This term is obsolete.

GO:0030522 JSON

intracellular receptor signaling pathway

Biological Process

Definition (GO:0030522 GONUTS page)

The series of molecular signals initiated by a ligand binding to a receptor located within a cell.

213,758 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
intracellular receptor mediated signaling pathway exact
intracellular receptor-mediated signalling pathway exact
intracellular receptor-mediated signaling pathway exact

Ancestor Chart

Ancestor chart for GO:0030522
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030522

Child Term Relationship to
GO:0030522
GO:0141193
nuclear receptor-mediated signaling pathway
is_a
GO:0009785
blue light signaling pathway
is_a
GO:0035626
juvenile hormone mediated signaling pathway
is_a
GO:0002753
cytoplasmic pattern recognition receptor signaling pathway
is_a
GO:0004879
nuclear receptor activity
part_of

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Cross-references

Database ID Description
Reactome R-HSA-9024446

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor consider GO:0030522
GO:0072500 obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor consider GO:0030522
GO:2000190 obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor consider GO:0030522

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030522 based on ALL annotations
The top 100 of 1,426 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0030522
intracellular receptor signaling pathway
4,411.78 100.00 44,915 44,915
GO:0004879
nuclear receptor activity
3,426.77 77.34 44,666 57,505
GO:0009755
hormone-mediated signaling pathway
1,331.94 16.68 12,197 40,400
GO:0050728
negative regulation of inflammatory response
1,578.74 13.19 7,761 21,688
GO:0034751
aryl hydrocarbon receptor complex
4,194.41 12.25 5,538 5,825
GO:0009410
response to xenobiotic stimulus
1,454.80 10.11 5,713 17,325
GO:0035259
nuclear glucocorticoid receptor binding
1,768.40 8.56 4,406 10,992
GO:0010887
negative regulation of cholesterol storage
3,756.52 8.48 3,864 4,538
GO:0090575
RNA polymerase II transcription regulator complex
588.08 8.28 8,053 60,414
GO:0071376
cellular response to corticotropin-releasing hormone stimulus
1,495.56 8.25 4,413 13,018
Totals 507491 42790479
No co-occurrence statistics for GO:0030522 based on MANUAL annotations
The top 100 of 705 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0030522
intracellular receptor signaling pathway
4,188.53 100.00 337 337
GO:0004879
nuclear receptor activity
889.65 21.03 322 1,516
GO:0045923
positive regulation of fatty acid metabolic process
3,269.09 18.03 64 82
GO:0010887
negative regulation of cholesterol storage
2,455.34 17.66 68 116
GO:0050728
negative regulation of inflammatory response
695.06 13.83 153 922
GO:0010883
regulation of lipid storage
1,311.56 7.65 31 99
GO:0070644
vitamin D response element binding
3,071.59 6.38 22 30
GO:0010875
positive regulation of cholesterol efflux
672.77 6.21 31 193
GO:0009755
hormone-mediated signaling pathway
279.74 6.15 148 2,216
GO:0030154
cell differentiation
182.52 4.34 306 7,022
Totals 3192 87351

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-9024446
2024-06-11 Deleted RELATION is a GO:0007165 (signal transduction)
2024-06-11 Added RELATION is a GO:0035556 (intracellular signal transduction)
2022-03-14 Added DEFINITION The series of molecular signals initiated by a ligand binding to a receptor located within a cell.
2022-03-14 Deleted DEFINITION Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
2013-04-20 Updated TERM intracellular receptor signaling pathway
2013-04-20 Added SYNONYM intracellular receptor mediated signaling pathway
2011-01-16 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2011-01-16 Added RELATION is a GO:0007165 (signal transduction)
2010-05-16 Added DEFINITION Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
Timestamp Action Category Detail
2013-04-20 Updated TERM intracellular receptor signaling pathway
2010-04-21 Updated TERM intracellular receptor mediated signaling pathway
2002-01-19 Added TERM intracellular receptor-mediated signaling pathway
Timestamp Action Category Detail
2022-03-14 Added DEFINITION The series of molecular signals initiated by a ligand binding to a receptor located within a cell.
2022-03-14 Deleted DEFINITION Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
2013-04-20 Added SYNONYM intracellular receptor mediated signaling pathway
2010-05-16 Added DEFINITION Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
2010-05-16 Deleted DEFINITION Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
2010-04-21 Added SYNONYM intracellular receptor-mediated signaling pathway
2008-05-13 Added DEFINITION Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
2008-05-12 Deleted DEFINITION Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
2007-08-09 Added SYNONYM intracellular receptor-mediated signalling pathway
2007-08-09 Deleted SYNONYM intracellular receptor-mediated signalling pathway
2004-07-17 Updated DEFINITION Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
2004-04-19 Added SYNONYM intracellular receptor-mediated signalling pathway
2004-04-16 Deleted SYNONYM intracellular receptor-mediated signalling pathway
2003-11-13 Added SYNONYM intracellular receptor-mediated signalling pathway
2002-11-27 Added DEFINITION A signaling pathway initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
Timestamp Action Category Detail
2024-06-11 Deleted RELATION is a GO:0007165 (signal transduction)
2024-06-11 Added RELATION is a GO:0035556 (intracellular signal transduction)
2011-01-16 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2011-01-16 Added RELATION is a GO:0007165 (signal transduction)
2010-04-21 Deleted RELATION is a GO:0007242 (intracellular signaling cascade)
2010-04-21 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2008-04-01 Updated RELATION is a GO:0007242 (intracellular signaling cascade)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-9024446
Timestamp Action Category Detail
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