GO:0030297
JSON
transmembrane receptor protein tyrosine kinase activator activity
Molecular Function
Definition (GO:0030297 GONUTS page)
Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.
Ancestor Chart
Ancestor chart for GO:0030297
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0005155 | obsolete epidermal growth factor receptor activating ligand activity | consider GO:0030297 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0030297 based on ALL annotations
The top 100 of 773 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
transmembrane receptor protein tyrosine kinase activator activity
|
120,406.91 | 100.00 | 1,619 | 1,619 |
ERBB2-EGFR signaling pathway
|
88,028.59 | 28.82 | 522 | 714 |
ERBB2-ERBB4 signaling pathway
|
51,219.87 | 10.18 | 191 | 449 |
ERBB4-ERBB4 signaling pathway
|
45,338.41 | 9.52 | 183 | 486 |
mammary gland alveolus development
|
20,183.82 | 8.37 | 232 | 1,384 |
positive regulation of mitotic nuclear division
|
9,586.86 | 6.66 | 470 | 5,903 |
epidermal growth factor receptor binding
|
7,339.79 | 5.52 | 598 | 9,810 |
positive regulation of peptidyl-tyrosine phosphorylation
|
6,717.68 | 5.07 | 578 | 10,360 |
VEGF-A complex
|
120,406.90 | 4.88 | 79 | 79 |
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
|
118,901.82 | 4.88 | 79 | 80 |
Totals | 13550 | 155205 |
No co-occurrence statistics for GO:0030297 based on MANUAL annotations
The top 100 of 691 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
transmembrane receptor protein tyrosine kinase activator activity
|
15,378.56 | 100.00 | 84 | 84 |
ERBB2-EGFR signaling pathway
|
12,884.74 | 34.44 | 31 | 37 |
multivesicular body, internal vesicle lumen
|
14,097.01 | 12.94 | 11 | 12 |
negative regulation of cardiocyte differentiation
|
14,097.01 | 12.94 | 11 | 12 |
response to hydroxyisoflavone
|
14,097.01 | 12.94 | 11 | 12 |
positive regulation of prolactin secretion
|
13,012.63 | 12.79 | 11 | 13 |
ERBB4-ERBB4 signaling pathway
|
7,381.71 | 12.37 | 12 | 25 |
diterpenoid metabolic process
|
9,398.01 | 12.09 | 11 | 18 |
morphogenesis of an epithelial fold
|
7,354.96 | 11.46 | 11 | 23 |
response to cobalamin
|
5,126.19 | 10.38 | 11 | 33 |
Totals | 1089 | 14601 |
Change Log
- All changes
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- Term
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-16 | Deleted | RELATION | part of GO:0007171 (activation of transmembrane receptor protein tyrosine kinase activity) |
2018-04-27 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2017-05-05 | Deleted | RELATION | regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2017-05-01 | Added | RELATION | regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2017-05-01 | Added | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2016-11-28 | Deleted | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2016-03-02 | Added | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2015-07-11 | Added | DEFINITION | Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. |
2015-07-11 | Deleted | DEFINITION | Increases the activity of a transmembrane receptor protein tyrosine kinase. |
2012-02-03 | Added | RELATION | part of GO:0007171 (activation of transmembrane receptor protein tyrosine kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | transmembrane receptor protein tyrosine kinase activator activity |
2001-10-01 | Added | TERM | transmembrane receptor protein tyrosine kinase activator |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-07-11 | Added | DEFINITION | Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. |
2015-07-11 | Deleted | DEFINITION | Increases the activity of a transmembrane receptor protein tyrosine kinase. |
2009-06-11 | Added | DEFINITION | Increases the activity of a transmembrane receptor protein tyrosine kinase. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-16 | Deleted | RELATION | part of GO:0007171 (activation of transmembrane receptor protein tyrosine kinase activity) |
2018-04-27 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2017-05-05 | Deleted | RELATION | regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2017-05-01 | Added | RELATION | regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2017-05-01 | Added | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2016-11-28 | Deleted | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2016-03-02 | Added | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2012-02-03 | Added | RELATION | part of GO:0007171 (activation of transmembrane receptor protein tyrosine kinase activity) |
2010-06-15 | Added | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2010-06-14 | Deleted | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2010-06-08 | Added | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2009-02-25 | Deleted | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2009-02-22 | Added | RELATION | positively regulates GO:0004714 (transmembrane receptor protein tyrosine kinase activity) |
2008-05-01 | Added | RELATION | is a GO:0030546 (signaling receptor activator activity) |
2008-04-01 | Updated | RELATION | is a GO:0030296 (protein tyrosine kinase activator activity) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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