GO:0031508
JSON
pericentric heterochromatin formation
Biological Process
Definition (GO:0031508 GONUTS page)
The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA. PMID:14612388 PMID:20206496 PMID:22729156
Secondary IDs
GO:0030702, GO:1990141
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
chromatin silencing at centromere outer repeat region | narrow |
heterochromatic silencing at centromere | exact |
centromeric heterochromatin formation | exact |
pericentric heterochromatin assembly | exact |
centromeric heterochromatin biosynthesis | exact |
centromere chromatin silencing | exact |
centromeric silencing | exact |
chromatin silencing at pericentric region | related |
centric heterochromatin formation | related |
chromatin silencing at centromere | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0031508
Child Term | Relationship to GO:0031508 |
---|---|
positive regulation of pericentric heterochromatin formation
|
positively_regulates |
siRNA-mediated pericentric heterochromatin formation
|
is_a |
regulation of pericentric heterochromatin formation
|
regulates |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | O94603 | 284812 | JHD1_SCHPO | GO:0031507 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:25831549 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q15170 | 9606 | TCAL1_HUMAN | GO:0010629 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:7971997 | |
NOT-qualified manual | protein | Q8INR6 | 7227 | DOT1L_DROME | GO:0031508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15371351 | |
NOT-qualified manual | protein | Q90998 | 9031 | Q90998_CHICK | GO:0010468 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q90999 | 9031 | TGFR2_CHICK | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q96AE4 | 9606 | FUBP1_HUMAN | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259 | |
NOT-qualified manual | protein | Q9USK2 | 284812 | SET9_SCHPO | GO:0031508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243 | |
NOT-qualified manual | protein | Q9USK2 | 284812 | SET9_SCHPO | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0031508 based on ALL annotations
The top 100 of 565 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pericentric heterochromatin formation
|
52,986.90 | 100.00 | 3,679 | 3,679 |
lymphocyte proliferation
|
36,604.61 | 31.02 | 1,325 | 1,918 |
pericentric heterochromatin
|
16,877.36 | 28.20 | 2,616 | 8,213 |
DNA methylation-dependent constitutive heterochromatin formation
|
11,571.79 | 19.14 | 2,235 | 10,234 |
mating-type region heterochromatin
|
16,172.89 | 17.55 | 1,075 | 3,522 |
subtelomeric heterochromatin
|
45,317.74 | 5.25 | 195 | 228 |
negative regulation of gene expression via chromosomal CpG island methylation
|
2,847.40 | 5.19 | 2,237 | 41,628 |
heterochromatin island
|
34,035.38 | 4.66 | 176 | 274 |
chromosome, subtelomeric region
|
16,613.05 | 4.64 | 190 | 606 |
siRNA-independent facultative heterochromatin formation
|
27,373.90 | 4.45 | 171 | 331 |
Totals | 28896 | 1550662 |
No co-occurrence statistics for GO:0031508 based on MANUAL annotations
The top 100 of 412 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pericentric heterochromatin formation
|
14,848.27 | 100.00 | 87 | 87 |
mating-type region heterochromatin
|
6,705.67 | 23.14 | 28 | 62 |
lymphocyte proliferation
|
5,345.38 | 15.13 | 18 | 50 |
subtelomeric heterochromatin
|
8,315.03 | 14.29 | 14 | 25 |
subtelomeric heterochromatin formation
|
1,922.32 | 10.28 | 29 | 224 |
histone H3K56 deacetylase activity, NAD-dependent
|
14,848.26 | 9.20 | 8 | 8 |
pericentric heterochromatin
|
1,361.09 | 8.41 | 44 | 480 |
silent mating-type cassette heterochromatin formation
|
2,211.44 | 8.38 | 14 | 94 |
ketone biosynthetic process
|
12,992.23 | 7.95 | 7 | 8 |
chromosome, subtelomeric region
|
4,949.42 | 7.77 | 8 | 24 |
Totals | 739 | 6931 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-02-28 | Deleted | RELATION | part of GO:0034508 (centromere complex assembly) |
2023-01-16 | Deleted | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
2022-08-26 | Added | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
2022-07-02 | Added | DEFINITION | The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA. |
2022-07-02 | Deleted | DEFINITION | The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA. |
2022-07-02 | Updated | TERM | pericentric heterochromatin formation |
2022-07-02 | Added | SYNONYM | pericentric heterochromatin assembly |
2022-06-26 | Deleted | RELATION | is a GO:0031055 (chromatin remodeling at centromere) |
2022-06-26 | Deleted | RELATION | is a GO:0140462 (pericentric heterochromatin organization) |
2021-11-22 | Deleted | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-02 | Updated | TERM | pericentric heterochromatin formation |
2014-08-22 | Updated | TERM | pericentric heterochromatin assembly |
2011-11-30 | Updated | TERM | centromeric heterochromatin assembly |
2010-03-20 | Updated | TERM | centromeric heterochromatin formation |
2010-01-22 | Updated | TERM | centromeric heterochromatin assembly |
2008-06-14 | Updated | TERM | centromeric heterochromatin formation |
2005-06-23 | Added | TERM | centric heterochromatin formation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-02 | Added | DEFINITION | The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA. |
2022-07-02 | Deleted | DEFINITION | The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA. |
2022-07-02 | Added | SYNONYM | pericentric heterochromatin assembly |
2020-04-06 | Added | DEFINITION | The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA. |
2020-04-06 | Deleted | DEFINITION | The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA |
2020-03-30 | Added | DEFINITION | The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA |
2020-03-30 | Deleted | DEFINITION | The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3. |
2020-03-30 | Added | SYNONYM | centromere chromatin silencing |
2020-03-30 | Added | SYNONYM | centromeric silencing |
2020-03-30 | Added | SYNONYM | chromatin silencing at centromere outer repeat region |
2020-03-30 | Added | SYNONYM | chromatin silencing at pericentric region |
2020-03-30 | Added | SYNONYM | chromatin silencing at centromere |
2020-03-30 | Added | SYNONYM | heterochromatic silencing at centromere |
2014-08-22 | Added | DEFINITION | The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3. |
2014-08-22 | Deleted | DEFINITION | The assembly of chromatin into heterochromatin near the centromere. |
2011-11-30 | Deleted | SYNONYM | centromeric heterochromatin assembly |
2011-11-30 | Added | SYNONYM | centromeric heterochromatin formation |
2010-01-22 | Added | SYNONYM | centric heterochromatin formation |
2010-01-22 | Deleted | SYNONYM | centric heterochromatin formation |
2008-06-14 | Added | SYNONYM | centromeric heterochromatin assembly |
2008-06-14 | Added | SYNONYM | centric heterochromatin formation |
2008-06-14 | Deleted | SYNONYM | centromeric heterochromatin formation |
2008-06-14 | Deleted | SYNONYM | centric heterochromatin assembly |
2008-05-13 | Added | DEFINITION | The assembly of chromatin into heterochromatin near the centromere. |
2008-05-12 | Deleted | DEFINITION | The assembly of chromatin into heterochromatin near the centromere. |
2007-08-09 | Deleted | SYNONYM | centric heterochromatin assembly |
2007-08-09 | Deleted | SYNONYM | centromeric heterochromatin formation |
2007-08-09 | Added | SYNONYM | centric heterochromatin assembly |
2007-08-09 | Added | SYNONYM | centromeric heterochromatin biosynthesis |
2007-08-09 | Added | SYNONYM | centromeric heterochromatin formation |
2007-08-09 | Deleted | SYNONYM | centromeric heterochromatin biosynthesis |
2007-01-15 | Added | SYNONYM | centromeric heterochromatin biosynthesis |
2005-07-04 | Added | SYNONYM | centric heterochromatin assembly |
2005-06-23 | Added | SYNONYM | centromeric heterochromatin formation |
2005-06-23 | Added | DEFINITION | The assembly of chromatin into heterochromatin near the centromere. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-02-28 | Deleted | RELATION | part of GO:0034508 (centromere complex assembly) |
2023-01-16 | Deleted | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
2022-08-26 | Added | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
2022-06-26 | Deleted | RELATION | is a GO:0031055 (chromatin remodeling at centromere) |
2022-06-26 | Deleted | RELATION | is a GO:0140462 (pericentric heterochromatin organization) |
2021-11-22 | Deleted | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
2021-11-22 | Added | RELATION | is a GO:0140719 (constitutive heterochromatin formation) |
2021-11-15 | Added | RELATION | is a GO:0031048 (regulatory ncRNA-mediated heterochromatin formation) |
2021-11-15 | Deleted | RELATION | is a GO:0031507 (heterochromatin formation) |
2021-11-01 | Deleted | RELATION | is a GO:0010629 (negative regulation of gene expression) |
2021-11-01 | Deleted | RELATION | is a GO:0031497 (chromatin assembly) |
2021-11-01 | Added | RELATION | is a GO:0031507 (heterochromatin formation) |
2021-08-30 | Deleted | RELATION | is a GO:0031507 (heterochromatin formation) |
2021-08-30 | Added | RELATION | is a GO:0031497 (chromatin assembly) |
2020-05-09 | Added | RELATION | is a GO:0140462 (pericentric heterochromatin organization) |
2020-04-24 | Added | RELATION | is a GO:0010629 (negative regulation of gene expression) |
2020-04-24 | Deleted | RELATION | is a GO:0006342 (chromatin silencing) |
2020-03-30 | Added | RELATION | is a GO:0006342 (chromatin silencing) |
2008-06-14 | Added | RELATION | part of GO:0034508 (centromere complex assembly) |
2008-04-01 | Updated | RELATION | is a GO:0031507 (heterochromatin formation) |
2008-04-01 | Updated | RELATION | is a GO:0031055 (chromatin remodeling at centromere) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-03-30 | Added | SECONDARY | GO:0030702 (chromatin silencing at centromere) |
2020-03-30 | Added | SECONDARY | GO:1990141 (chromatin silencing at centromere outer repeat region) |
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