This term is obsolete.

GO:0031720 JSON

haptoglobin binding

Molecular Function

Definition (GO:0031720 GONUTS page)

Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.

10,292 annotations

Ancestor Chart

Ancestor chart for GO:0031720
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0031720 haptoglobin binding Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0031720 based on ALL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term PR S% #Together #Compared
haptoglobin binding
18,972.15 100.00 10,275 10,275
haptoglobin-hemoglobin complex
18,961.07 99.94 10,275 10,281
hemoglobin complex
16,433.89 86.62 10,275 11,862
organic acid binding
14,028.35 73.93 10,272 13,892
blood microparticle
10,713.93 55.92 10,100 17,885
oxygen carrier activity
3,626.36 19.11 10,275 53,756
oxygen transport
3,570.24 18.82 10,275 54,601
hemoglobin alpha binding
18,900.77 12.88 1,324 1,329
oxygen binding
2,142.23 11.29 10,275 90,998
hydrogen peroxide catabolic process
1,002.54 5.28 10,275 194,445
Totals 138377 142886692
No co-occurrence statistics for GO:0031720 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term PR S% #Together #Compared
haptoglobin binding
7,381.71 100.00 175 175
haptoglobin-hemoglobin complex
7,298.30 98.87 175 177
organic acid binding
7,216.75 97.77 175 179
hemoglobin complex
6,180.86 83.73 175 209
oxygen binding
2,877.06 38.98 175 449
oxygen carrier activity
2,832.89 38.38 175 456
hemoglobin alpha binding
7,239.75 28.98 51 52
hydrogen peroxide catabolic process
867.56 11.75 175 1,489
oxygen transport
965.83 7.76 28 214
nitric oxide transport
2,998.82 6.70 13 32
Totals 1805 443663

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2021-05-24 Added DEFINITION Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2018-08-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2009-07-03 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-13 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-12 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2005-10-20 Added TERM haptoglobin binding
2005-10-20 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
Timestamp Action Category Detail
2005-10-20 Added TERM haptoglobin binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2021-05-24 Added DEFINITION Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2009-07-03 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-13 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2008-05-12 Deleted DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
2005-10-20 Added DEFINITION Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
2018-08-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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