |
quinate:NAD 3-oxidoreductase activity | exact |
quinate:NAD(+) 3-oxidoreductase activity | exact |
quinate:NAD 5-oxidoreductase activity | related |
quinate:NAD(+) 5-oxidoreductase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4KZV0 | 6945 | A0A1S4KZV0_IXOSC | GO:0016616 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.1.1.24 | |
EC | 1.1.1.282 | |
InterPro | IPR022872 | Quinate/Shikimate dehydrogenase |
KEGG_REACTION | R01872 | |
MetaCyc | QUINATE-5-DEHYDROGENASE-RXN | |
RHEA | 22364 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57540 | NAD(1-) |
has_participant | CHEBI | CHEBI:29751 | (-)-quinate |
has_participant | CHEBI | CHEBI:57945 | NADH(2-) |
has_participant | CHEBI | CHEBI:32364 | 3-dehydroquinate |
has_participant | CHEBI | CHEBI:15378 | hydron |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0033706 | obsolete quinate/shikimate dehydrogenase activity | consider GO:0030266 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0030266 based on ALL annotations
The top 28 of 28 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
quinate 3-dehydrogenase (NAD+) activity
|
296,195.60 | 100.00 | 669 | 669 |
shikimate 3-dehydrogenase (NAD+) activity
|
296,195.60 | 97.76 | 654 | 654 |
quinate 3-dehydrogenase (NADP+) activity
|
296,195.60 | 97.31 | 651 | 651 |
shikimate metabolic process
|
3,145.68 | 1.06 | 646 | 60,827 |
shikimate 3-dehydrogenase (NADP+) activity
|
3,056.27 | 1.03 | 664 | 64,351 |
chorismate biosynthetic process
|
630.67 | 0.21 | 646 | 303,395 |
aromatic amino acid family biosynthetic process
|
459.41 | 0.16 | 608 | 391,996 |
amino acid biosynthetic process
|
216.89 | 0.07 | 584 | 797,531 |
quinate metabolic process
|
193.72 | 0.05 | 2 | 3,058 |
3,4-dihydroxybenzoate biosynthetic process
|
43.81 | 0.01 | 2 | 13,522 |
Totals | 5998 | 115890304 |
No co-occurrence statistics for GO:0030266 based on MANUAL annotations
The top 10 of 10 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
quinate 3-dehydrogenase (NAD+) activity
|
282,306.60 | 100.00 | 5 | 5 |
shikimate 3-dehydrogenase (NAD+) activity
|
282,306.62 | 20.00 | 1 | 1 |
shikimate metabolic process
|
6,819.00 | 2.42 | 5 | 207 |
quinate catabolic process
|
7,429.12 | 2.38 | 1 | 38 |
chorismate biosynthetic process
|
3,016.10 | 1.07 | 5 | 468 |
shikimate 3-dehydrogenase (NADP+) activity
|
2,795.11 | 0.98 | 2 | 202 |
NAD+ binding
|
839.37 | 0.30 | 3 | 1,009 |
protein homodimerization activity
|
53.72 | 0.02 | 1 | 5,255 |
protein binding
|
6.75 | 0.00 | 1 | 41,833 |
cellular_component
|
4.51 | 0.00 | 1 | 62,590 |
Totals | 25 | 111608 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | quinate:NAD 5-oxidoreductase activity |
2020-10-08 | Added | SYNONYM | quinate:NAD(+) 5-oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | quinate:NAD 5-oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | quinate:NAD(+) 5-oxidoreductase activity |
2019-06-20 | Deleted | XREF | KEGG:R01872 |
2019-06-20 | Added | XREF | KEGG_REACTION:R01872 |
2018-07-13 | Deleted | XREF | RHEA:22367 |
2018-07-13 | Added | XREF | RHEA:22364 |
2011-08-19 | Added | XREF | RHEA:22367 |
2011-08-19 | Added | XREF | EC:1.1.1.282 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-19 | Updated | TERM | quinate 3-dehydrogenase (NAD+) activity |
2003-03-19 | Updated | TERM | quinate 5-dehydrogenase activity |
2001-10-01 | Added | TERM | quinate 5-dehydrogenase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | quinate:NAD 5-oxidoreductase activity |
2020-10-08 | Added | SYNONYM | quinate:NAD(+) 5-oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | quinate:NAD 5-oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | quinate:NAD(+) 5-oxidoreductase activity |
2011-08-19 | Deleted | SYNONYM | quinate:NAD oxidoreductase activity |
2011-08-19 | Deleted | DEFINITION | Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+. |
2011-08-19 | Added | SYNONYM | quinate:NAD 3-oxidoreductase activity |
2011-08-19 | Added | SYNONYM | quinic dehydrogenase activity |
2011-08-19 | Added | SYNONYM | quinate:NAD(+) 3-oxidoreductase activity |
2011-08-19 | Added | SYNONYM | quinate:NAD 5-oxidoreductase activity |
2011-08-19 | Deleted | SYNONYM | quinic dehydrogenase activity |
2011-08-19 | Added | DEFINITION | Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+. |
2007-09-06 | Added | SYNONYM | quinate:NAD(+) 5-oxidoreductase activity |
2007-09-06 | Added | SYNONYM | quinic dehydrogenase activity |
2007-09-06 | Added | SYNONYM | quinate:NAD oxidoreductase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R01872 |
2019-06-20 | Added | XREF | KEGG_REACTION:R01872 |
2018-07-13 | Deleted | XREF | RHEA:22367 |
2018-07-13 | Added | XREF | RHEA:22364 |
2011-08-19 | Added | XREF | RHEA:22367 |
2011-08-19 | Added | XREF | EC:1.1.1.282 |
2011-08-19 | Added | XREF | KEGG:R01872 |
2003-10-27 | Added | XREF | MetaCyc:QUINATE-5-DEHYDROGENASE-RXN |
2001-10-01 | Added | XREF | EC:1.1.1.24 |
Timestamp | Action | Category | Detail |
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