GO:0031419
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cobalamin binding
Molecular Function
Definition (GO:0031419 GONUTS page)
Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
vitamin B12 binding | exact |
Ancestor Chart
Ancestor chart for GO:0031419
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR002157 | Cobalamin (vitamin B12)-binding protein |
InterPro | IPR003206 | Diol/glycerol dehydratase, large subunit |
InterPro | IPR006098 | Methylmalonyl-CoA mutase, alpha chain, catalytic |
InterPro | IPR006099 | Methylmalonyl-CoA mutase, alpha/beta chain, catalytic |
InterPro | IPR006158 | Cobalamin (vitamin B12)-binding domain |
InterPro | IPR011822 | Cobalamin-dependent methionine synthase |
InterPro | IPR012741 | Methyltransferase cognate corrinoid protein |
InterPro | IPR013344 | Ribonucleotide reductase, adenosylcobalamin-dependent |
InterPro | IPR013345 | Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent |
InterPro | IPR014714 | Glutamate mutase E subunit, C-terminal domain superfamily |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:30411 | cobalamin |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0031419 based on ALL annotations
The top 100 of 611 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cobalamin binding
|
714.31 | 100.00 | 272,906 | 272,906 |
methylmalonyl-CoA mutase activity
|
713.64 | 16.17 | 44,125 | 44,166 |
homocysteine metabolic process
|
506.09 | 16.16 | 47,254 | 66,695 |
methionine synthase activity
|
465.46 | 15.99 | 47,711 | 73,219 |
tetrahydrofolate metabolic process
|
213.44 | 12.29 | 47,148 | 157,790 |
pteridine-containing compound metabolic process
|
520.93 | 10.85 | 30,853 | 42,306 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
|
178.31 | 9.13 | 34,337 | 137,553 |
propionate metabolic process, methylmalonyl pathway
|
714.31 | 7.30 | 19,922 | 19,922 |
methionine biosynthetic process
|
74.08 | 6.96 | 47,711 | 460,052 |
epoxyqueuosine reductase activity
|
309.90 | 5.34 | 15,650 | 36,073 |
Totals | 1654015 | 195741287 |
No co-occurrence statistics for GO:0031419 based on MANUAL annotations
The top 83 of 83 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
cobalamin binding
|
10,171.65 | 100.00 | 127 | 127 |
cobalamin transport
|
6,517.75 | 40.24 | 66 | 103 |
methylmalonyl-CoA mutase activity
|
10,171.65 | 35.43 | 45 | 45 |
propionate metabolic process, methylmalonyl pathway
|
10,171.65 | 33.07 | 42 | 42 |
cargo receptor ligand activity
|
7,911.28 | 5.43 | 7 | 9 |
cobalamin metabolic process
|
1,312.47 | 4.42 | 8 | 62 |
corrinoid adenosyltransferase activity
|
984.35 | 3.28 | 6 | 62 |
succinyl-CoA biosynthetic process
|
10,171.65 | 3.15 | 4 | 4 |
pivalyl-CoA mutase activity
|
8,137.32 | 3.13 | 4 | 5 |
transferase activity, transferring alkyl or aryl (other than methyl) groups
|
762.87 | 2.99 | 6 | 80 |
Totals | 628 | 792030 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-12 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2021-05-24 | Added | DEFINITION | Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2020-06-02 | Deleted | RELATION | is a GO:0008144 (obsolete drug binding) |
2020-05-08 | Deleted | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2020-02-28 | Deleted | XREF | MIPS_funcat:16.21.09 |
2019-05-04 | Added | XREF | MIPS_funcat:16.21.09 |
2017-11-29 | Added | RELATION | is a GO:0008144 (obsolete drug binding) |
2017-11-29 | Added | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2009-07-06 | Added | RELATION | is a GO:0046906 (tetrapyrrole binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-05-16 | Added | TERM | cobalamin binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2021-05-24 | Added | DEFINITION | Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2008-10-02 | Deleted | DEFINITION | Interacting lelectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2008-10-02 | Added | DEFINITION | Interacting selectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2008-05-13 | Added | DEFINITION | Interacting lelectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2008-05-12 | Deleted | DEFINITION | Interacting lelectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2007-08-09 | Added | SYNONYM | vitamin B12 binding |
2007-08-09 | Deleted | SYNONYM | vitamin B12 binding |
2005-05-16 | Added | DEFINITION | Interacting lelectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
2005-05-16 | Added | SYNONYM | vitamin B12 binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-12 | Added | RELATION | is a GO:1901363 (heterocyclic compound binding) |
2020-06-02 | Deleted | RELATION | is a GO:0008144 (obsolete drug binding) |
2020-05-08 | Deleted | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2017-11-29 | Added | RELATION | is a GO:0008144 (obsolete drug binding) |
2017-11-29 | Added | RELATION | is a GO:0048037 (obsolete cofactor binding) |
2009-07-06 | Added | RELATION | is a GO:0046906 (tetrapyrrole binding) |
2008-04-01 | Updated | RELATION | is a GO:0019842 (vitamin binding) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-02-28 | Deleted | XREF | MIPS_funcat:16.21.09 |
2019-05-04 | Added | XREF | MIPS_funcat:16.21.09 |
Timestamp | Action | Category | Detail |
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