GO:0031519
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PcG protein complex
Cellular Component
Definition (GO:0031519 GONUTS page)
A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. PMID:9372908
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Polycomb Group protein complex | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0031519
Child Term | Relationship to GO:0031519 |
---|---|
ESC/E(Z) complex
|
is_a |
PRC1 complex
|
is_a |
PR-DUB complex
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0031519 | PcG protein complex | Never in Taxon | 4890 | Ascomycota | |
GO:0031519 | PcG protein complex | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR025778 | Histone-lysine N-methyltransferase, plant |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0031519 based on ALL annotations
The top 100 of 536 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
PcG protein complex
|
6,488.23 | 100.00 | 30,045 | 30,045 |
transcription regulator complex
|
664.63 | 9.75 | 20,098 | 196,199 |
PRC1 complex
|
1,239.39 | 6.72 | 2,821 | 14,768 |
chromatin
|
380.64 | 5.71 | 20,591 | 350,981 |
ubiquitin ligase complex
|
306.37 | 3.21 | 2,739 | 58,005 |
histone H3K27 methyltransferase activity
|
865.10 | 2.96 | 1,100 | 8,250 |
histone H3K27 trimethyltransferase activity
|
1,331.10 | 2.23 | 732 | 3,568 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding
|
123.61 | 1.89 | 20,168 | 1,058,587 |
heterochromatin formation
|
193.63 | 1.73 | 1,181 | 39,573 |
promoter-specific chromatin binding
|
274.76 | 1.53 | 702 | 16,577 |
Totals | 190577 | 19771848 |
No co-occurrence statistics for GO:0031519 based on MANUAL annotations
The top 100 of 319 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
PcG protein complex
|
3,744.35 | 100.00 | 345 | 345 |
PRC1 complex
|
930.97 | 14.68 | 91 | 366 |
histone H2AK119 ubiquitin ligase activity
|
720.07 | 4.66 | 20 | 104 |
ubiquitin-protein transferase activator activity
|
1,802.83 | 3.62 | 13 | 27 |
POZ domain binding
|
1,521.14 | 3.57 | 13 | 32 |
X chromosome
|
1,058.18 | 3.44 | 13 | 46 |
transcription regulator complex
|
135.13 | 3.39 | 124 | 3,436 |
heterochromatin
|
221.30 | 3.36 | 25 | 423 |
sex chromatin
|
1,797.29 | 3.35 | 12 | 25 |
pole plasm assembly
|
1,497.74 | 3.31 | 12 | 30 |
Totals | 1811 | 78066 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_pir | 439 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2024-04-04 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4890 (Ascomycota) |
2020-11-03 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2020-11-03 | Deleted | RELATION | is a GO:0032991 (protein-containing complex) |
2020-11-03 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2019-09-12 | Added | RELATION | part of GO:0005634 (nucleus) |
2019-09-12 | Deleted | RELATION | is a GO:0044428 (obsolete nuclear part) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-04-18 | Updated | SUBSET | goslim_pir |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-07-23 | Added | TERM | PcG protein complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. |
2008-05-12 | Deleted | DEFINITION | A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. |
2007-08-09 | Deleted | SYNONYM | Polycomb Group protein complex |
2007-08-09 | Added | SYNONYM | Polycomb Group protein complex |
2005-07-23 | Added | SYNONYM | Polycomb Group protein complex |
2005-07-23 | Added | DEFINITION | A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-11-03 | Deleted | RELATION | part of GO:0005634 (nucleus) |
2020-11-03 | Deleted | RELATION | is a GO:0032991 (protein-containing complex) |
2020-11-03 | Added | RELATION | is a GO:0140513 (nuclear protein-containing complex) |
2019-09-12 | Added | RELATION | part of GO:0005634 (nucleus) |
2019-09-12 | Deleted | RELATION | is a GO:0044428 (obsolete nuclear part) |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044428 (obsolete nuclear part) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2024-04-04 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4890 (Ascomycota) |
2013-04-18 | Updated | SUBSET | goslim_pir |
2008-06-09 | Added | SUBSET | goslim_pir |
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