This term is obsolete.

GO:0031720 JSON

haptoglobin binding

Molecular Function

Definition (GO:0031720 GONUTS page)

Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.

10,426 annotations

Ancestor Chart

Ancestor chart for GO:0031720
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0031720 haptoglobin binding Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0031720 based on ALL annotations
The top 63 of 63 co-occurring terms
Co-occurring Term PR S% #Together #Compared
haptoglobin binding
19,069.86 100.00 10,391 10,391
haptoglobin-hemoglobin complex
19,058.85 99.94 10,391 10,397
hemoglobin complex
16,533.57 86.70 10,391 11,985
organic acid binding
14,067.65 72.78 10,203 13,831
blood microparticle
10,722.92 55.66 10,204 18,147
oxygen carrier activity
3,599.22 18.87 10,391 55,055
oxygen transport
3,544.37 18.59 10,391 55,907
hemoglobin alpha binding
18,998.49 12.80 1,331 1,336
oxygen binding
2,125.69 11.15 10,391 93,219
hydrogen peroxide catabolic process
980.02 5.14 10,391 202,194
Totals 139720 173508444
No co-occurrence statistics for GO:0031720 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term PR S% #Together #Compared
haptoglobin binding
6,565.27 100.00 215 215
haptoglobin-hemoglobin complex
6,504.76 99.08 215 217
hemoglobin complex
5,668.81 86.35 215 249
oxygen binding
2,755.30 41.47 209 498
oxygen carrier activity
2,712.60 40.67 207 501
hemoglobin alpha binding
6,448.03 25.46 55 56
hydrogen peroxide catabolic process
847.77 12.91 215 1,665
oxygen transport
806.26 6.75 28 228
heme binding
381.04 5.79 209 3,601
nitric oxide transport
2,667.14 5.56 13 32
Totals 1936 478632

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2021-05-24 Added DEFINITION Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2018-08-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2009-07-03 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-13 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-12 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2005-10-20 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2005-10-20 Added TERM haptoglobin binding
Timestamp Action Category Detail
2005-10-20 Added TERM haptoglobin binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2021-05-24 Added DEFINITION Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2009-07-03 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-13 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-12 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2005-10-20 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
2018-08-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.