This term is obsolete.

GO:0031000 JSON

response to caffeine

Biological Process

Definition (GO:0031000 GONUTS page)

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.

806 annotations

Ancestor Chart

Ancestor chart for GO:0031000
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0031000

Child Term Relationship to
GO:0031000
cellular response to caffeine
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Response to guidelines Link

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:27732 caffeine

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0031000 based on ALL annotations
The top 100 of 1,367 co-occurring terms
Co-occurring Term PR S% #Together #Compared
response to caffeine
802,217.25 100.00 243 243
establishment of protein localization to endoplasmic reticulum
802,217.25 34.57 84 84
suramin binding
765,752.80 34.01 84 88
regulation of AV node cell action potential
317,859.66 22.64 84 212
Purkinje myocyte to ventricular cardiac muscle cell signaling
786,487.50 20.49 50 51
regulation of SA node cell action potential
265,300.20 20.34 84 254
regulation of atrial cardiac muscle cell action potential
259,177.88 20.05 84 260
type B pancreatic cell apoptotic process
256,221.47 19.91 84 263
positive regulation of the force of heart contraction
240,665.16 19.13 84 280
calcium-induced calcium release activity
200,554.31 17.26 87 348
Totals 2762 47979
No co-occurrence statistics for GO:0031000 based on MANUAL annotations
The top 100 of 1,227 co-occurring terms
Co-occurring Term PR S% #Together #Compared
response to caffeine
19,572.71 100.00 66 66
'de novo' UMP biosynthetic process
9,320.34 12.99 10 21
UTP biosynthetic process
10,362.02 12.16 9 17
response to cortisol
4,760.93 9.57 9 37
response to amine
4,296.45 9.18 9 41
response to trehalose
11,743.63 8.57 6 10
detection of chemical stimulus involved in sensory perception of sweet taste
9,033.56 8.22 6 13
response to alcohol
2,644.96 7.69 10 74
epigenetic programming of gene expression
5,338.01 7.32 6 22
gene silencing by piRNA-directed DNA methylation
12,232.95 7.25 5 8
Totals 599 7544

Change Log

Timestamp Action Category Detail
2020-06-02 Deleted RELATION is a GO:0036270 (response to diuretic)
2020-06-02 Deleted RELATION is a GO:0009410 (response to xenobiotic stimulus)
2017-11-29 Added RELATION is a GO:0036270 (response to diuretic)
2017-11-29 Added RELATION is a GO:0009410 (response to xenobiotic stimulus)
2011-05-08 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2011-05-08 Added DEFINITION Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2008-05-13 Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2008-05-12 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2008-04-01 Updated RELATION is a GO:0043279 (response to alkaloid)
2008-04-01 Updated RELATION is a GO:0014074 (response to purine-containing compound)
Timestamp Action Category Detail
2004-09-24 Added TERM response to caffeine
Timestamp Action Category Detail
2011-05-08 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2011-05-08 Added DEFINITION Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2008-05-13 Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2008-05-12 Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2007-06-27 Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
2005-09-20 Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus.
2005-09-15 Updated DEFINITION A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perception of, or exposure to, caffeine.
2004-09-24 Added DEFINITION A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to caffeine.
Timestamp Action Category Detail
2020-06-02 Deleted RELATION is a GO:0036270 (response to diuretic)
2020-06-02 Deleted RELATION is a GO:0009410 (response to xenobiotic stimulus)
2017-11-29 Added RELATION is a GO:0036270 (response to diuretic)
2017-11-29 Added RELATION is a GO:0009410 (response to xenobiotic stimulus)
2008-04-01 Updated RELATION is a GO:0043279 (response to alkaloid)
2008-04-01 Updated RELATION is a GO:0014074 (response to purine-containing compound)
Timestamp Action Category Detail
Timestamp Action Category Detail
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