This term is obsolete.

GO:0030851 JSON

granulocyte differentiation

Biological Process

Definition (GO:0030851 GONUTS page)

The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.

3,385 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
granulocyte cell differentiation exact

Ancestor Chart

Ancestor chart for GO:0030851
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0030851

Child Term Relationship to
GO:0030851
regulation of granulocyte differentiation
regulates
positive regulation of granulocyte differentiation
positively_regulates
eosinophil differentiation
is_a
neutrophil differentiation
is_a
basophil differentiation
is_a
negative regulation of granulocyte differentiation
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0030851 granulocyte differentiation Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein E9PTS6 10116 E9PTS6_RAT GO:0030097 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P01127 9606 PDGFB_HUMAN GO:0030097 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163
NOT-qualified manual protein P05622 10090 PGFRB_MOUSE GO:0030097 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163
NOT-qualified manual protein P12919 9685 PDGFB_FELCA GO:0030097 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein P31240 10090 PDGFB_MOUSE GO:0030097 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q05028 10116 PDGFB_RAT GO:0030097 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000094 granulocyte

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0030851 based on ALL annotations
The top 100 of 607 co-occurring terms
Co-occurring Term PR S% #Together #Compared
granulocyte differentiation
161,239.69 100.00 1,209 1,209
macrophage differentiation
27,277.93 12.38 382 2,258
embryonic process involved in female pregnancy
43,312.69 7.76 119 443
establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
146,728.12 7.47 91 100
plasmacytoid dendritic cell differentiation
81,496.15 7.15 93 184
negative regulation of leukocyte activation
80,188.72 7.14 93 187
positive regulation of dendritic cell differentiation
78,509.38 7.12 93 191
neutrophil differentiation
19,448.27 6.98 172 1,426
embryonic placenta development
20,634.45 6.87 156 1,219
ATP-dependent protein disaggregase activity
80,619.85 6.86 89 178
Totals 10683 120117
No co-occurrence statistics for GO:0030851 based on MANUAL annotations
The top 100 of 546 co-occurring terms
Co-occurring Term PR S% #Together #Compared
granulocyte differentiation
17,223.99 100.00 75 75
embryonic process involved in female pregnancy
4,697.45 9.09 9 33
embryonic camera-type eye morphogenesis
2,327.57 7.19 10 74
megakaryocyte differentiation
2,214.51 6.62 9 70
cardiac neural crest cell development involved in heart development
9,568.88 6.33 5 9
macrophage differentiation
1,398.90 6.25 16 197
trophectodermal cell differentiation
1,823.72 5.96 9 85
regulation of primitive erythrocyte differentiation
5,382.50 5.81 5 16
exocrine pancreas development
1,609.72 5.81 10 107
embryonic placenta development
1,424.54 5.58 11 133
Totals 594 7236

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2010-12-01 Deleted DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2010-12-01 Added DEFINITION The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2008-05-13 Added DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2008-05-12 Deleted DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2008-04-01 Updated RELATION is a GO:0002573 (myeloid leukocyte differentiation)
2007-08-09 Deleted SYNONYM granulocyte cell differentiation
2007-08-09 Added SYNONYM granulocyte cell differentiation
2005-02-21 Updated TERM granulocyte differentiation
2005-02-21 Added SYNONYM granulocyte cell differentiation
Timestamp Action Category Detail
2005-02-21 Updated TERM granulocyte differentiation
2005-01-13 Updated TERM granulocyte cell differentiation
2003-09-06 Added TERM granulocyte differentiation
Timestamp Action Category Detail
2010-12-01 Deleted DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2010-12-01 Added DEFINITION The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2008-05-13 Added DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2008-05-12 Deleted DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2007-08-09 Deleted SYNONYM granulocyte cell differentiation
2007-08-09 Added SYNONYM granulocyte cell differentiation
2005-02-21 Added SYNONYM granulocyte cell differentiation
2005-01-21 Updated DEFINITION The process by which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
2003-09-06 Added DEFINITION The process by which a myeloid precursor cell acquires specializes features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0002573 (myeloid leukocyte differentiation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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