This term is obsolete.

GO:0031519 JSON

PcG protein complex

Cellular Component

Definition (GO:0031519 GONUTS page)

A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. PMID:9372908

61,793 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Polycomb Group protein complex exact

Ancestor Chart

Ancestor chart for GO:0031519
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0031519

Child Term Relationship to
GO:0031519
ESC/E(Z) complex
is_a
PRC1 complex
is_a
PR-DUB complex
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0031519 PcG protein complex Never in Taxon 4890 Ascomycota
GO:0031519 PcG protein complex Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JW23 10116 A0A0G2JW23_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K8T1 10116 A0A0G2K8T1_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GR71 10090 A0A1B0GR71_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1B0GRK6 10090 A0A1B0GRK6_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y8H4 10116 A0A8I5Y8H4_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A0E5 10116 A0A8I6A0E5_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR025778 Histone-lysine N-methyltransferase, plant

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0031519 based on ALL annotations
The top 100 of 536 co-occurring terms
Co-occurring Term PR S% #Together #Compared
PcG protein complex
6,488.23 100.00 30,045 30,045
transcription regulator complex
664.63 9.75 20,098 196,199
PRC1 complex
1,239.39 6.72 2,821 14,768
chromatin
380.64 5.71 20,591 350,981
ubiquitin ligase complex
306.37 3.21 2,739 58,005
histone H3K27 methyltransferase activity
865.10 2.96 1,100 8,250
histone H3K27 trimethyltransferase activity
1,331.10 2.23 732 3,568
RNA polymerase II cis-regulatory region sequence-specific DNA binding
123.61 1.89 20,168 1,058,587
heterochromatin formation
193.63 1.73 1,181 39,573
promoter-specific chromatin binding
274.76 1.53 702 16,577
Totals 190577 19771848
No co-occurrence statistics for GO:0031519 based on MANUAL annotations
The top 100 of 319 co-occurring terms
Co-occurring Term PR S% #Together #Compared
PcG protein complex
3,744.35 100.00 345 345
PRC1 complex
930.97 14.68 91 366
histone H2AK119 ubiquitin ligase activity
720.07 4.66 20 104
ubiquitin-protein transferase activator activity
1,802.83 3.62 13 27
POZ domain binding
1,521.14 3.57 13 32
X chromosome
1,058.18 3.44 13 46
transcription regulator complex
135.13 3.39 124 3,436
heterochromatin
221.30 3.36 25 423
sex chromatin
1,797.29 3.35 12 25
pole plasm assembly
1,497.74 3.31 12 30
Totals 1811 78066

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_pir 439

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2024-04-04 Added CONSTRAINT never_in_taxon NCBITaxon:4890 (Ascomycota)
2020-11-03 Deleted RELATION part of GO:0005634 (nucleus)
2020-11-03 Deleted RELATION is a GO:0032991 (protein-containing complex)
2020-11-03 Added RELATION is a GO:0140513 (nuclear protein-containing complex)
2019-09-12 Added RELATION part of GO:0005634 (nucleus)
2019-09-12 Deleted RELATION is a GO:0044428 (obsolete nuclear part)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2013-04-18 Updated SUBSET goslim_pir
Timestamp Action Category Detail
2005-07-23 Added TERM PcG protein complex
Timestamp Action Category Detail
2008-05-13 Added DEFINITION A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
2008-05-12 Deleted DEFINITION A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
2007-08-09 Deleted SYNONYM Polycomb Group protein complex
2007-08-09 Added SYNONYM Polycomb Group protein complex
2005-07-23 Added SYNONYM Polycomb Group protein complex
2005-07-23 Added DEFINITION A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
Timestamp Action Category Detail
2020-11-03 Deleted RELATION part of GO:0005634 (nucleus)
2020-11-03 Deleted RELATION is a GO:0032991 (protein-containing complex)
2020-11-03 Added RELATION is a GO:0140513 (nuclear protein-containing complex)
2019-09-12 Added RELATION part of GO:0005634 (nucleus)
2019-09-12 Deleted RELATION is a GO:0044428 (obsolete nuclear part)
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044428 (obsolete nuclear part)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2024-04-04 Added CONSTRAINT never_in_taxon NCBITaxon:4890 (Ascomycota)
2013-04-18 Updated SUBSET goslim_pir
2008-06-09 Added SUBSET goslim_pir
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