GO:0031720
JSON
haptoglobin binding
Molecular Function
Definition (GO:0031720 GONUTS page)
Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0031720 | haptoglobin binding | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0031720 based on ALL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
haptoglobin binding
|
18,972.15 | 100.00 | 10,275 | 10,275 |
haptoglobin-hemoglobin complex
|
18,961.07 | 99.94 | 10,275 | 10,281 |
hemoglobin complex
|
16,433.89 | 86.62 | 10,275 | 11,862 |
organic acid binding
|
14,028.35 | 73.93 | 10,272 | 13,892 |
blood microparticle
|
10,713.93 | 55.92 | 10,100 | 17,885 |
oxygen carrier activity
|
3,626.36 | 19.11 | 10,275 | 53,756 |
oxygen transport
|
3,570.24 | 18.82 | 10,275 | 54,601 |
hemoglobin alpha binding
|
18,900.77 | 12.88 | 1,324 | 1,329 |
oxygen binding
|
2,142.23 | 11.29 | 10,275 | 90,998 |
hydrogen peroxide catabolic process
|
1,002.54 | 5.28 | 10,275 | 194,445 |
Totals | 138377 | 142886692 |
No co-occurrence statistics for GO:0031720 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
haptoglobin binding
|
7,381.71 | 100.00 | 175 | 175 |
haptoglobin-hemoglobin complex
|
7,298.30 | 98.87 | 175 | 177 |
organic acid binding
|
7,216.75 | 97.77 | 175 | 179 |
hemoglobin complex
|
6,180.86 | 83.73 | 175 | 209 |
oxygen binding
|
2,877.06 | 38.98 | 175 | 449 |
oxygen carrier activity
|
2,832.89 | 38.38 | 175 | 456 |
hemoglobin alpha binding
|
7,239.75 | 28.98 | 51 | 52 |
hydrogen peroxide catabolic process
|
867.56 | 11.75 | 175 | 1,489 |
oxygen transport
|
965.83 | 7.76 | 28 | 214 |
nitric oxide transport
|
2,998.82 | 6.70 | 13 | 32 |
Totals | 1805 | 443663 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2021-05-24 | Added | DEFINITION | Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2018-08-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2008-05-13 | Added | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2008-04-01 | Updated | RELATION | is a GO:0005515 (protein binding) |
2005-10-20 | Added | TERM | haptoglobin binding |
2005-10-20 | Added | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-10-20 | Added | TERM | haptoglobin binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2021-05-24 | Added | DEFINITION | Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2008-05-13 | Added | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
2005-10-20 | Added | DEFINITION | Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0005515 (protein binding) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-08-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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